在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Eukaryotic translation initiation factor 5B (EIF5B), partial

  • 中文名稱:
    人EIF5B重組蛋白
  • 貨號:
    CSB-YP007581HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人EIF5B重組蛋白
  • 貨號:
    CSB-EP007581HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人EIF5B重組蛋白
  • 貨號:
    CSB-BP007581HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人EIF5B重組蛋白
  • 貨號:
    CSB-MP007581HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    EIF5B
  • Uniprot No.:
  • 別名:
    DKFZp434I036; eIF 5B; eIF-5B; Eif5b; Eukaryotic translation initiation factor 5B; FLJ10524; IF2; IF2P_HUMAN; KIAA0741; Translation initiation factor IF 2; Translation initiation factor IF-2; Translation initiation factor IF2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes.
  • 基因功能參考文獻:
    1. eIF5B promoted hepatocellular carcinoma cell proliferation and migration in vitro and in vivo partly through increasing ASAP1 expression. PMID: 27694689
    2. eIF5B silencing provides a negative feedback to deactivate MAPK signaling PMID: 27959964
    3. results indicate that the interactions between eIF1A and eIF5B are being continuously rearranged during translation initiation; presentation of a model how the dynamic eIF1A/eIF5B interaction network can promote remodeling of the translation initiation complexes, and the roles in the process played by intrinsically disordered protein segments PMID: 27325746
    4. eIF5B overexpression promotes maturation of G0-like immature oocytes and causes cell death, an alternative to G0, in serum-starved THP1 cells. PMID: 25261552
    5. The authors show that the cleavage of initiation factor eIF5B during enteroviral infection, along with the viral internal ribosome entry site, plays a role in mediating viral translation under conditions that are nonpermissive for host cell translation. PMID: 21697471
    6. determination of binding site on eukaryotic initiation factor 1A PMID: 12569173
    7. Transfected nuclear factor 2 trans activates the IF2 promoter in a cell line. PMID: 17161026
    8. binding of eIF5B might induce conformational changes in both subunits, with ribosomal segments wrapping around the factor PMID: 17568775
    9. 3Cpro-mediated cleavage of eIF5B may thus play an accessory role in the shutoff of translation that occurs in enterovirus-infected cells. PMID: 18572216

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, IF-2 subfamily
  • 數據庫鏈接:

    HGNC: 30793

    OMIM: 606086

    KEGG: hsa:9669

    STRING: 9606.ENSP00000289371

    UniGene: Hs.158688



主站蜘蛛池模板: 日本少妇xxx做受| 粉嫩av久久一区二区三区| 亚瑟国产精品久久| 麻豆人妻少妇精品无码专区| 亚洲精品午夜无码专区| av狼友无码国产在线观看| 成人麻豆亚洲综合无码精品| 777午夜精品免费观看| 亚洲欧美国产精品久久| 色播亚洲视频在线观看| 国产开嫩苞实拍在线播放视频| 亚洲精品少妇高清30p| 大又大又粗又硬又爽少妇毛片| 国产超碰人人爽人人做人人添| 欧美xxxxx高潮喷水麻豆| 亚洲日韩色在线影院性色| 麻花传媒mv国产免费观看视频| 久久综合亚洲色一区二区三区| 国产又色又爽又刺激视频| 女被啪到深处喷水gif动态图| 131mm少妇做爰视频| 一本一本久久a久久精品综合| 国产亚洲精品久久久性色情软件| 久久人人爽人人爽爽久久小说| 国产内射爽爽大片| 少妇私密会所按摩到高潮呻吟| 黄在线看片免费人成视频| 精品国产亚洲午夜精品av| 国内精品久久久久久不卡影院| 人妻少妇被粗大爽9797pw| 国产aⅴ视频免费观看| 一边摸一边叫床一边爽av| 亚洲日韩一区二区三区| 国产精品爽爽久久久久久竹菊| 精品国产一区二区三区国产区| 国产又a又黄又潮娇喘视频| 色偷偷888欧美精品久久久| 综合在线 亚洲 成人 欧美| 亚洲精品综合一区二区| 成人国产亚洲精品a区天堂| 免费男人下部进女人下部视频 |