在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Citrate synthase, mitochondrial (CS)

Recombinant Human Citrate synthase, mitochondrial (CS)

  • 中文名稱：
    Recombinant Human Citrate synthase, mitochondrial(CS)
  • 貨號：
    CSB-YP006031HU(A4)
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Citrate synthase, mitochondrial(CS)
  • 貨號：
    CSB-EP006031HU(A4)-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Citrate synthase, mitochondrial(CS)
  • 貨號：
    CSB-BP006031HU(A4)
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Citrate synthase, mitochondrial(CS)
  • 貨號：
    CSB-MP006031HU(A4)
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    CISY_HUMAN; Citrate synthase; Citrate synthase; mitochondrial; citrate synthetase; Cs; EC 2.3.3; EC 2.3.3.1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    28-466
  • 氨基酸序列
    ASS TNLKDILADL IPKEQARIKT FRQQHGKTVV GQITVDMMYG GMRGMKGLVY ETSVLDPDEG IRFRGFSIPE CQKLLPKAKG GEEPLPEGLF WLLVTGHIPT EEQVSWLSKE WAKRAALPSH VVTMLDNFPT NLHPMSQLSA AVTALNSESN FARAYAQGIS RTKYWELIYE DSMDLIAKLP CVAAKIYRNL YREGSGIGAI DSNLDWSHNF TNMLGYTDHQ FTELTRLYLT IHSDHEGGNV SAHTSHLVGS ALSDPYLSFA AAMNGLAGPL HGLANQEVLV WLTQLQKEVG KDVSDEKLRD YIWNTLNSGR VVPGYGHAVL RKTDPRYTCQ REFALKHLPN DPMFKLVAQL YKIVPNVLLE QGKAKNPWPN VDAHSGVLLQ YYGMTEMNYY TVLFGVSRAL GVLAQLIWSR ALGFPLERPK SMSTEGLMKF VDSKSG
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. citrate synthase and ACSS1 have tumorigenic functions in hepatocellular carcinoma PMID: 27363021
    2. Citrate synthase activity was lower in patients with heart failure with preserved ejection fraction compared to controls. PMID: 27179829
    3. mir-122 and its targets G6PC3, ALDOA and CS play roles in the hypoxia responses that regulate glucose and energy metabolism and can serve as hypoxia biomarkers. PMID: 27793029
    4. METTL12 methylates CS on Lys-395, which is localized in the CS active site. Interestingly, the METTL12-mediated methylation inhibited CS activity and was blocked by the CS substrate oxaloacetate. PMID: 28887308
    5. Data suggest that METTL12, localized in mitochondrial matrix, modifies/methylates Lys368 of citrate synthase in external surface region close to its catalytic site; addition/removal of methylation has no effect on citrate synthase activity; Lys368 occurs in highly conserved sequence of amino acid residues of citrate synthase. (METTL12 = methyltransferase-like protein 12) PMID: 28391595
    6. Data suggest that downregulation of citrate synthase (CS) expression in 293T cells leads to low level of ATP production, excessive superoxide formation and cell apoptosis, which implies a possible mechanism for hearing loss in A/J mice. PMID: 28216161
    7. Hence, we conclude that SIRT3 exhibits neuroprotection via deacetylating and increasing mitochondrial enzyme activities. PMID: 28161643
    8. Paretic muscle in hemiparetic stroke survivors had lower CS concentration. PMID: 26361074
    9. The citrate synthase knockdown cells exhibited severe defects in respiratory activity and marked decreases in ATP production, but great increases in glycolytic metabolism. PMID: 23139858
    10. Citrate synthase (CS) is a direct RORalpha target gene and one mechanism by which RORalpha regulates lipid metabolism is via regulation of CS expression. PMID: 22485150
    11. Responses of skeletal and cardiac muscles in CS activity and gene expression at 1 and 48 h after endurance training. Acute effect of exercise on training-induced elevation in CS activity in rat soleus but not ventricle muscles. PMID: 12531911
    12. possible role of CS-specific autoantibodies in the pathomechanism of allograft vasculopathy PMID: 15711981
    13. It is likely that enhanced citrate synthase activity contributes to the conversion of glucose to lipids in pancreatic cancer providing substrate for membrane lipids synthesis. PMID: 15714131
    14. These results provide an important basis for the study of mitochondrial dysfunction due to aberrant CSa trafficking. PMID: 19479947

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Citrate synthase family
  • 數據庫鏈接：

    HGNC: 2422

    OMIM: 118950

    KEGG: hsa:1431

    STRING: 9606.ENSP00000342056

    UniGene: Hs.743252



主站蜘蛛池模板： 国产午夜手机精彩视频| 亚洲午夜成人精品无码| 18禁无遮挡啪啪无码网站| 92精品成人国产在线观看| 国产亚洲精品福利视频| 夜夜香夜夜摸夜夜添视频| 美女无遮挡免费视频网站| 久久精品国产最新地址 | 欧美日韩在线第一页免费观看 | 久草热8精品视频在线观看| 人摸人人人澡人人超碰97| 亚洲女人被黑人巨大进入| 男阳茎进女阳道视频大全| 亚洲午夜无码极品久久| 亚洲成a人片在线观看的电影| 男女性高爱潮免费网站| 欧美老肥妇做爰bbww| 四虎国产精品永久入口| 亚洲精品乱码一区二区三区| 欧洲精品一线二线三线区别 | 日本老妇人乱xxy| 国产精品内射视频免费| 800av凹凸视频在线观看| 国产精品a无线| 在线观看国产成人av天堂| 免费人成再在线观看视频| 国产精品久久欧美久久一区| 欧美大屁股xxxxhd黑色| 无套内谢少妇毛片aaaa片免费| 一中文字幕日产乱码va| 成在线人永久免费视频播放| 亚洲一区激情校园小说| 欧美自拍亚洲综合丝袜| 樱桃视频影视在线观看免费| av午夜久久蜜桃传媒软件| 四虎影视无码永久免费| 亚洲狠亚洲狠亚洲狠狠狠 | 欧洲美女与动zooz| 色欲av久久综合人妻无码| 国产大片黄在线观看私人影院| 久久精品中文字幕一区二区三区|