在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human E3 ubiquitin-protein ligase MARCH2 (41335), partial

  • 中文名稱:
    Recombinant Human E3 ubiquitin-protein ligase MARCH2(41335),partial
  • 貨號:
    CSB-YP878948HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human E3 ubiquitin-protein ligase MARCH2(41335),partial
  • 貨號:
    CSB-EP878948HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human E3 ubiquitin-protein ligase MARCH2(41335),partial
  • 貨號:
    CSB-EP878948HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human E3 ubiquitin-protein ligase MARCH2(41335),partial
  • 貨號:
    CSB-BP878948HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MARCH2
  • Uniprot No.:
  • 別名:
    MARCHF2; MARCH2; RNF172; HSPC240; E3 ubiquitin-protein ligase MARCHF2; Membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; MARCH-II; RING finger protein 172; RING-type E3 ubiquitin transferase MARCHF2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.
  • 基因功能參考文獻:
    1. In this study, the authors found the expression of MARCH2 to be upregulated upon HIV-1 infection. MARCH2 inhibits the production and infection of HIV-1 through ligase activity-dependent envelope protein degradation and/or intracellular retention. PMID: 29573664
    2. MARCH2 has a role in regulating autophagy by promoting CFTR ubiquitination and degradation and PIK3CA-AKT-MTOR signaling PMID: 27308891
    3. The MARCH2 E3 ligase activity regulates cell surface beta(2)AR expression and, consequently, its signaling. PMID: 23166351
    4. Depletion of MARCH-II by small interfering RNA perturbed the trans-Golgi network (TGN) localization of syntaxin 6 and TGN38/46 PMID: 15689499
    5. MARCH2 is co-localized with DLG1 at sites of cell-cell contact. PMID: 17980554

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
  • 組織特異性:
    Broadly expressed.
  • 數據庫鏈接:

    HGNC: 28038

    OMIM: 613332

    KEGG: hsa:51257

    STRING: 9606.ENSP00000215555

    UniGene: Hs.631861



主站蜘蛛池模板: 丰满少妇高潮惨叫久久久| 亚洲熟少妇在线播放999| 成人女人黄网站免费视频| 2021国产精品午夜久久| 综合网日日天干夜夜久久| 中文字幕日本最新乱码视频| 亚洲精品无码高潮喷水a片软| 顶级欧美做受xxx000| 一区二区三区在线 | 欧洲| 久久亚洲私人国产精品va| 国产制服丝袜亚洲高清| 精品免费看国产一区二区| 国产成人久久精品二区三区| 欧美人与禽zoz0性伦交| 亚洲综合最新无码2020av| 欧洲美熟女乱又伦av| 国产精品偷窥熟女精品视频| 国模裸体无码xxxx视频| 免费无码又爽又刺激高潮的动态图| av天堂午夜精品蜜臀av| 澳门永久av免费网站| 欧美变态暴力牲交videos| 最新69成人精品视频免费| 国产男女猛烈无遮挡免费视频网站| 无码精品人妻一区二区三区免费看 | 国产精品sp调教打屁股| 亚洲婷婷六月的婷婷| 欧美国产亚洲日韩在线二区| 久久久久高潮综合影院| 人妻另类 专区 欧美 制服| 色欲色香天天天综合网站| 麻花传媒mv国产免费观看视频| 国产sm调教折磨视频| 东京热一精品无码av| 久久精品九九亚洲精品天堂| 国产又粗又大又黄| 免费国产黄网站在线观看视频| 2018年秋霞无码片| 九九精品无码专区免费| 欧美日韩一区二区成人午夜电影| 上司人妻互换hd无码|