在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cingulin (CGN), partial

  • 中文名稱:
    Recombinant Human Cingulin(CGN) ,partial
  • 貨號:
    CSB-YP005302HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Cingulin(CGN) ,partial
  • 貨號:
    CSB-EP005302HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Cingulin(CGN) ,partial
  • 貨號:
    CSB-EP005302HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Cingulin(CGN) ,partial
  • 貨號:
    CSB-BP005302HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Cingulin(CGN) ,partial
  • 貨號:
    CSB-MP005302HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CGN
  • Uniprot No.:
  • 別名:
    6330408J11Rik; AI647528; AI987749; cgn; CING_HUMAN; Cingulin; DKFZp779N1112; FLJ39281; KIAA1319; MGC118157
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
  • 基因功能參考文獻:
    1. Down-regulation of Cingulin Augments Thrombin-induced Endothelial Barrier Disruption. PMID: 27590342
    2. Cingulin modulates barrier function in endothelium. PMID: 26821949
    3. MgcRacGAP colocalizes with CGN and CGNL1 at TJs and forms a complex and interacts directly in vitro with CGN and CGNL1. PMID: 24807907
    4. Co-imunoprecipitation and confocal microscopy experiments also revealed the tight junction protein cingulin as a new interacting partner of Ubn-1 PMID: 22245583
    5. Results indicate that cells underwent EMT exhibited overactive TGFbeta signaling and loss of expression of the CDH1, CGN, CLDN4, and KLK10 genes as a result of hypermethylation of their corresponding promoter regions. PMID: 20086175
    6. Cingulin (KIAA1319 protein) is localized in the cytoplasmic domain of vertebrate epithelial tight junctions, and it interacts with other tight junction proteins such as ZO-1, and with the actomyosin cytoskeleton. PMID: 11042084

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, tight junction.
  • 蛋白家族:
    Cingulin family
  • 組織特異性:
    Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart.
  • 數據庫鏈接:

    HGNC: 17429

    OMIM: 609473

    KEGG: hsa:57530

    STRING: 9606.ENSP00000271636

    UniGene: Hs.591464



主站蜘蛛池模板: 国产精品久久久久av福利动漫| 亚洲欭美日韩颜射在线| 狠狠色噜噜狠狠狠狠7777米奇| 东北女人啪啪对白| 国产 麻豆 日韩 欧美 久久| 女同亚洲一区二区无线码| 久久se精品一区二区三区| 插一插射一射视频| 美女又黄又免费的视频| 国产精品毛片完整版视频| 男女做爰猛烈啪啪吃奶伸舌头下载 | 熟女精品视频一区二区三区| 日韩人妻无码制服丝袜视频| 国产成人亚洲综合网站小说| 日韩人妻无码免费视频一区二区 | 天堂网在线www中文| 亚洲精品中文字幕无码蜜桃| 荡女精品导航| 久久久av男人的天堂| 久久久99无码一区| 欧美精品videossex少妇| 全球av集中精品导航福利| 国产在线观看片a免费观看| 在线观看精品视频网站| 狠狠噜天天噜日日噜| 久久久久国产一区二区| 天堂最新版资源网| 国产精品无码翘臀在线看 | 日本乱子人伦在线视频| 午夜男女无遮挡拍拍视频| 成码无人av片在线电影网站| 亚洲欧美日韩精品久久| 精品无码av无码专区| 久久综合久久自在自线精品自| 好了av第四综合无码久久| 少妇被粗大猛进进出出s小说| 一本一道精品欧美中文字幕| 国产一区二区三区在线电影| 日韩免费无码专区精品观看| 国产成人精品亚洲午夜麻豆| 日本一道综合久久aⅴ久久|