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Recombinant Human ETS translocation variant 2 (ETV2)

  • 中文名稱:
    人ETV2重組蛋白
  • 貨號:
    CSB-YP007855HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人ETV2重組蛋白
  • 貨號:
    CSB-EP007855HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人ETV2重組蛋白
  • 貨號:
    CSB-EP007855HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人ETV2重組蛋白
  • 貨號:
    CSB-BP007855HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人ETV2重組蛋白
  • 貨號:
    CSB-MP007855HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ETV2
  • Uniprot No.:
  • 別名:
    ETV2; ER71; ETSRP71ETS translocation variant 2; Ets-related protein 71
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-342
  • 氨基酸序列
    MDLWNWDEAS PQEVPPGNKL AGLEGAKLGF CFPDLALQGD TPTATAETCW KGTSSSLASF PQLDWGSALL HPEVPWGAEP DSQALPWSGD WTDMACTAWD SWSGASQTLG PAPLGPGPIP AAGSEGAAGQ NCVPVAGEAT SWSRAQAAGS NTSWDCSVGP DGDTYWGSGL GGEPRTDCTI SWGGPAGPDC TTSWNPGLHA GGTTSLKRYQ SSALTVCSEP SPQSDRASLA RCPKTNHRGP IQLWQFLLEL LHDGARSSCI RWTGNSREFQ LCDPKEVARL WGERKRKPGM NYEKLSRGLR YYYRRDIVRK SGGRKYTYRF GGRVPSLAYP DCAGGGRGAE TQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
  • 基因功能參考文獻:
    1. REVIEW. the interplay among the ETS transcription factor ETV2, vascular endothelial growth factor, and its receptor VEGFR2/FLK1 is essential for hematopoietic and vascular development. Emerging studies also support the role of these three factors and possible interplay in hematopoietic and vascular regeneration. PMID: 28026128
    2. Single-factor ETV2 transduction successfully reprogrammed dermal fibroblasts into functional EPCs. PMID: 27488544
    3. ETV2 alone can directly reprogram postnatal cells to functional, mature endothelial cells. PMID: 28003219
    4. ets variant 2 (ETV2) alone directly converts primary human adult skin fibroblasts into functional vascular endothelial cells. PMID: 25540418
    5. identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp PMID: 18270322

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  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    ETS family
  • 數據庫鏈接:

    HGNC: 3491

    OMIM: 609358

    KEGG: hsa:2116

    STRING: 9606.ENSP00000384524

    UniGene: Hs.194061



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