Recombinant Human Cytosolic carboxypeptidase 2 (AGBL2), partial

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 2(AGBL2) ,partial
貨號：

CSB-YP732978HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 2(AGBL2) ,partial
貨號：

CSB-EP732978HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 2(AGBL2) ,partial
貨號：

CSB-EP732978HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 2(AGBL2) ,partial
貨號：

CSB-BP732978HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 2(AGBL2) ,partial
貨號：

CSB-MP732978HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

AGBL2
Uniprot No.：

Q5U5Z8
別名：

AGBL 2; AGBL2; ATP/GTP binding protein like 2 ; ATP/GTP-binding protein-like 2; Carboxypeptidase 2 cytosolic; CBPC2_HUMAN; CCP2; Cytosolic carboxypeptidase 2; FLJ23598
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.
基因功能參考文獻(xiàn)：
1. Findings suggest that ATP/GTP binding protein like 2 (AGBL2) plays a critical oncogenic role in the pathogenesis of hepatocellular carcinoma (HCC) through modulation on immunity-related GTPase family, M protein (IRGM)-regulated autophagy and aurora kinase A (Aurora A) activity. PMID: 29126912
2. Suggest role for AGBL2 in cell proliferation and chemotherapy resistance in gastric cancer. PMID: 25916089
3. High AGBL2 expression is associated with breast cancer. PMID: 24884516
4. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY-bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis. PMID: 21303978
亞細(xì)胞定位：

Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
蛋白家族：

Peptidase M14 family
數(shù)據(jù)庫鏈接：

HGNC: 26296

OMIM: 617345

KEGG: hsa:79841

STRING: 9606.ENSP00000298861

UniGene: Hs.147377