在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Clathrin light chain A (CLTA)

  • 中文名稱:
    Recombinant Human Clathrin light chain A(CLTA)
  • 貨號:
    CSB-EP005591HU
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Clathrin light chain A; Clathrin light chain B; Clathrin light chain LCA; Clathrin light chain LCB; Clathrin light polypeptide A; Clathrin light polypeptide; Clathrin light polypeptide B; Clathrin light polypeptide LCA; Clathrin light polypeptide LCB; Clathrin; light chain (Lcb); Clathrin; light polypeptide (Lca); Clathrin; light polypeptide (Lcb); CLCA_HUMAN; CLTA; CLTB; Lca; LCB
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Isoform Non-brain
  • 來源:
    E.coli
  • 分子量:
    50.7kDa
  • 表達區(qū)域:
    1-218aa
  • 氨基酸序列
    MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge.
  • 基因功能參考文獻:
    1. Data indicate that clathrin-mediated endocytosis of proto-oncogene protein erbB-3 (ErbB3) is depending on epsin-1. PMID: 26975582
    2. Upon receptor activation, prostate alpha1A-adrenoceptors bind clathrin LCA. PMID: 23460120
    3. upon ligand activation, CysLT(1)R is tyrosine-phosphorylated and released from heterodimers with CysLT(2)R and, subsequently, internalizes from the plasma membrane to the nuclear membrane in a clathrin-, arrestin-3-, and Rab-5-dependent manner PMID: 21203429
    4. Data show that MAD2B interacts with CLTA during the G2/M phase of the cell cycle and that depletion of MAD2B leads to a marked increase in the percentage of misaligned chromosomes and a redistribution of CLTA during mitosis. PMID: 21152103
    5. Human Rhinovirus 2 uses clathrin-mediated endocytosis to infect cells PMID: 12692238
    6. Data suggest that clathrin heavy chains bound to light chains (LC) a and b contribute to pit formation, but the affinity of LCa-free HC in pits is reduced, and the Ca(2+)- and ATP-mediated control of clathrin function is lost. PMID: 16138905
    7. in mammalian cells CLCs function in intracellular membrane trafficking by acting as recruitment proteins for HIP1R, enabling HIP1R to regulate actin assembly on clathrin-coated structures PMID: 18165318

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族:
    Clathrin light chain family
  • 數據庫鏈接:

    HGNC: 2090

    OMIM: 118960

    KEGG: hsa:1211

    STRING: 9606.ENSP00000242285

    UniGene: Hs.522114



主站蜘蛛池模板: 国产成a人亚洲精品无码久久网| 99精品无人区乱码1区2区3区| 亚洲 丝袜 另类 校园 欧美| 少妇久久久久久久久久| 国产亚洲精品久久久美女18黄| 中文字幕无码精品亚洲资源网 | 亚洲精品国产精华液有哪些| 亚洲va在线va天堂va欧美va| 少妇群交换bd高清国语版| 国产suv精品一区二区四| 久章草国语自产拍在线观看| 野外被强j到高潮免费观看| 国产精品高清网站| 国产亚洲日韩欧美另类第八页| av无码人妻一区二区三区牛牛 | 瑜伽裤国产一区二区三区| 老司机久久精品最新免费| 亚洲精品少妇高清30p| 好吊色欧美一区二区三区四区| 麻豆精品国产精华精华液好用吗| 国产99视频精品免费视频36| 午夜亚洲国产理论片二级港台二级| 久久久久久久久久久久| 国产精品刮毛| 男女午夜猛烈啪啦啦视频| 精品国产一区二区三区无码| 性欧美老人牲交xxxxx视频| 国产亚洲精品久久久久久国| 99国产欧美另娄久久久精品| 久久国产成人午夜av影院| 换脸国产av一区二区三区| 蜜臀久久99精品久久久久久小说| 精品一区二区久久久久久久网站| 天天综合天天爱天天做| 另类亚洲综合区图片小说区| 人妻少妇av中文字幕乱码| 无码人妻久久一区二区三区蜜桃| 亚洲第一狼人天堂久久| av无码欧洲亚洲电影网| 国产成人精品无码专区| 先锋人妻无码av电影|