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  4. Recombinant Human Cytochrome P450 26C1 (CYP26C1), partial

Recombinant Human Cytochrome P450 26C1 (CYP26C1), partial

  • 中文名稱：
    Recombinant Human Cytochrome P450 26C1(CYP26C1),partial
  • 貨號：
    CSB-YP751026HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Cytochrome P450 26C1(CYP26C1),partial
  • 貨號：
    CSB-EP751026HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Cytochrome P450 26C1(CYP26C1),partial
  • 貨號：
    CSB-EP751026HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Cytochrome P450 26C1(CYP26C1),partial
  • 貨號：
    CSB-BP751026HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Cytochrome P450 26C1(CYP26C1),partial
  • 貨號：
    CSB-MP751026HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CYP26C1
  • Uniprot No.：
  • 別名：
    CP26C_HUMAN; cyp26b1l; CYP26C1; cyp26d1; Cytochrome P450 26C1; Cytochrome P450 family 26 subfamily C polypeptide 1; Cytochrome P450; subfamily XXVIC polypeptide 1; EG546726; FFDD4; FLJ45301; MGC158120; retinoic acid catabolizing enzyme
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).
  • 基因功能參考文獻：
    1. Together, these findings describe CYP26C1 as the first genetic modifier for SHOX deficiency. PMID: 27861128
    2. Elevated expression of CYP26C1 in primary breast carcinomas PMID: 26009309
    3. Focal facial dermal dysplasia, type IV results from the loss of function mutations in CYP26C1. PMID: 23161670
    4. CYP26A1 and CYP26C1 play a pivotal role in the pathogenesis of nonsyndromic bilateral and unilateral optic nerve aplasia. PMID: 21850183
    5. may play a specific role in catabolizing both all-trans and 9-cis isomers of retinoic acid. PMID: 14532297
    6. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
    7. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 19703508
    8. Observational study of gene-disease association. (HuGE Navigator) PMID: 16933217

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  • 相關疾病：
    Focal facial dermal dysplasia 4 (FFDD4)
  • 亞細胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 組織特異性：
    Detected in most tissues at very low level.
  • 數據庫鏈接：

    HGNC: 20577

    OMIM: 608428

    KEGG: hsa:340665

    STRING: 9606.ENSP00000285949

    UniGene: Hs.369993



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