在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cyclin-T2 (CCNT2)

  • 中文名稱:
    Recombinant Human Cyclin-T2(CCNT2)
  • 貨號:
    CSB-YP004833HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-T2(CCNT2)
  • 貨號:
    CSB-EP004833HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-T2(CCNT2)
  • 貨號:
    CSB-EP004833HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-T2(CCNT2)
  • 貨號:
    CSB-BP004833HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-T2(CCNT2)
  • 貨號:
    CSB-MP004833HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CCNT2
  • Uniprot No.:
  • 別名:
    CCNT2; CCNT2_HUMAN; Cyclin T2a; Cyclin T2b; Cyclin-T2; CycT2; FLJ90560; MGC134840; SDS stable vimentin bound DNA fragment HEF42VIM22; Subunit of positive elongation transcription factor b
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-730
  • 氨基酸序列
    MASGRGASSR WFFTREQLEN TPSRRCGVEA DKELSCRQQA ANLIQEMGQR LNVSQLTINT AIVYMHRFYM HHSFTKFNKN IISSTALFLA AKVEEQARKL EHVIKVAHAC LHPLEPLLDT KCDAYLQQTQ ELVILETIML QTLGFEITIE HPHTDVVKCT QLVRASKDLA QTSYFMATNS LHLTTFCLQY KPTVIACVCI HLACKWSNWE IPVSTDGKHW WEYVDPTVTL ELLDELTHEF LQILEKTPNR LKKIRNWRAN QAARKPKVDG QVSETPLLGS SLVQNSILVD SVTGVPTNPS FQKPSTSAFP APVPLNSGNI SVQDSHTSDN LSMLATGMPS TSYGLSSHQE WPQHQDSART EQLYSQKQET SLSGSQYNIN FQQGPSISLH SGLHHRPDKI SDHSSVKQEY THKAGSSKHH GPISTTPGII PQKMSLDKYR EKRKLETLDL DVRDHYIAAQ VEQQHKQGQS QAASSSSVTS PIKMKIPIAN TEKYMADKKE KSGSLKLRIP IPPTDKSASK EELKMKIKVS SSERHSSSDE GSGKSKHSSP HISRDHKEKH KEHPSSRHHT SSHKHSHSHS GSSSGGSKHS ADGIPPTVLR SPVGLSSDGI SSSSSSSRKR LHVNDASHNH HSKMSKSSKS SGSSSSSSSS VKQYISSHNS VFNHPLPPPP PVTYQVGYGH LSTLVKLDKK PVETNGPDAN HEYSTSSQHM DYKDTFDMLD SLLSAQGMNM
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). The activity of this complex is regulated by binding with 7SK snRNA. Plays a role during muscle differentiation; P-TEFB complex interacts with MYOD1; this tripartite complex promotes the transcriptional activity of MYOD1 through its CDK9-mediated phosphorylation and binds the chromatin of promoters and enhancers of muscle-specific genes; this event correlates with hyperphosphorylation of the CTD domain of RNA pol II. In addition, enhances MYOD1-dependent transcription through interaction with PKN1. Involved in early embryo development.; (Microbial infection) Promotes transcriptional activation of early and late herpes simplex virus 1/HHV-1 promoters.
  • 基因功能參考文獻:
    1. miR-192 inhibits cell proliferation and induces G0/G1 cell cycle arrest in AML by regulating the expression of CCNT2. PMID: 28409330
    2. interaction with pRb PMID: 12037672
    3. CycT2 not only contains two domains that target rna polymerase II but this substrate recognition is necessary for its transcriptional activity via DNA PMID: 15563843
    4. Data strengthen the hypothesis that Cyclin T2a plays a role in muscle differentiation, and propose PKNalpha as a novel partner of Cyclin T2a in this process. PMID: 16331689
    5. The results establish that cdk9/cyclin T2a-mediated coactivation of MyoD depends on serine 37 phosphorylation. PMID: 16841087

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, perinuclear region. Nucleus.
  • 蛋白家族:
    Cyclin family, Cyclin C subfamily
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 1600

    OMIM: 603862

    KEGG: hsa:905

    STRING: 9606.ENSP00000264157

    UniGene: Hs.744115



主站蜘蛛池模板: 国产在线视频一区二区三区98 | 亚洲精品无码久久久久秋霞 | 亚洲国产成人精品无码区在线软件| 国产女厕所盗摄老师厕所嘘嘘 | 亚洲 欧洲 日韩 综合在线| 无遮无挡爽爽免费毛片| 人妻人人看人妻人人添| 狠狠色噜噜狠狠色综合久| 久久婷婷五月综合97色| 综合欧美日韩国产成人| 荫蒂被男人添的好舒服爽免费视频| 国产超碰人人爽人人做av| 解开人妻的裙子猛烈进入| 欧美无遮挡很黄裸交视频| 亚洲午夜无码久久久久小说| 在线永久免费观看黄网站| 国产亚洲综合区成人国产系列| 欧美国产日韩a在线视频| 国产亚洲精品资源在线26u| 麻豆视传媒精品av| 亚洲欧美日韩成人高清在线一区| 精品国产人妻一区二区三区| 亚洲免费视频免在线观看| 乱码视频午夜间在线观看| 92电影网午夜福利| 在线中文字幕亚洲日韩2020| 国产欧美日韩另类在线专区| 高大丰满熟妇丰满的大白屁股| 亚洲熟女综合色一区二区三区| 污18禁污色黄网站免费| 日韩综合无码一区二区| 纯爱无遮挡h肉动漫在线播放| 无码一区18禁3d| 女人张开腿让男桶喷水高潮| 亚洲无人区一区二区三区| 亚洲国产成人精品无码区在线观看| 人妻在客厅被c的呻吟| 午夜三级a三级三点在线观看| 青青草无码免费一二三区| 窝窝午夜精品一区二区| 无码人妻av免费一区二区三区|