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Recombinant Human Cyclin-I (CCNI)

  • 中文名稱:
    Recombinant Human Cyclin-I(CCNI)
  • 貨號:
    CSB-YP623898HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-I(CCNI)
  • 貨號:
    CSB-EP623898HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-I(CCNI)
  • 貨號:
    CSB-EP623898HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-I(CCNI)
  • 貨號:
    CSB-BP623898HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Cyclin-I(CCNI)
  • 貨號:
    CSB-MP623898HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CCNI
  • Uniprot No.:
  • 別名:
    CCNI; Cyclin-I
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-377
  • 氨基酸序列
    MKFPGPLENQ RLSFLLEKAI TREAQMWKVN VRKMPSNQNV SPSQRDEVIQ WLAKLKYQFN LYPETFALAS SLLDRFLATV KAHPKYLSCI AISCFFLAAK TVEEDERIPV LKVLARDSFC GCSSSEILRM ERIILDKLNW DLHTATPLDF LHIFHAIAVS TRPQLLFSLP KLSPSQHLAV LTKQLLHCMA CNQLLQFRGS MLALAMVSLE MEKLIPDWLS LTIELLQKAQ MDSSQLIHCR ELVAHHLSTL QSSLPLNSVY VYRPLKHTLV TCDKGVFRLH PSSVPGPDFS KDNSKPEVPV RGTAAFYHHL PAASGCKQTS TKRKVEEMEV DDFYDGIKRL YNEDNVSENV GSVCGTDLSR QEGHASPCPP LQPVSVM
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. A cyclin I-Cdk5 complex forms a critical antiapoptotic factor in the process of generating cisplatin resistance in cervical cancer. PMID: 26698249
    2. Knockdown of Cyclin I induced cell cycle arrest at S/G2/M phases. PMID: 23907122
    3. The increased levels of cyclin I and GDI2 found to be associated with pancreatic carcinoma were further confirmed by Western blot analyses in an independent series of serum samples and/or pancreatic juice samples PMID: 17507299
  • 亞細胞定位:
    Nucleus membrane.
  • 蛋白家族:
    Cyclin family
  • 組織特異性:
    Highest levels in adult heart, brain and skeletal muscle. Lower levels in adult placenta, lung, kidney and pancreas. Also high levels in fetal brain and lower levels in fetal lung, liver and kidney. Also abundant in testis and thyroid.
  • 數據庫鏈接:

    HGNC: 1595

    KEGG: hsa:10983

    STRING: 9606.ENSP00000237654

    UniGene: Hs.518827



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