在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1)

Recombinant Human Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1)

  • 中文名稱：
    人DYNC1LI1重組蛋白
  • 貨號：
    CSB-YP897312HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人DYNC1LI1重組蛋白
  • 貨號：
    CSB-EP897312HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人DYNC1LI1重組蛋白
  • 貨號：
    CSB-EP897312HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DYNC1LI1重組蛋白
  • 貨號：
    CSB-BP897312HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DYNC1LI1重組蛋白
  • 貨號：
    CSB-MP897312HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DYNC1LI1
  • Uniprot No.：
  • 別名：
    Cytoplasmic dynein 1 light intermediate chain 1; cytosolic; DC1L1_HUMAN; DLC-A; DNCLI1; dync1li1; Dynein cytoplasmic 1 light intermediate chain 1; Dynein cytoplasmic light intermediate polypeptide 1; Dynein light chain A; Dynein light intermediate chain 1; Dynein light intermediate chain 1 cytosolic; FLJ10219; LIC1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-523
  • 氨基酸序列
    MAAVGRVGSF GSSPPGLSST YTGGPLGNEI ASGNGGAAAG DDEDGQNLWS CILSEVSTRS RSKLPAGKNV LLLGEDGAGK TSLIRKIQGI EEYKKGRGLE YLYLNVHDED RDDQTRCNVW ILDGDLYHKG LLKFSLDAVS LKDTLVMLVV DMSKPWTALD SLQKWASVVR EHVDKLKIPP EEMKQMEQKL IRDFQEYVEP GEDFPASPQR RNTASQEDKD DSVVLPLGAD TLTHNLGIPV LVVCTKCDAI SVLEKEHDYR DEHFDFIQSH IRKFCLQYGA ALIYTSVKEN KNIDLVYKYI VQKLYGFPYK IPAVVVEKDA VFIPAGWDND KKIGILHENF QTLKAEDNFE DIITKPPVRK FVHEKEIMAE DDQVFLMKLQ SLLAKQPPTA AGRPVDASPR VPGGSPRTPN RSVSSNVASV SPIPAGSKKI DPNMKAGATS EGVLANFFNS LLSKKTGSPG GPGVSGGSPA GGAGGGSSGL PPSTKKSGQK PVLDVHAELD RITRKPVTVS PTTPTSPTEG EAS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
  • 基因功能參考文獻：
    1. conserved mechanism of effector interaction with dynein-dynactin necessary for processive motility PMID: 29515126
    2. the DYNC1I1 deficiency, a neuron-specific dynein intermediate chain, causes neuronal atrophy in primary hippocampal neurons. PMID: 27510948
    3. This work reveals the structural details of Hook3's interaction with dynein and offers insight into how cargo adaptors form processive dynein-dynactin motor complexes. PMID: 27482052
    4. although dynein lacking light intermediate chains (LICs) drives microtubule gliding at normal rates, the LICs are required for the formation and maintenance of a bipolar spindle. PMID: 25422374
    5. using a variety of complementary approaches, our results indicate a novel specific role for the LICs in dynein recruitment to components of the late endocytic pathway. PMID: 21169557
    6. Rab11a, FIP3 and DLIC-1 form a ternary complex and DLIC-1 colocalises with endogenous FIP3 and Rab11a in A431 cells. PMID: 20026645
    7. Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint PMID: 19229290

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    Dynein light intermediate chain family
  • 數據庫鏈接：

    HGNC: 18745

    OMIM: 615890

    KEGG: hsa:51143

    STRING: 9606.ENSP00000273130

    UniGene: Hs.529495



主站蜘蛛池模板： 性开放的欧美大片| 国产精品久久自在自线不卡| 777米奇影院狠狠色| 好爽又高潮了毛片免费下载| 久久在线视频免费观看| 2021国产精品一卡2卡三卡4卡| 久久免费午夜福利院| 亚洲精品久久国产精品浴池| 久久中文字幕人妻熟女| 久久久久亚洲精品无码网址| 成年男人裸j照无遮挡无码| 日本高清在线www3344| 两性色午夜视频免费无码| 久久天天躁夜夜躁狠狠85麻豆 | 国产成人久久a免费观看| 国产午睡沙发被弄醒完整版| 就去干成人网| 一本一道波多野结衣av黑人| av无码国产精品麻豆| 欧美人与动牲交免费观看网| 国产一区日韩二区欧美三区| 男人下部进女人下部视频| 欧美激情猛片xxxⅹ大3| 亚洲精品久久久久午夜福利 | 日韩精品无码人妻一区二区三区| 精品国产自在现线电影| 久久久久无码国产精品一区| 久久亚洲精品无码网站| 亚洲а∨天堂久久精品| 日本精品人妻无码免费大全| 亚洲最大av无码国产| 两性色午夜视频免费老司机| 国产精品久久久久久不卡盗摄| 亚洲啪av永久无码精品放毛片| 18禁勿入网站入口永久| 精品少妇无码一区二区三批| 一日本道a高清免费播放| 大陆精大陆国产国语精品 | 精品国产自在现线看久久| 成人欧美一区二区三区黑人| 无码h黄动漫在线播放网站 |