在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Estradiol 17-beta-dehydrogenase 11 (HSD17B11)

In Stock
  • 中文名稱:
    人HSD17B11重組蛋白
  • 貨號:
    CSB-EP843318HU
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    HSD17B11
  • Uniprot No.:
  • 別名:
    17 beta HSD 11; 17 beta HSD XI; 17 BETA HSD11; 17 BETA HSDXI ; 17 beta hydroxysteroid dehydrogenase 11; 17 beta hydroxysteroid dehydrogenase type XI; 17 beta hydroxysteroid dehydrogenase XI; 17-beta-HSD 11; 17-beta-HSD XI; 17-beta-hydroxysteroid dehydrogenase 11; 17-beta-hydroxysteroid dehydrogenase XI; 17betaHSD11; 17betaHSDXI; 17bHSD11; CTCL associated antigen HD CL 03; CTCL tumor antigen HD CL 03 ; CTCL-associated antigen HD-CL-03; Cutaneous T cell lymphoma associated antigen HD CL 03; Cutaneous T-cell lymphoma-associated antigen HD-CL-03; Dehydrogenase/reductase SDR family member 8; DHB11_HUMAN; DHRS8; Estradiol 17 beta dehydrogenase 11; Estradiol 17-beta-dehydrogenase 11; Hsd17b11; Hydroxysteroid (17 beta) dehydrogenase 11; PAN1B; Retinal short chain dehydrogenase/reductase 2; Retinal short-chain dehydrogenase/reductase 2; RETSDR2; SDR16C2; SDR2; Short chain dehydrogenase/reductase family 16C member 2; T cell lymphoma associated antigen HD CL 03
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    46.8kDa
  • 表達區(qū)域:
    20-300aa
  • 氨基酸序列
    ESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKQKISVKFDAVIGYKMKAQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
  • 基因功能參考文獻:
    1. knowledge of its in vitro activity together with a newly described expression pattern at the protein level in tissues involved in steroidogenesis and detoxification could suggest a potential role of DHRS8 in vivo PMID: 26472732
    2. hydroxysteroid (17-beta) dehydrogenase 11 transcription in prostate cancer cells is regulated by Sp1 transcription factor and C-EBP alpha PMID: 21549806
    3. Role for 17-beta-HSDXI in androgen metabolism during steroidogenesis. PMID: 12697717
    4. Mutation analyses suggest that the PAT-like motif in 17betaHSD11 will not be functionally similar to the canonical PAT motif. PMID: 18804447
    5. Increased Pan1b is associated with prostate cancer of seminal vesicle invasion. PMID: 19469652

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum. Lipid droplet.
  • 蛋白家族:
    Short-chain dehydrogenases/reductases (SDR) family, 17-beta-HSD 3 subfamily
  • 組織特異性:
    Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in
  • 數(shù)據(jù)庫鏈接:

    HGNC: 22960

    OMIM: 612831

    KEGG: hsa:51170

    STRING: 9606.ENSP00000351035

    UniGene: Hs.594923



主站蜘蛛池模板: 国产精品玖玖玖在线| 最新69国产成人精品视频免费| 日产精品一区2区卡四卡二卡| 亚洲 综合 校园 欧美 制服| 国产在线无码播放不卡视频| 好紧好爽好深再快点av在线| 亚洲成av人片天堂网| 激情欧美成人久久综合| 99久久精品无码一区二区三区| 国产麻豆放荡av剧情演绎| 真人做作爱视频| 国产成人8x人网站视频| 人狥杂交一区欧美二区| 日韩精品无码熟人妻视频| 国产成人久久精品二区三区| 国产激情久久久久影院老熟女| 国产成人麻豆精品午夜福利在线 | 白丝乳交内射一二三区| 玩弄丰满熟妇xxxxx性60 | 日韩经典精品无码一区| 成人亚洲欧美成αⅴ人在线观看| 国内露脸少妇精品视频| 久久久久久人妻一区二区三区| 亚洲vs日韩vs欧美vs久久| 9久9久女女热精品视频在线观看| 亚洲欧美在线观看品| 欧美牲交a欧美牲交aⅴ| 51国偷自产一区二区三区| 国产午夜福利在线观看红一片| 无码欧美黑人xxx一区二区三区 | 成人欧美一区二区三区视频| 国产又爽又粗又猛的视频| 一个人看的日本hd免费| 亚洲精品国产精品乱码不99| 欧美一道本一区二区三区| 中国少妇videos呻吟| 好吊妞人成视频在线观看27du| 男女啪啪永久免费观看网站| 色欲av无码一区二区三区| 又黄又粗又爽免费观看| 中文字字幕在线精品乱码|