在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Collagen alpha-1 (XV) chain (COL15A1), partial

In Stock
  • 貨號:
    CSB-EP005722HU
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    COL15A1
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    26.5 kDa
  • 表達(dá)區(qū)域:
    40-228aa
  • 氨基酸序列
    HLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.; Restin potently inhibits angiogenesis.
  • 基因功能參考文獻(xiàn):
    1. COL15A1 mRNA was up-regulated in hepatocellular cancer (HCC) and collagen XV was expressed along the sinusoid-like endothelium of HCC but not in non-tumoral regions, which implies that collagen XV contributes to the capillarization of HCC. PMID: 26293333
    2. This study demonstrated that novel role for collagen XV in motor axon pathfinding and neuromuscular development. PMID: 26937007
    3. we identified an epithelial ovarian cancer susceptibility loci at 9q22.33 (rs1413299 in COL15A1, P(meta) = 1.88 x 10(-8)) PMID: 25134534
    4. The obtained results indicate that the changes in gene expression in bone marrow progenitor cells can be involved into space flight-induced osteopenia. PMID: 25509878
    5. COL15A1, provide evidence for concomitant epigenetic regulation and genetic susceptibility, and define a class of causal targets that sit at the intersection of genetic and epigenetic predisposition in the etiology of complex disease. PMID: 23912340
    6. These results suggest genetic variation in COL15A1 and COL18A1 can modify the age of onset of both early and late onset POAG. PMID: 23621901
    7. Collagen type XV and osteocalcin expression are highly sensitive markers to extracellular calcium PMID: 22034088
    8. the crystal structure of the trimerization domain of human type XV collagen PMID: 20932905
    9. type XV and XVIII collagens are expressed in specialized basement membranes. PMID: 11937714
    10. Results show that the molecular structure of human tissue type XV presents a unique conformation among the collagens. PMID: 17355226
    11. the primary determinant is the gene specifying collagen XV, a proteoglycan closely associated with the basement membrane PMID: 18171981
    12. Polymorphisms in COL15 (collagen XV) gene are not associated with systemic sclerosis PMID: 18203317
    13. Data represent the first evidence of the expression of collagen type XV in human osteoblasts, a calcium-regulated protein which correlates to a specific functional state of these cells. PMID: 19365806

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Multiplexin collagen family
  • 組織特異性:
    Expressed predominantly in internal organs such as adrenal gland, pancreas and kidney.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 2192

    OMIM: 120325

    KEGG: hsa:1306

    STRING: 9606.ENSP00000364140

    UniGene: Hs.409034



主站蜘蛛池模板: 国产最新av在线播放不卡| 亚洲精品熟女国产| 国产精品人妻久久毛片高清无卡 | 国产精品日韩欧美一区二区三区| 非洲人与性动交ccoo| 高清粉嫩无套内谢国语播放| 久久精品亚洲乱码伦伦中文 | 亚洲高清最新av网站| 亚洲国精产品一二二线| 欧美肥婆性猛交xxxx| 无码帝国www无码专区色综合 | 亚洲日韩久久综合中文字幕| 亚洲男女羞羞无遮挡久久丫| 国产精品无码一区二区在线a片| 国产欧美国日产高清| 性色欲网站人妻丰满中文久久不卡| 免费观看18禁无遮挡真人网站 | 国产网红无码精品视频| 亚洲s码欧洲m码国产av| 337p亚洲日本中国大胆69| 巨乳美乳一区二区三区| 毛片免费视频肛交颜射免费视频 | 国产色xx群视频射精| 欧美 国产 日产 韩国 在线| 久久亚洲精品无码观看不卡| 精品香蕉99久久久久网站| 99久久人妻无码精品系列| 亚洲欧洲专线一区| 亚在线第一国产州精品99| 国产午夜片无码区在线观看| 国产成人精品久久亚洲高清不卡| 国产精品福利视频萌白酱| 日本三级欧美三级人妇视频 | 亚洲图片综合图区20p| 免费人成视频x8x8| 日产精品一区2区卡四卡二卡| 免费午夜理论不卡| 亚洲色欲综合一区二区三区| 日韩精品中文字幕无码专区 | 成人午夜特黄aaaaa片男男| 国产极品美女高潮无套在线观看 |