在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cyclin-dependent kinase 19 (CDK19)

  • 中文名稱:
    Recombinant Human Cyclin-dependent kinase 19(CDK19)
  • 貨號:
    CSB-YP887142HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-dependent kinase 19(CDK19)
  • 貨號:
    CSB-EP887142HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-dependent kinase 19(CDK19)
  • 貨號:
    CSB-EP887142HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-dependent kinase 19(CDK19)
  • 貨號:
    CSB-BP887142HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-dependent kinase 19(CDK19)
  • 貨號:
    CSB-MP887142HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CDK19
  • Uniprot No.:
  • 別名:
    bA346C16.3; CDC2 related protein kinase 6; CDC2-related protein kinase 6; CDC2L6; CDK11; Cdk19; CDK19_HUMAN; CDK8 like cyclin dependent kinase; Cell division cycle 2 like 6 (CDK8 like); Cell division cycle 2 like protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; Cyclin dependent kinase (CDC2 like) 11; Cyclin dependent kinase 11; Cyclin dependent kinase 19 variant 2; Cyclin-dependent kinase 11; Cyclin-dependent kinase 19; Death preventing kinase; Death-preventing kinase; KIAA1028
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-502
  • 氨基酸序列
    MDYDFKAKLA AERERVEDLF EYEGCKVGRG TYGHVYKARR KDGKDEKEYA LKQIEGTGIS MSACREIALL RELKHPNVIA LQKVFLSHSD RKVWLLFDYA EHDLWHIIKF HRASKANKKP MQLPRSMVKS LLYQILDGIH YLHANWVLHR DLKPANILVM GEGPERGRVK IADMGFARLF NSPLKPLADL DPVVVTFWYR APELLLGARH YTKAIDIWAI GCIFAELLTS EPIFHCRQED IKTSNPFHHD QLDRIFSVMG FPADKDWEDI RKMPEYPTLQ KDFRRTTYAN SSLIKYMEKH KVKPDSKVFL LLQKLLTMDP TKRITSEQAL QDPYFQEDPL PTLDVFAGCQ IPYPKREFLN EDDPEEKGDK NQQQQQNQHQ QPTAPPQQAA APPQAPPPQQ NSTQTNGTAG GAGAGVGGTG AGLQHSQDSS LNQVPPNKKP RLGPSGANSG GPVMPSDYQH SSSRLNYQSS VQGSSQSQST LGYSSSSQQS SQYHPSHQAH RY
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Genes coregulated by CDK8/19 and NFkappaB include IL8, CXCL1, and CXCL2. PMID: 28855340
    2. Moreover, it identified CDK19 and CDK8 to be specifically overexpressed during prostate cancer progression, highlighting their potential as novel therapeutic targets in advanced prostate cancer. PMID: 27678455
    3. High CDK19 expression is associated with osteosarcoma. PMID: 28416637
    4. On stimulation of TLR9, CDK8/19 positively regulates inflammatory gene transcription in cooperation with NF-kappaB and C/EBPbeta. PMID: 28151579
    5. Data suggest that, during neurogenesis, Mediator complex cyclin-dependent kinases (CDK8, CDK19) interact directly with PRC2 (polycomb repressive complex 2) subunit EZH2 (enhancer of zeste homolog 2), as well as SUZ12 (suppressor of zeste 12 homolog). PMID: 26002960
    6. Mediator-associated kinases CDK8 and CDK19 restrain increased activation of key super-enhancer-associated genes in acute myeloid leukaemia (AML) cells PMID: 26416749
    7. Microarrays identified target genes for each CDK, and we selected six genes: two target genes of CDK8, two target genes of CDK19 and two genes that were targets for both. PMID: 22117896
    8. CDK8 and CDK19, individually interact with PRMT5 and WDR77, and their interactions with PRMT5 cause transcriptional repression of C/EBPbeta target genes. PMID: 23749998
    9. plays a role in mechanisms of transcriptional regulation upon protein phosphorylation. (review) PMID: 20408451

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, perinuclear region. Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
  • 數據庫鏈接:

    HGNC: 19338

    OMIM: 614720

    KEGG: hsa:23097

    STRING: 9606.ENSP00000357907

    UniGene: Hs.744895



主站蜘蛛池模板: 中文无码成人免费视频在线观看| 午夜亚洲福利在线老司机| 精品国产一区二区三区av 性色| 欧洲美熟女乱又伦av影片| 成人美女黄网站色大色费全看| 亚洲人成电影网站在线播放| 小鲜肉自慰网站| 波多野结衣 黑人| 亚洲精品一区二区三区麻豆| 中文字幕精品亚洲人成在线| 国模吧无码一区二区三区| 欧美老熟妇喷水| 午夜伦4480yy私人影院久久| 欧美精品videosbestsex日本| 人妻丰满熟妇av无码区免| 亚洲一区激情校园小说| 国产成人a∨麻豆精品| 人妻少妇精品一区二区三区| 无码人妻av一二区二区三区| 久久熟妇人妻午夜寂寞影院| 夜夜高潮夜夜爽高清视频| 国产日韩av免费无码一区二区三区 | 天天摸夜夜添夜夜无码| 朝鲜女人大白屁股ass| 国产精品a国产精品a手机版| 暴力强奷在线播放无码| 麻豆精品一区二区综合av| 日日碰狠狠躁久久躁2023| 天天天天噜在线视频| 久久偷看各类wc女厕嘘嘘| 人妻少妇heyzo无码专区| 女狠狠噜天天噜日日噜| 精品人无码一区二区三区 | 无码视频一区二区三区在线观看 | 日产精品高潮呻吟av久久| 韩国国内大量揄拍精品视频| 亚洲美女又黄又爽在线观看 | 亚洲欧洲日产国码无码| 色婷婷美国农夫综合激情亚洲| 精品久久久久久无码人妻蜜桃| 久久久久欧美精品观看|