在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Coagulation factor XIII B chain (F13B), partial

In Stock
  • 中文名稱:
    人F13B重組蛋白
  • 貨號:
    CSB-EP007922HU1
  • 規(guī)格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    (Fibrin-stabilizing factor B subunit)(Protein-glutamine gamma-glutamyltransferase B chain)(Transglutaminase B chain)
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    51.5 kDa
  • 表達(dá)區(qū)域:
    260-403aa
  • 氨基酸序列
    WYPESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGKWTEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGKWTLPPECVENNENCKHPPVVM
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin.
  • 基因功能參考文獻(xiàn):
    1. In VTE patients the changes of FXIII level and their effect on the risk of VTE show considerable sex-specific differences. Intron K polymorphism results in decreased FXIII levels, but does not influence the risk of VTE. PMID: 28865246
    2. The results suggest that plasma FXIII levels are subjected to multifactorial regulation with age, fibrinogen level and FXIII-B intron K polymorphism being the major determinants. Their effect on FXIII levels might influence the risk of thrombotic diseases. PMID: 27821352
    3. Genetic markers associated with low FXIIIB levels increase risk of ischemic stroke cardioembolic subtype. PMID: 26159793
    4. The FXIII-B intron K nt29756 G allele was associated with significant protection against CAS and MI in patients with a fibrinogen level in the upper tertile. PMID: 25569091
    5. Changes in plasma levels of FXIIIB are associated with cognitive decline in the elderly. PMID: 26088309
    6. Here, we update the knowledge about the pathophysiology of factor XIII deficiency and its therapeutic options. [review] PMID: 24503678
    7. Case Report: congenital FXIII-B deficiency in which alloantibodies developed to exogenous FXIII-B. PMID: 23407795
    8. FXIIIb subunit is found to be within normal range in eight Tunisian famillies with congenital factor XIII deficiency caused by two mutations, while expression of the FXIIIA subunit gene is decreased or undetectable. PMID: 19937244
    9. Develop ELISA/chemoluminescence assay demonstrating that FXIII-A and FXIII-B are low concentration components of tear proteome. PMID: 20079358
    10. role of FXIIIB in modifying catalytic activity of FXIIIA2 during factor XIII mediated crosslinking of fibrinogen PMID: 11816711
    11. F13 B subunit antigen may have a role in susceptibility to stroke based on this study of family members of patients in South Asia PMID: 15634282
    12. Genetic variants of factor XIIIb were evaluated on the effects of survival in myocardial infarction. PMID: 17515963
    13. at least 3 out of the 10 Sushi domains of FXIII-B have the distinct function of forming a homodimer and a heterotetramer, which should be ascribed to the differences in their amino acid sequences PMID: 18652485
    14. A specific colorimetric assay for measuring FXIIIB activity is reported. PMID: 19646949

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Factor XIII subunit B deficiency (FA13BD)
  • 亞細(xì)胞定位:
    Secreted.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 3534

    OMIM: 134580

    KEGG: hsa:2165

    STRING: 9606.ENSP00000356382

    UniGene: Hs.435782



主站蜘蛛池模板: 美女扒开屁股让男人桶| 国产一起色一起爱| 精精国产xxxx视频在线| 山东熟女啪啪哦哦叫| 久久婷婷五月综合色欧美蜜芽| 人人爽人人爽人人片a| 久久精品国产男包| 国产日产欧产精品品不卡| 日本视频高清一道一区| 久久午夜无码鲁丝片秋霞| 人妻少妇伦在线麻豆m电影| 亚洲国产成人一区二区三区| 野外少妇愉情中文字幕| 丝袜老师办公室里做好紧好爽| 毛茸茸厕所偷窥xxxx| 产后漂亮奶水人妻无码| 无码人妻人妻经典| 99久久综合狠狠综合久久| 无码国内精品久久人妻蜜桃| 高潮迭起av乳颜射后入| 中文字幕无码av波多野吉衣| 免费一本色道久久一区| 日99久9在线 | 免费| 熟妇人妻无码中文字幕| 99蜜桃臀久久久欧美精品网站| 国产爆乳无码视频在线观看 | 国产熟妇另类久久久久久| 亚洲国产日韩欧美综合a| 一 级 黄 色 片免费网站| av中文字幕潮喷人妻系列| a级大胆欧美人体大胆666| 日本成本人片免费网站| 国精产品999国精产| 精品系列无码一区二区三区| 亚洲国产精品隔壁老王| 亚洲熟女乱色综合亚洲图片| 精品麻豆国产色欲色欲色欲www| 国产 成人 综合 亚洲 网站| 亚洲毛片αv无线播放一区| 装睡被陌生人摸出水好爽| 超碰97人人做人人爱亚洲尤物|