在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Dermokine (DMKN)

  • 中文名稱:
    人DMKN重組蛋白
  • 貨號:
    CSB-YP006965HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人DMKN重組蛋白
  • 貨號:
    CSB-EP006965HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人DMKN重組蛋白
  • 貨號:
    CSB-EP006965HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人DMKN重組蛋白
  • 貨號:
    CSB-BP006965HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人DMKN重組蛋白
  • 貨號:
    CSB-MP006965HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DMKN
  • Uniprot No.:
  • 別名:
    Dermokine; DMKN; DMKN_HUMAN; Epidermis-specific secreted protein SK30/SK89; FLJ79374; UNQ729; UNQ729/PRO1411; ZD52F10
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    22-476
  • 氨基酸序列
    GPLQSGEES TGTNIGEALG HGLGDALSEG VGKAIGKEAG GAAGSKVSEA LGQGTREAVG TGVRQVPGFG VADALGNRVG EAAHALGNTG HEIGRQAEDV IRHGADAVRG SWQGVPGHNG AWETSGGHGI FGSQGGLGGQ GQGNPGGLGT PWVHGYPGNS AGSFGMNPQG APWGQGGNGG PPNFGTNTQG AVAQPGYGSV RASNQNEGCT NPPPSGSGGG SSNSGGGSGS QSGSSGSGSN GDNNNGSSSG GSSSGSSSGG SSGGSSGGSS GNSGGSRGDS GSESSWGSST GSSSGNHGGS GGGNGHKPGC EKPGNEARGS GESGIQNSET SPGMFNFDTF WKNFKSKLGF INWDAINKNQ VPPPSTRALL YFSRLWEDFK QNTPFLNWKA IIEGADASSL QKRAGRDDQN YNYNQHAYPT AYGGKYSVKT PAKGGVSPSS SASRVQPGLL QWVKFW
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May act as a soluble regulator of keratinocyte differentiation.
  • 基因功能參考文獻:
    1. we showed that DMKN loss of function in Patu-8988 and PANC-1 pancreatic cancer cell lines resulted in reduced phosphorylation of STAT3.these data suggested that DMKN could be a potential prognostic biomarker and therapeutic target in pancreatic cancer. PMID: 28795470
    2. These results suggest that dermokine-beta delays early cutaneous wound healing in part by inhibiting expression of CXC chemokines containing the ERL-sequence motif. PMID: 23428944
    3. Serum DK is a potential biomarker in intraductal papillary mucinous neoplasm and invasive ductal carcinoma, when used in combination with conventional biomarkers. PMID: 23060565
    4. Dermokine-beta impairs ERK signaling through direct binding to GRP78 PMID: 22735594
    5. Dmkndelta activates Rab5 function and thus is involved in the early endosomal trafficking. PMID: 21423773
    6. Analysis of alternative spliced transcripts produced from the dermokine gene. PMID: 16374476
    7. Dermokine gene is expressed in epithelial tissues other than the skin and this expression is transcriptionally and posttranscriptionally complex. PMID: 17380110

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Dermokine family
  • 組織特異性:
    Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expr
  • 數據庫鏈接:

    HGNC: 25063

    KEGG: hsa:93099

    STRING: 9606.ENSP00000342012

    UniGene: Hs.417795



主站蜘蛛池模板: 欧美三级不卡在线播放| 亚洲免费视频免在线观看| 亚洲老熟女性亚洲| 久久午夜夜伦鲁鲁片免费无码| 国产女人的高潮国语对白| 国产亚洲精品久久久ai换| 在线成人a毛片免费播放| 一本大道无码av天堂| 又粗又黄又猛又爽大片免费| 成人午夜福利视频| 看曰本女人大战黑人视频| 精品自拍亚洲一区在线| 久久久久久久波多野结衣高潮| 男女啪啪高清无遮挡免费| 亚洲人成无码网站| 欧美人与禽zoz0性伦交| 国产美女精品自在线拍免费| 黑人与中国少妇xxxx视频| 国产东北肥熟老胖女| 精品乱码一区二区三区四区| 失禁潮痉挛潮喷av在线无码 | 中文无码一区二区不卡av| 亚洲乱码无人区卡1卡2卡3| 久久亚洲精品无码av红樱桃| 全国最大成人网| 99视频偷窥在线精品国自产拍 | 97av麻豆蜜桃一区二区| 中文字幕在线播放| 3d动漫精品一区二区三区| 无码人妻精品中文字幕不卡| 亚洲伦无码中文字幕另类 | 噜噜久久噜噜久久鬼88| 成人精品一区二区三区电影| 国产精品乱码在线观看| 日本久久高清一区二区三区毛片| 日韩免费无砖专区2020狼| 中文字幕人成无码人妻综合社区| 亚洲第一成人网站在线播放| 国产成人精品一区二区三区免费看| 日韩久久久久久中文人妻| ass日本丰满熟妇pics|