在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1)

  • 中文名稱:
    人DYNC1I1重組蛋白
  • 貨號:
    CSB-YP007293HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人DYNC1I1重組蛋白
  • 貨號:
    CSB-EP007293HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人DYNC1I1重組蛋白
  • 貨號:
    CSB-EP007293HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人DYNC1I1重組蛋白
  • 貨號:
    CSB-MP007293HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DYNC1I1
  • Uniprot No.:
  • 別名:
    Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; cytosolic; DC1I1_HUMAN; DH IC 1; DH IC-1; DH IC1; DNCI1; DNCIC1; Dync1i1; Dynein cytoplasmic 1 intermediate chain 1; Dynein intermediate chain 1; Dynein intermediate chain 1; cytosolic; Dynein; cytoplasmic; intermediate polypeptide 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-645
  • 氨基酸序列
    MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEADMQ QKKEPVQDDS DLDRKRRETE ALLQSIGISP EPPLVQPLHF LTWDTCYFHY LVPTPMSPSS KSVSTPSEAG SQDSGDLGPL TRTLQWDTDP SVLQLQSDSE LGRRLHKLGV SKVTQVDFLP REVVSYSKET QTPLATHQSE EDEEDEEMVE SKVGQDSELE NQDKKQEVKE APPRELTEEE KQQILHSEEF LIFFDRTIRV IERALAEDSD IFFDYSGREL EEKDGDVQAG ANLSFNRQFY DEHWSKHRVV TCMDWSLQYP ELMVASYNNN EDAPHEPDGV ALVWNMKFKK TTPEYVFHCQ SSVMSVCFAR FHPNLVVGGT YSGQIVLWDN RSHRRTPVQR TPLSAAAHTH PVYCVNVVGT QNAHNLITVS TDGKMCSWSL DMLSTPQESM ELVYNKSKPV AVTGMAFPTG DVNNFVVGSE EGTVYTACRH GSKAGIGEVF EGHQGPVTGI NCHMAVGPID FSHLFVTSSF DWTVKLWTTK HNKPLYSFED NADYVYDVMW SPVHPALFAC VDGMGRLDLW NLNNDTEVPT ASVAIEGASA LNRVRWAQAG KEVAVGDSEG RIWVYDVGEL AVPHNDEWTR FARTLVEIRA NRADSEEEGT VELSA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
  • 基因功能參考文獻:
    1. SQSTM1 is required for proper dynein motility and trafficking along microtubules. PMID: 25015291
    2. Deletions of the exons with regulatory potential of DYNC1I1 are an example of the emerging role of exonic enhancer elements and their implications in congenital malformation syndromes PMID: 25231166
    3. NCAM and dynein have roles in tethering dynamic microtubules and maintaining synaptic density in cortical neurons PMID: 23960070
    4. Both P-TEFb recruitment to the HIV long terminal repeat and enhanced HIV processivity were blocked by ERK inhibitor, but not by AKT and PI3K inhibitors. PMID: 21763495
    5. the mRNA expression level of DYNC1I1 were significantly up-regulated in tumorous liver tissues compared with corresponding nontumorous counterparts. PMID: 21767414
    6. NDE1 and NDEL1 act upstream of LIS1 in dynein recruitment, and/or activation, on the membrane. PMID: 20048338
    7. identification of a novel 24-kDa protein that binds directly to dynein intermediate chain [PLAC-24] PMID: 12006665

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族:
    Dynein intermediate chain family
  • 數據庫鏈接:

    HGNC: 2963

    OMIM: 603772

    KEGG: hsa:1780

    STRING: 9606.ENSP00000320130

    UniGene: Hs.440364



主站蜘蛛池模板: 欧美顶级少妇作爱| 2018高清国产一区二区三区| 少妇激情艳情综合小视频| 麻花传媒在线mv免费观看视频 | 中文字幕奈奈美被公侵犯| 国产99在线 | 中国| 国产av一区二区三区最新精品| 亚洲精品亚洲人成在线| 亚洲精品国产情侣av在线| 国产制服丝袜欧美在线观看| 沈阳45老熟女高潮喷水亮点| 免费观看18禁无遮挡真人网站| 亚洲旡码a∨一区二区三区| 亚洲另类欧美综合久久图片区| 欧洲熟妇精品视频| 国产精品宾馆精品酒店| 天堂在线最新版www中文| 亚洲欧洲日产国无高清码图片 | 黑人巨茎大战俄罗斯美女| 西西人体大胆啪啪实拍| 国产午夜鲁丝片av无码| 无码毛片视频一区二区本码 | 人妻熟女av一区二区三区| 韩国主播av福利一区二区| 日韩精品久久无码人妻中文字幕| 又色又污又爽又黄的网站| 2018高清日本一道国产-在| 中文字幕无线码中文字幕免费| 四虎成人精品国产永久免费无码| 国产在线高清理伦片a| 少妇无码av无码去区钱| 精品少妇无码av无码专区| 亚洲综合精品伊人久久| 国语对白嫖老妇胖老太| 久久婷婷香蕉热狠狠综合| 午夜时刻免费入口| 亚色九九九全国免费视频| 色老头在线一区二区三区| 国产av综合影院| 亚洲综合精品成人| 亚洲第一页综合图片自拍|