在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Cytohesin-1 (CYTH1)

Recombinant Human Cytohesin-1 (CYTH1)

  • 中文名稱：
    Recombinant Human Cytohesin-1(CYTH1)
  • 貨號：
    CSB-YP620880HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Cytohesin-1(CYTH1)
  • 貨號：
    CSB-EP620880HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Cytohesin-1(CYTH1)
  • 貨號：
    CSB-EP620880HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Cytohesin-1(CYTH1)
  • 貨號：
    CSB-BP620880HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Cytohesin-1(CYTH1)
  • 貨號：
    CSB-MP620880HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    B2 1; CLM1; CTH 1; CYH1_HUMAN; CYTH1; CYTIP; Cytoadhesin 1; CYTOHESIN 1; Cytohesin-1; D17S811E; FLJ34050; FLJ41900; Homolog of secretory protein SEC7; KIAA4240; mKIAA4240; mSec7 1; OTTHUMP00000196778; OTTHUMP00000196779; PH; PH; SEC7 and coiled-coil domain containing protein 1; Pleckstrin homology Sec7 and coiled/coil domains 1 ; Pleckstrin homology Sec7 and coiled/coil domains protein 1; Pleckstrin homology; Sec7 and coiled coil domains 1; PSCD1; SEC7 and coiled-coil domain-containing protein 1; Sec7; SEC7 homolog A; SEC7 homolog B2 1; SEC7 homolog B2-1; SEC7; yeast; homolog of; Sec7a
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-398
  • 氨基酸序列
    MEEDDSYVPS DLTAEERQEL ENIRRRKQEL LADIQRLKDE IAEVANEIEN LGSTEERKNM QRNKQVAMGR KKFNMDPKKG IQFLIENDLL KNTCEDIAQF LYKGEGLNKT AIGDYLGERD EFNIQVLHAF VELHEFTDLN LVQALRQFLW SFRLPGEAQK IDRMMEAFAQ RYCQCNNGVF QSTDTCYVLS FAIIMLNTSL HNPNVKDKPT VERFIAMNRG INDGGDLPEE LLRNLYESIK NEPFKIPEDD GNDLTHTFFN PDREGWLLKL GGGRVKTWKR RWFILTDNCL YYFEYTTDKE PRGIIPLENL SIREVEDSKK PNCFELYIPD NKDQVIKACK TEADGRVVEG NHTVYRISAP TPEEKEEWIK CIKAAISRDP FYEMLAARKK KVSSTKRH
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.
  • 基因功能參考文獻：
    1. computational study suggests that although curcumin to some extent binds with Tp receptor, yet the inhibition of Arf6GDP to Arf6GTP conversion appeared to be an important mechanism by which curcumin inhibits U46619-induced increase in PLD activity in PASMCs. PMID: 28780751
    2. CYTH1 is a novel major regulator of adhesion and engraftment in human hematopoietic stem and progenitor cells through mechanisms that, at least in part, involve the activation of integrins. PMID: 27899358
    3. FRMD4A RNAi or inhibition of cytohesins strongly upregulated secretion of endogenous tau. These results suggest that FRMD4A, a genetic risk factor for late-onset Alzheimer's disease, regulates tau secretion by activating cytohesin-Arf6 signaling. PMID: 27044754
    4. cytohesin inhibition has an antiproliferative effect in gefitinib-resistant lung cancer cells PMID: 22815959
    5. findings suggest that cytohesin-1 is a key regulator of neutrophil adhesion to endothelial cells and to components of extracellular matrix, which may influence cell emigration through its dual opposing effect on beta2 and beta1 integrin activation PMID: 21511340
    6. involvement of cytohesin-1 in the regulation of the functional responses of human PMNs, linked, in part at least, to the activation of Arf6. PMID: 20018626
    7. Data show that CYTIP and cytoadhesin-1 are upregulated during dendritic cell maturation. PMID: 12606567
    8. findings reveal that mycobacteria promote their uptake through a process of "inside-out" signaling involving CD14, TLR2, PI3K, and cytohesin-1. This converts low avidity CR3 into an active receptor leading to increased bacterial internalization PMID: 15778383
    9. demonstrate an essential role of cytohesin-1/RhoA during ameboid migration in the presence of integrins PMID: 19346499
    10. Phosphorylated cytohesin-1 is able to tightly associate with the actin cytoskeleton, and is required for maximal leukocyte function antigen-1-mediated adhesion of Jurkat cells to Icam-1. PMID: 11438522

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Cell junction, tight junction. Cell junction, adherens junction.
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 9501

    OMIM: 182115

    KEGG: hsa:9267

    STRING: 9606.ENSP00000354398

    UniGene: Hs.191215



主站蜘蛛池模板： 国产精品久久久国产盗摄| 在线欧美中文字幕农村电影| 精品人妻人人做人人爽| 成年女人免费v片| 亚洲无人区午夜福利码高清完整版| 高清国产在线拍揄自揄视频| 欧洲美熟女乱又伦| 国产又色又爽无遮挡免费动态图 | 香蕉影院在线观看| 国产精品久久久久久成人影院| 伦理片无码电影在线看| 99re在线播放| 精品少妇人妻av免费久久久| 精品国产杨幂在线观看| 午夜嘿嘿嘿在线观看| 华人少妇被黑人粗大的猛烈进| 美女裸体色黄污视频网站| 色婷婷综合和线在线| 综合色一色综合久久网| 成人网站在线进入爽爽爽| 免费大片黄在线观看| 两根大肉大捧一进一出好爽视频| 色欲色香天天天综合网站| 丰满岳乱妇久久久| 女人被黑人狂躁c到高潮小说| 柠檬福利精品视频导航| 国产乱人伦偷精品视频下| 初尝黑人嗷嗷叫中文字幕| 动漫精品啪啪一区二区三区| 天天爽天天摸天天碰| 中文天堂最新版资源www官网| 在线亚洲人成电影网站色www| 人妻丰满熟妇无码区免费| 成人自慰女黄网站免费大全| 国产大片黄在线观看私人影院| 无码av中文字幕久久专区| 国产成人欧美亚洲日韩电影| 欧美大香线蕉线伊人久久| 中文字幕精品亚洲无线码一区| 欧美激情乱人伦| 日本老熟妇乱子伦视频|