在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Delta and Notch-like epidermal growth factor-related receptor (DNER), partial

In Stock
  • 中文名稱:
    Recombinant Human Delta and Notch-like epidermal growth factor-related receptor (DNER), partial
  • 貨號:
    CSB-MP818784HUd7
  • 說明書:
  • 規(guī)格:
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • The purity of DNER was greater than 90% as determined by SEC-HPLC
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
    Greater than 90% as determined by SEC-HPLC.
  • 生物活性:
    Not Test
  • 基因名:
    DNER
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    66.0 kDa
  • 表達(dá)區(qū)域:
    35-640aa
  • 氨基酸序列
    NPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGRLVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    C-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
  • 基因功能參考文獻(xiàn):
    1. quantum dot-based immunofluorescent imaging and quantitative analytical system (QD-IIQAS) is an easy and accurate method for assessing DNER and the DNER expression was an independent prognostic factor in prostate cancer. PMID: 29843212
    2. Collectively, our study identified an unexpected transcriptional repression function of the BET bromodomain and a novel mechanism for TAZ upregulation. PMID: 27717711
    3. our findings show that targeting BET proteins for degradation represents an effective therapeutic strategy for Triple-negative breast cancers (TNBC)treatment PMID: 28209615
    4. is not a Notch ligand PMID: 27622512
    5. we review and discuss the structural biology of BET family BDs and their applications in major diseases. PMID: 27240990
    6. DNER rs1861612 C to T change and variant T genotype may contribute to T2DM in a Chinese Han population PMID: 25300688
    7. These studies implicate DNER as a susceptibility gene for T2DM in American Indians. PMID: 24101674
    8. Our data suggest that clathrin-independent endocytosis is critical for the polarized targeting of somatodendritic proteins(DNER). PMID: 20367751
    9. The inhibition of DNER protein resulted in an increase in adipocyte maturation, partly via a reduction of cell proliferation through elevation of CCAAT-Enhancer-Binding Protein-delta expression. PMID: 20070733
    10. expression in developing and mature central nervous system PMID: 11950833

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Expressed in brain, spinal cord and adrenal gland.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24456

    OMIM: 607299

    KEGG: hsa:92737

    STRING: 9606.ENSP00000345229

    UniGene: Hs.234074



主站蜘蛛池模板: 日日鲁鲁鲁夜夜爽爽狠狠| 精品人妻av区波多野结衣| 艳妇臀荡乳欲伦交换h在线观看| 性人久久网av| 少妇无码一区二区二三区| 国产午夜亚洲精品久久| 日韩 高清 无码 人妻| 免费无码av一区二区三区| 欧美国产激情18| 东京热一精品无码av| 无码精品人妻一区二区三区av| 最新日韩精品中文字幕| 亚洲熟妇av日韩熟妇在线 | 午夜免费无码福利视频麻豆| 99精品国产福利一区二区| 少妇伦子伦精品无吗| 国产乱国产乱老熟300部视频| 亚洲综合另类小说色区| 天天躁夜夜躁狠狠综合2020| 秋霞影院午夜伦a片欧美| 久久久www成人免费毛片| 美女视频黄的全免费视频网站| 亚洲色国产欧美日韩| 日韩一区二区三区高清电影| 四虎成人精品国产永久免费无码 | 中文字幕无码精品三级在线电影| 久久久精品中文字幕乱码18| 亚洲综合av在线在线播放| 日本新janpanese乱熟| 精品久久久久久国产潘金莲| 青青视频免费观看免费| 18禁美女裸体无遮挡网站| 国产麻豆天美果冻无码视频| 午夜亚洲国产理论片二级港台二级| 久久精品99国产精品日本| 十八18禁国产精品www| 日本狂喷奶水在线播放212 | 亚洲成aⅴ人最新无码| 群交射精白浆视频| 99精品无码一区二区| 成人性欧美丨区二区三区|