在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Contactin-2 (CNTN2 AXT TAG1 TAX1)

  • 中文名稱:
  • 貨號:
    CSB-YP733782HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP733782HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP733782HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-BP733782HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-MP733782HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CNTN2
  • Uniprot No.:
  • 別名:
    Contactin-2; Axonal glycoprotein TAG-1; Axonin-1; Transient axonal glycoprotein 1; TAX-1; CNTN2 AXT TAG1 TAX1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion.
  • 基因功能參考文獻:
    1. the selective distribution of Caspr2 and TAG-1 may be regulated, allowing them to modulate the strategic function of the Kv1 complex along axons PMID: 28533267
    2. the ectodomains of CNTNAP2 and contactin 2 (CNTN2) bind directly and specifically, with low nanomolar affinity. PMID: 27621318
    3. RACK1 interacts with CNTN2, and the effects of RACK1 on glioma cell growth and differentiation are mediated by CNTN2. PMID: 26718491
    4. Our results clearly demonstrate that mouse and human contactin-2 are physiological substrates for BACE1 PMID: 24405708
    5. A single nucleotide deletion in exon 6 of CNTN2 results in a frameshift mutation, segregating in a recessive manner in a consanguineous Egyptian family with epilepsy. PMID: 23518707
    6. The single-nucleotide polymorphism (SNP) rs2275697 in the TAG-) gene was not associated with treatment responsiveness, treatment dependence, disability, or mortality in chronic inflammatory demyelinating polyneuropathy PMID: 22462668
    7. allelic variation in TAG-1 does not play a major role in determining multifocal motor neuropathy susceptibility. PMID: 22003931
    8. single nucleotide polymorphisms in TAG-1 are related to the IVIg responsiveness of Chronic inflammatory demyelinating polyneuropathy patients. PMID: 21696500
    9. The domains responsible for the neurite outgrowth promoting activity of TAG-1 have been investigated as well as its interactions with other cell adhesion molecules. PMID: 12139915
    10. TAG-1 homophilic interaction is based on dimer formation rather than formation of a molecular zipper as proposed for the chicken ortholog. PMID: 17766378
    11. Contactin-2 is expressed by various neuronal populations and sequestered in the juxtaparanodal domain of myelinated axons both at the axonal and myelin sides; is an autoantigen targeted by T cells and autoantibodies in MS. PMID: 19416878
    12. immune response to CNTN2 and possible involvement in multiple sclerosis and EAE [REVIEW] PMID: 19451620

    顯示更多

    收起更多

  • 相關疾病:
    Epilepsy, familial adult myoclonic, 5 (FAME5)
  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.
  • 蛋白家族:
    Immunoglobulin superfamily, Contactin family
  • 數據庫鏈接:

    HGNC: 2172

    OMIM: 190197

    KEGG: hsa:6900

    STRING: 9606.ENSP00000330633

    UniGene: Hs.519220



主站蜘蛛池模板: 国产亚州精品女人久久久久久 | 国产精品久久久久7777| 88国产精品欧美一区二区三区| 久久久亚洲欧洲日产国码606| 国产成人精品午夜福利在线观看| 精品乱码无人区一区二区| 爆乳护士一区二区三区在线播放 | 亚洲国产成人av网站| 欧美黑人性暴力猛交喷水| 人妻无码av中文系列久| 老司机在线精品视频播放| 国产不卡视频一区二区三区| 巨胸美乳无码人妻视频| 在线高清理伦片a| 成人麻豆亚洲综合无码精品| 亚洲精品无码少妇30p| 西西人体444www高清大胆| 内射老妇bbwx0c0ck| 国产av夜夜欢一区二区三区| 亚 洲 成 人 网站在线观看| 成人免费午夜无码视频| 欧美人和黑人牲交网站上线| 欧美s码亚洲码精品m码| 337p粉嫩日本欧洲亚洲大胆| 亚洲精品一区二区玖玖爱| 曰的好深好爽免费视频网站| 免费一区二区无码东京热| 中文字幕人妻无码系列第三区| 久久99精品久久久久婷婷| 国产极品美女到高潮无套| 国产爽视频在线观看视频| 少妇被粗大的猛烈进出视频| 亚洲成av人片久久| 夜色福利院在线观看免费| 国产亚洲tv在线观看| 国产精品一区二区高清在线| 欧美影院成年免费版| 无码一区二区波多野结衣播放搜索 | 久久人妻少妇嫩草av蜜桃| 少妇仑乱a毛片无码| 亚洲另类欧美综合久久图片区|