在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Chloride intracellular channel protein 2 (CLIC2), partial

  • 中文名稱:
    Recombinant Human Chloride intracellular channel protein 2(CLIC2) ,partial
  • 貨號:
    CSB-YP005547HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Chloride intracellular channel protein 2(CLIC2) ,partial
  • 貨號:
    CSB-EP005547HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Chloride intracellular channel protein 2(CLIC2) ,partial
  • 貨號:
    CSB-EP005547HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Chloride intracellular channel protein 2(CLIC2) ,partial
  • 貨號:
    CSB-BP005547HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Chloride intracellular channel protein 2(CLIC2) ,partial
  • 貨號:
    CSB-MP005547HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CLIC2
  • Uniprot No.:
  • 別名:
    CLIC2; Chloride intracellular channel protein 2; XAP121
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
  • 基因功能參考文獻:
    1. We have determined the crystal structure of soluble Clic2 from the euryhaline teleost fish Oreochromis mossambicus. Structural comparison of tilapia and human CLIC2 with other CLICs shows that these proteins are highly conserved. PMID: 29198705
    2. a vital role for the CLIC2 protein in maintaining normal cognitive function via its interaction with RyRs in the brain. PMID: 22814392
    3. CLIC2 inhibited cardiac ryanodine receptor Ca2+ release channels in lipid bilayers when added to the cytoplasmic side of the channels and inhibited Ca2+ release from cardiac sarcoplasmic reticulum vesicles PMID: 15147738
    4. CLIC2 forms pH-dependent chloride channels in vitro with higher channel activity at low pH levels and that the channels are subject to redox regulation PMID: 17945253
    5. Human CLIC2 was crystallized in 2 different forms, in presence of GSSH. Form A displayed P2(1)2(1)2(1) symmetry, with unit-cell parameters a=44.0, b=74.7, c=79.8 A. Form B displayed P2(1) symmetry, with unit-cell parameters a=36.0, b=66.9, c=44.1 A. PMID: 18007051
    6. crystal structure of soluble human CICL2 and implications for function PMID: 18186468

    顯示更多

    收起更多

  • 相關疾病:
    Mental retardation, X-linked, syndromic, 32 (MRXS32)
  • 亞細胞定位:
    Cytoplasm. Membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
  • 蛋白家族:
    Chloride channel CLIC family
  • 組織特異性:
    Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney.
  • 數據庫鏈接:

    HGNC: 2063

    OMIM: 300138

    KEGG: hsa:1193

    STRING: 9606.ENSP00000358460

    UniGene: Hs.655445



主站蜘蛛池模板: 国产 国语对白 露脸| 啪啪后入内射日韩| 第一亚洲中文久久精品无码| 又嫩又硬又黄又爽的视频| 国产农村熟妇videos| 青草视频在线观看视频| 久久综合色_综合色88| 久久精品第九区免费观看| 久久亚洲精精品中文字幕| 国产精品亚洲成在人线| 日本久久久久久久久久加勒比| 加勒比东京热无码一区| 小sao货水好多真紧h视频| 日韩理论午夜无码| 亚洲制服丝袜自拍中文字幕| 狠狠综合久久综合88亚洲| 久久久久人妻精品一区蜜桃| 亚洲欧美日韩愉拍自拍美利坚 | 免费观看又污又黄在线观看| 青青草免费国产线观720| 亚洲熟妇中文字幕五十中出| 精品人妻系列无码人妻不卡| 国产在线高清亚洲精品二区| 成人奭片免费观看| 18禁美女裸体免费网站| 国产亚洲精品ae86| 国产男生夜间福利免费网站| 日韩精品一区二区三区| 亚洲精品久久国产高清情趣图文| 亚洲国产精品无码7777一线| 一本无码人妻在中文字幕| 无码精品视频一区二区三区| 337p人体 欧洲人体 亚洲| 蜜柚av久久久久久久| 中国孕妇变态孕交xxxx| 国产亚洲日韩在线播放更多| 久久人人97超碰a片精品| 午夜天堂一区人妻| 国产成人精品高清在线观看99| 色先锋影音岛国av资源| 99久久99久久精品免费观看|