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  4. Recombinant Human Cytosolic phospholipase A2 delta (PLA2G4D), partial

Recombinant Human Cytosolic phospholipase A2 delta (PLA2G4D), partial

  • 中文名稱：
    人PLA2G4D重組蛋白
  • 貨號：
    CSB-YP771467HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PLA2G4D重組蛋白
  • 貨號：
    CSB-EP771467HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PLA2G4D重組蛋白
  • 貨號：
    CSB-EP771467HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PLA2G4D重組蛋白
  • 貨號：
    CSB-BP771467HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PLA2G4D重組蛋白
  • 貨號：
    CSB-MP771467HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    cPLA2 delta; cPLA2-delta; cPLA2delta; Cytosolic phospholipase A2 delta; PA24D_HUMAN; Phospholipase A2 group IVD; phospholipase A2; group IVD (cytosolic); Pla2g4d
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has a preference for linoleic acid at the sn-2 position.
  • 基因功能參考文獻：
    1. These findings suggested that the polymorphism of PLA2G4D rs4924618 may have a protective influence on the SPTB susceptibility in a Chinese population, supporting a role for genetics in the association between PG synthesis and preterm birth. PMID: 28440406
    2. The findings suggest that PLA2 inhibition or CD1a blockade may have therapeutic potential for psoriasis. PMID: 27670592
    3. study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP, CBFA2T3, AMOTL1, FAT4, FBXO11, PLA2G4D, TRRAP and USH2A. PMID: 24349473
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    5. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
    6. cPLA(2)delta exhibits a unique distribution pattern compared with that of known cPLA(2) subtypes and may play a critical role in inflammation in psoriatic lesions PMID: 14709560
    7. Observational study of gene-disease association. (HuGE Navigator) PMID: 18686860
    8. Observational study of gene-disease association. (HuGE Navigator) PMID: 16213696

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  • 亞細胞定位：
    Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.
  • 組織特異性：
    Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues. Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoid
  • 數據庫鏈接：

    HGNC: 30038

    OMIM: 612864

    KEGG: hsa:283748

    STRING: 9606.ENSP00000290472

    UniGene: Hs.380225



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