在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cold shock domain-containing protein E1 (CSDE1)

  • 中文名稱:
    Recombinant Human Cold shock domain-containing protein E1 (CSDE1)
  • 貨號:
    CSB-EP006040HU
  • 規格:
    ¥1536
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    N-ras upstream gene protein;Protein UNR
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    93.9 kDa
  • 表達區域:
    1-798aa
  • 氨基酸序列
    MSFDPNLLHNNGHNGYPNGTSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAVKLVKIKQEILPEERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRNGKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIPKVPSKNQNDPLPGRIKVDFVIPKELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDVRMFFHFSEILDGNQLHIADEVEFTVVPDMLSAQRNHAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQVATCVRLLGRNSNSKRLLGYVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKGKGNKVSAEKVNKTHSVNGITEEADPTIYSGKVIRPLRSVDPTQTEYQGMIEIVEEGDMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDGIELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAGVID
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules.; (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA.
  • 基因功能參考文獻:
    1. CSDE1 post-transcriptionally modulates core components of multiple regulatory nodes of human embryonic stem cell identity, neuroectoderm commitment and neurogenesis and acts as a negative regulator of neural differentiation and neurogenesis. PMID: 29129916
    2. UNR/CDSE1 expression is correlated with outcome in patients with resectable pancreatic ductal adenocarcinoma PMID: 28763470
    3. Results identify UNR as an oncogenic modulator of melanoma progression, unraveling the underlying molecular mechanisms. UNR seems to regulate translation elongation of Vimentin and RAC1 mRNAs. PMID: 27908735
    4. Studies indicate that Unr (upstream of N-ras) is post-translationally modified by phosphorylation and lysine acetylation. PMID: 26614667
    5. Hepsin suppressed CDK11p58 internal ribosome entry site activity in prostate cancer cells by modulating UNR expression and eIF-2alpha phosphorylation. PMID: 25576733
    6. Study suggests TRIM33 and NRAS-CSDE1 as candidate genes for autism, and may provide a novel insight into the etiology of autism PMID: 24189344
    7. unr and nPTB act as RNA chaperones by changing the structure of the IRES into one that permits translation initiation PMID: 12667457
    8. UNR translation is regulated by an internal ribosome entry site that is downregulated by polypyrimidine tract binding protein. PMID: 15928332
    9. regulation of IRES-mediated translation by hnRNP C1/C2 and Unr might be important in mitosis PMID: 17159903
    10. The data suggest that Unr acts as an RNA chaperone on rhinovirus RNA 5' UTR to maintain a complex tertiary internal ribosome entry site structure required for translational competency. PMID: 17947529

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body.
  • 數據庫鏈接:

    HGNC: 29905

    OMIM: 191510

    KEGG: hsa:7812

    STRING: 9606.ENSP00000407724

    UniGene: Hs.69855



主站蜘蛛池模板: 亚洲日韩a∨无码久| 国产精品a成v人在线播放| 女人被黑人躁得好爽视频| 无码高潮喷吹在线观看 | 国产又大又黑又粗免费视频| 国产男女免费完整视频网页| 国产女人18毛片水真多| 日韩综合夜夜香内射| 亚洲成色最大综合在线| 琪琪午夜理论片福利在线观看| 国产人成视频在线观看| 日本不卡高字幕在线2019| 国产精品女上位好爽在线| 中老年熟妇激情啪啪大屁股| 欧美大屁股熟妇bbbbbb| 波多野结衣一区二区三区高清av | 伊人久久大香线蕉精品| 永久免费观看国产裸体美女| 国产精品秘入口18禁麻豆免会员| 色伊人亚洲综合网站| 欧美精欧美乱码一二三四区 | 国色天香社区在线视频| 性色av蜜臀av色欲av| 日韩av无码国产精品| 免费国产精品视频在线| 自拍偷自拍亚洲精品情侣| 精品亚洲一区二区三区四区五区| 天堂va欧美va亚洲va好看va| 精品动漫一区二区无遮挡| 国产大屁股喷水视频在线观看| 久久熟妇人妻午夜寂寞影院| 国产亚洲精品自在久久蜜tv| 国产欧美一区二区精品久久久| 好大好湿好硬顶到了好爽视频| 国产乱人伦偷精品视频免| 欧美真人做爰在线观看| 欧妇女乱妇女乱视频| 亚洲精品综合在线影院| 男女啪啪永久免费网站| 亚洲精品乱码久久久久久不卡| 免费va国产高清大片在线|