在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Clathrin interactor 1 (CLINT1)

Recombinant Human Clathrin interactor 1 (CLINT1)

  • 中文名稱：
    Recombinant Human Clathrin interactor 1(CLINT1)
  • 貨號：
    CSB-BP005552HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Clathrin interactor 1(CLINT1)
  • 貨號：
    CSB-EP005552HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Clathrin interactor 1(CLINT1)
  • 貨號：
    CSB-MP005552HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Name:CLINT1 Synonyms:ENTH, EPN4, EPNR, KIAA0171
  • Uniprot No.：
  • 別名：
    Clathrin interacting protein; Clathrin interactor 1; Clathrin-interacting protein localized in the trans-Golgi region; CLINT 1; Clint; CLINT1; ENTH; Enthoprotin; EPN4; EPN4_HUMAN; Epsin 4; Epsin related protein; Epsin-4; Epsin-related protein; EpsinR
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-625
  • 氨基酸序列
    MLNMWKVREL VDKATNVVMN YSEIESKVRE ATNDDPWGPS GQLMGEIAKA TFMYEQFPEL MNMLWSRMLK DNKKNWRRVY KSLLLLAYLI RNGSERVVTS AREHIYDLRS LENYHFVDEH GKDQGINIRQ KVKELVEFAQ DDDRLREERK KAKKNKDKYV GVSSDSVGGF RYSERYDPEP KSKWDEEWDK NKSAFPFSDK LGELSDKIGS TIDDTISKFR RKDREDSPER CSDSDEEKKA RRGRSPKGEF KDEEETVTTK HIHITQATET TTTRHKRTAN PSKTIDLGAA AHYTGDKASP DQNASTHTPQ SSVKTSVPSS KSSGDLVDLF DGTSQSTGGS ADLFGGFADF GSAAASGSFP SQVTATSGNG DFGDWSAFNQ APSGPVASSG EFFGSASQPA VELVSGSQSA LGPPPAASNS SDLFDLMGSS QATMTSSQSM NFSMMSTNTV GLGLPMSRSQ NTDMVQKSVS KTLPSTWSDP SVNISLDNLL PGMQPSKPQQ PSLNTMIQQQ NMQQPMNVMT QSFGAVNLSS PSNMLPVRPQ TNALIGGPMP MSMPNVMTGT MGMAPLGNTP MMNQSMMGMN MNIGMSAAGM GLTGTMGMGM PNIAMTSGTV QPKQDAFANF ANFSK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.
  • 基因功能參考文獻：
    1. Although epsinR has been shown to be a cargo adaptor, the present study indicates that it is an order of magnitude more abundant in CCVs than its known cargo protein, vti1b, suggesting that it may have other functions as well. PMID: 26179914
    2. These results do not support a significant role of GRIA1 or CLINT1 in the development of schizophrenia in the German population. PMID: 21116212
    3. a novel clathrin-associated protein identified through subcellular proteomics; data suggest a role in clathrin-mediated budding on internal membranes PMID: 12213833
    4. might participate in the formation of clathrin-coated vesicles at the level of the trans-Golgi network and remains associated with the vesicles longer than clathrin and adaptors PMID: 12429846
    5. EpsinR is an ENTH domain-containing protein that interacts with AP-1 PMID: 12589059
    6. Our work reveals the existence of clathrin-independent and -dependent transport steps in the retrograde route, and establishes a function for clathrin and epsinR at the endosome-TGN interface. PMID: 15068792
    7. epsinR is an adaptor for vesicle-associated soluble NSF attachment protein receptor PMID: 15371541
    8. Four adjacent markers at the 5' end of the Epsin 4 gene showed significant evidence of linkage disequilibrium with schizophrenia. PMID: 15793701
    9. Results indicate the presence of a locus near the 5' end of Epsin 4 conferring susceptibility to the disease and provide further support for Epsin 4 as an important potential contributor to genetic risk in schizophrenia. PMID: 16402136
    10. characterization of the molecular details governing the sorting of a SNARE into clathrin-coated vesicles, namely the direct recognition of the three-helical bundle H(abc) domain of the mouse SNARE Vti1b by the human clathrin adaptor epsinR PMID: 18033301
    11. Our results suggest that the examined region of Epsin 4 does not have a major influence on susceptibility to schizophrenia in Japanese. PMID: 18696005
    12. Variation in the Epsin 4 gene is significantly associated with psychotic disorder in this Latino population PMID: 18929466

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
  • 蛋白家族：
    Epsin family
  • 組織特異性：
    Ubiquitously expressed at low to intermediate levels.
  • 數據庫鏈接：

    HGNC: 23186

    OMIM: 607265

    KEGG: hsa:9685

    STRING: 9606.ENSP00000429824

    UniGene: Hs.644000



主站蜘蛛池模板： 秋霞在线观看片无码免费不卡| 国产成人午夜福利在线观看| 日本高清www午色夜在线视频| 天堂网在线www资源| 色一情一乱一乱一区99av白浆| 亚洲 欧美 偷自乱 图片| 欧美孕妇变态重口另类| 欧美va免费高清在线观看| 成 人 网 站不卡在线观看| 欧美真人性做爰一二区| 国产成人无码www免费视频播放| 精品性高朝久久久久久久| 久久久久久久波多野结衣高潮| 亚洲自偷自拍另类小说| 国产午夜福利片在线观看| 国产互换人妻hd| 国产99视频精品免费视频76| 妲己丰满人熟妇大尺度人体艺| 国内a∨免费播放| 精品爆乳一区二区三区无码av| 伊人无码精品久久一区二区| 国产精品亚洲一区二区z| 国产一性一交一伦一a片| 欧美人与禽猛交狂配| 狠狠狠色丁香综合婷婷久久| 国产乱女乱子视频在线播放| 艳z门照片无码av| 免费观看女人高潮视频软件| 男女一边摸一边做爽爽的免费阅读| 久久精品国产69国产精品亚洲| 天堂中文在线资源| 337p日本大胆欧久久| 中国精学生妹品射精久久| av在线播放无码线| 久久久久99精品成人片牛牛影视 | 网友自拍区视频精品| 18勿入网站免费永久| 性做久久久久久久| 成年无码av片在线| 国产精品美脚玉足脚交| 国产免费午夜a无码v视频|