在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human EH domain-containing protein 2 (EHD2)

Recombinant Human EH domain-containing protein 2 (EHD2)

  • 中文名稱：
    人EHD2重組蛋白
  • 貨號：
    CSB-YP873710HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EHD2重組蛋白
  • 貨號：
    CSB-EP873710HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EHD2重組蛋白
  • 貨號：
    CSB-EP873710HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EHD2重組蛋白
  • 貨號：
    CSB-BP873710HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EHD2重組蛋白
  • 貨號：
    CSB-MP873710HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    EH domain containing 2; EH domain containing 3; EH domain containing protein 2; EH domain-containing protein 2; EHD 2; Ehd2; EHD2_HUMAN; EHD3; FLJ96617; PAST 2; PAST homolog 2; PAST2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-543
  • 氨基酸序列
    MFSWLKRGGA RGQQPEAIRT VTSALKELYR TKLLPLEEHY RFGAFHSPAL EDADFDGKPM VLVAGQYSTG KTSFIQYLLE QEVPGSRVGP EPTTDCFVAV MHGDTEGTVP GNALVVDPDK PFRKLNPFGN TFLNRFMCAQ LPNQVLESIS IIDTPGILSG AKQRVSRGYD FPAVLRWFAE RVDLIILLFD AHKLEISDEF SEAIGALRGH EDKIRVVLNK ADMVETQQLM RVYGALMWAL GKVVGTPEVL RVYIGSFWSQ PLLVPDNRRL FELEEQDLFR DIQGLPRHAA LRKLNDLVKR ARLVRVHAYI ISYLKKEMPS VFGKENKKKQ LILKLPVIFA KIQLEHHISP GDFPDCQKMQ ELLMAHDFTK FHSLKPKLLE ALDEMLTHDI AKLMPLLRQE ELESTEVGVQ GGAFEGTHMG PFVERGPDEA MEDGEEGSDD EAEWVVTKDK SKYDEIFYNL APADGKLSGS KAKTWMVGTK LPNSVLGRIW KLSDVDRDGM LDDEEFALAS HLIEAKLEGH GLPANLPRRL VPPSKRRHKG SAE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane.
  • 基因功能參考文獻：
    1. Our prognostic model is useful for predicting persistent/recurrent disease after surgery of Papillary thyroid carcinoma (PTC). EHD2 mRNA expression could be a novel prognostic marker for PTC patients. PMID: 28358874
    2. EHD2 expression, along with the epithelial marker E-cadherin, was markedly reduced in tumor tissues than in adjacent noncancerous tissues. Molecular data indicated that EHD2 inhibited migration and invasion of hepatocellular carcinoma probably by interacting with E-cadherin. PMID: 27221498
    3. Data suggest that the EH-domain containing 2 protein (EHD2) NPF phenylalanine residue is crucial for EHD2 localization to the plasma membrane, whereas the proline residue is essential for EHD2 dimerization and binding. PMID: 25875965
    4. EHD2 can inhibit the metastasis of human breast cancer by regulating the epithelial-to-mesenchymal transition markers E-cadherin and N-cadherin. PMID: 25758127
    5. Downregulation of EHD2 was associated with migration and invasion by abrogating the expression of Rac1 in breast cancer patients. PMID: 25557791
    6. Phosphatidylinositol 4,5-bisphosphate controls EHD2 plasma membrane localization. PMID: 24040268
    7. Our results suggested that EHD2 low expression is involved in the pathogenesis of human esophageal squamous cell carcinoma PMID: 23354948
    8. EHD2 participates in the sarcolemma repair. PMID: 22679923
    9. Assembly of EHD2 stabilized and constrained caveolae to the plasma membrane to control turnover, and depletion of EHD2, resulting in endocytic and more dynamic and short-lived caveolae. PMID: 22323287
    10. Among three EHD proteins (EHD1-EHD3) that were tested, only EHD2 accumulates in the nucleus under nuclear export inhibition treatment. PMID: 22448906
    11. Confining caveolae to the plasma membrane by EHD2 relied on its capacity to link caveolae to actin filaments. PMID: 22505029
    12. EHD2 regulates trafficking from the plasma membrane by controlling Rac1 activity. PMID: 21756249

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, caveola; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family, EHD subfamily
  • 組織特異性：
    Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 3243

    OMIM: 605890

    KEGG: hsa:30846

    STRING: 9606.ENSP00000263277

    UniGene: Hs.744963



主站蜘蛛池模板： 久久久久国产精品人妻aⅴ天堂 | 777午夜福利理伦电影网| 国产精品天天狠天天看| 男女猛烈xx00免费视频试看| 国产亚洲精品久久久久久久软件| 亚洲精品无码高潮喷水a片软| 国产精品一区二区av交换| 极品粉嫩嫩模大尺度无码视频| 国模欢欢炮交啪啪150| 久久99青青精品免费观看| 国产真实露脸乱子伦| 精品国产青草久久久久福利| 国产精品无码mv在线观看| 国产人妻精品区一区二区三区| 色婷婷亚洲一区二区综合| 国产女人18毛片水真多1| 亚洲中文无码a∨在线观看| 18成禁人视频免费| 久久人妻精品白浆国产| 色偷偷88888欧美精品久久久 | 中文天堂在线资源www| 中文字幕欧美亚州视频免费| 国产偷亚洲偷欧美偷精品| 国产精品成人永久在线四虎| 日韩欧美亚洲综合久久影院ds| 最近日本免费观看高清视频| 成 人 色 网 站免费观看| 国产精品嫩草影院久久| 国产乱码一区二区三区爽爽爽| 国产精品va无码一区二区| 一本久久综合亚洲鲁鲁五月天| 天码欧美日本一道免费| 东北老女人高潮大叫对白| 欧美深性狂猛ⅹxxx深喉| 动漫av纯肉无码av电影网| 少妇的丰满人妻hd高清| 国产精品ⅴ无码大片在线看| 天堂网www天堂在线资源| 嫩草研究院久久久精品| 国产精品熟女高潮视频| 日本高清一二三不卡区|