在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Coronin-1B (CORO1B)

  • 中文名稱:
    Recombinant Human Coronin-1B(CORO1B)
  • 貨號:
    CSB-YP880087HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Coronin-1B(CORO1B)
  • 貨號:
    CSB-EP880087HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Coronin-1B(CORO1B)
  • 貨號:
    CSB-EP880087HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Coronin-1B(CORO1B)
  • 貨號:
    CSB-BP880087HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Coronin-1B(CORO1B)
  • 貨號:
    CSB-MP880087HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CORO1B
  • Uniprot No.:
  • 別名:
    COR1B_HUMAN; CORO 1B; CORO1B; Coronin 1B; Coronin 2; Coronin actin binding protein 1B; Coronin-1B; Coronin-2; Coronin1B; Coronin2; DKFZP762I166; OTTHUMP00000236823
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-489
  • 氨基酸序列
    MSFRKVVRQS KFRHVFGQPV KNDQCYEDIR VSRVTWDSTF CAVNPKFLAV IVEASGGGAF LVLPLSKTGR IDKAYPTVCG HTGPVLDIDW CPHNDEVIAS GSEDCTVMVW QIPENGLTSP LTEPVVVLEG HTKRVGIIAW HPTARNVLLS AGCDNVVLIW NVGTAEELYR LDSLHPDLIY NVSWNHNGSL FCSACKDKSV RIIDPRRGTL VAEREKAHEG ARPMRAIFLA DGKVFTTGFS RMSERQLALW DPENLEEPMA LQELDSSNGA LLPFYDPDTS VVYVCGKGDS SIRYFEITEE PPYIHFLNTF TSKEPQRGMG SMPKRGLEVS KCEIARFYKL HERKCEPIVM TVPRKSDLFQ DDLYPDTAGP EAALEAEEWV SGRDADPILI SLREAYVPSK QRDLKISRRN VLSDSRPAMA PGSSHLGAPA STTTAADATP SGSLARAGEA GKLEEVMQEL RALRALVKEQ GDRICRLEEQ LGRMENGDA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
  • 基因功能參考文獻:
    1. VEGF-activated p38alpha phosphorylates coronin 1B at Ser2 and activates the Arp2/3 complex by liberating it from coronin 1B. PMID: 27592029
    2. Coronin 1B constitutively binds to TGF beta receptor I in vascular smooth muscle cells. PMID: 28625921
    3. The loss of junctional NMIIA, upon Coronin 1B knockdown, perturbed RhoA signaling. PMID: 27650961
    4. When cells undergo apoptosis in an epithelial monolayer, coronin 1B is recruited to the junctional cortex at apoptotic/neighbor cell interface in an E-cadherin-dependent fashion to support actin architectural reorganization, contractility, and extrusion. PMID: 27046832
    5. Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis. PMID: 23667561
    6. analysis of the mechanism for negatively regulating Rho-kinase (ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility PMID: 22563075
    7. Coronin 1B regulates leading edge dynamics and controls cell motility and interactions with the actin-related protein (Arp)2/3 complex PMID: 16027158
    8. Study concludes that Coronin 1B's coordination of filament formation by Arp2/3 complex and filament turnover by Cofilin is required for effective lamellipodial protrusion and cell migration. PMID: 17350576
    9. In rabbits, cholinergic stimulation increases the phosphorylation of coronin 1B in gastric mucosal cells PMID: 9915840

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.
  • 蛋白家族:
    WD repeat coronin family
  • 數據庫鏈接:

    HGNC: 2253

    OMIM: 609849

    KEGG: hsa:57175

    STRING: 9606.ENSP00000340211

    UniGene: Hs.6191



主站蜘蛛池模板: 免费人成视频x8x8| 国产av巨作丝袜秘书| 蜜芽av无码精品国产午夜| 蜜桃av蜜臀av色欲av麻| 欧美噜噜久久久xxx| 97久久国产亚洲精品超碰热| 无遮挡呻吟娇喘视频免费播放| 婷婷丁香五月天综合东京热| 色欲网天天无码av| 少妇人妻邻居| 人妻丰满熟妇av无码区不卡| 欧美506070老妇乱子伦| 99热成人精品国产免费 | 久久精品人人做人人爽| 黄a大片av永久免费| 强奷人妻日本中文字幕| 亚洲人成电影网站色| 一区一区三区产品乱码亚洲| 人人妻人人澡av天堂香蕉| 国产99久久久国产精品~~牛| 日本黄网站三级三级三级| 日韩做a爰片久久毛片a片| 国产成人涩涩涩视频在线观看| 三男一女吃奶添下面视频| 亚洲国产欧美国产综合久久| 国产精品992tv在线观看| 国产精品亚洲二区在线观看| 亚洲经典三级| 一本大道久久东京热av| 丰满少妇做爰视频爽爽和| 亚瑟国产精品久久| 亚洲妇女无套内射精| 国产成人最新三级在线视频| 伊人久久亚洲综合影院首页| 强行糟蹋人妻hd中文字| 亚洲中文字幕永久在线全国| 精品一区二区成人精品| 蜜桃臀无码内射一区二区三区 | 国产三级av在线播放| 区二区三区玖玖玖| 人人人插人人费|