在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Centromere/kinetochore protein zw10 homolog (ZW10)

Recombinant Human Centromere/kinetochore protein zw10 homolog (ZW10)

  • 中文名稱：
    人ZW10重組蛋白
  • 貨號：
    CSB-YP027154HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人ZW10重組蛋白
  • 貨號：
    CSB-EP027154HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人ZW10重組蛋白
  • 貨號：
    CSB-EP027154HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人ZW10重組蛋白
  • 貨號：
    CSB-BP027154HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人ZW10重組蛋白
  • 貨號：
    CSB-MP027154HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ZW10
  • Uniprot No.：
  • 別名：
    Centromere/kinetochore protein zw10; Centromere/kinetochore protein zw10 homolog; HZW 10; HZW10; Kinetochore associated homolog; KNTC1AP; MGC149821; Zeste white 10; Zeste white 10 homolog; ZW 10; ZW 10 homolog centromere/kinetochore protein; ZW 10 kinetochore associated homolog; ZW10 (Drosophila) homolog centromere/kinetochore protein; Zw10; ZW10 homolog centromere/kinetochore protein (Drosophila); ZW10 homolog centromere/kinetochore protein; ZW10 kinetochore associated homolog; ZW10, kinetochore associated, homolog (Drosophila); ZW10_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-779
  • 氨基酸序列
    ASFVTEVLA HSGRLEKEDL GTRISRLTRR VEEIKGEVCN MISKKYSEFL PSMQSAQGLI TQVDKLSEDI DLLKSRIESE VRRDLHVSTG EFTDLKQQLE RDSVVLSLLK QLQEFSTAIE EYNCALTEKK YVTGAQRLEE AQKCLKLLKS RKCFDLKILK SLSMELTIQK QNILYHLGEE WQKLIVWKFP PSKDTSSLES YLQTELHLYT EQSHKEEKTP MPPISSVLLA FSVLGELHSK LKSFGQMLLK YILRPLASCP SLHAVIESQP NIVIIRFESI MTNLEYPSPS EVFTKIRLVL EVLQKQLLDL PLDTDLENEK TSTVPLAEML GDMIWEDLSE CLIKNCLVYS IPTNSSKLQQ YEEIIQSTEE FENALKEMRF LKGDTTDLLK YARNINSHFA NKKCQDVIVA ARNLMTSEIH NTVKIIPDSK INVPELPTPD EDNKLEVQKV SNTQYHEVMN LEPENTLDQH SFSLPTCRIS ESVKKLMELA YQTLLEATTS SDQCAVQLFY SVRNIFHLFH DVVPTYHKEN LQKLPQLAAI HHNNCMYIAH HLLTLGHQFR LRLAPILCDG TATFVDLVPG FRRLGTECFL AQMRAQKGEL LERLSSARNF SNMDDEENYS AASKAVRQVL HQLKRLGIVW QDVLPVNIYC KAMGTLLNTA ISEVIGKITA LEDISTEDGD RLYSLCKTVM DEGPQVFAPL SEESKNKKYQ EEVPVYVPKW MPFKELMMML QASLQEIGDR WADGKGPLAA AFSSSEVKAL IRALFQNTER RAAALAKIK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER.
  • 基因功能參考文獻：
    1. The RZZ complex was purified to homogeneity and subjected to systemic crystallization. PMID: 25849506
    2. hZwint-1 bridges the inner and outer kinetochore: identification of the kinetochore localization domain and the hZw10-interaction domain PMID: 21345172
    3. Overexpression, microinjection and knockdown experiments revealed that ZW10 is involved in membrane trafficking between the endoplasmic reticulum and Golgi PMID: 15029241
    4. show that ZW10 interacting protein-1(Zwint-1) is required and is sufficient for kinetochore localization of Zeste White 10 (ZW10) in HeLa cells PMID: 15485811
    5. ZW10 serves as a general regulator of dynein function throughout the cell cycle. PMID: 16505164
    6. RINT-1 coordinates the localization and function of ZW10 by serving as a link between ZW10 and the SNARE complex comprising syntaxin 18. PMID: 16571679
    7. targeting of ZW10 to the perinuclear Golgi region was found to depend on the perinuclear accumulation of dynactin PMID: 17560939
    8. RNAi-mediated depletion of ZW10 markedly-reduced congression efficiency. PMID: 17680027
    9. Rab6 regulates distinct Golgi trafficking pathways involving two separate protein complexes: ZW10/RINT-1 and COG. PMID: 17699596
    10. Accumulation of ZW10 at tensionless kinetochores stems from a 4-fold reduction of kinetochore turnover rate and requires aurora B kinase activity. PMID: 18065224
    11. Stable hZW10 kinetochore residency at prometaphase kinetochores is dependent on its interaction with hZwint-1, and is essential for mitotic checkpoint arrest. PMID: 18268100
    12. The interaction between ZW10 and dynamitin showed that the N-terminal region of ZW10 is the major binding site for dynamitin and, like full-length ZW10, could move along microtubules to the centrosomal area in a dynein-dynactin-dependent manner. PMID: 18782227
    13. Results together suggest that NAG links between p31 and ZW10-RINT-1 and is involved in Golgi-to-ER transport. PMID: 19369418

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Lipid droplet.
  • 蛋白家族：
    ZW10 family
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 13194

    OMIM: 603954

    KEGG: hsa:9183

    STRING: 9606.ENSP00000200135

    UniGene: Hs.503886



主站蜘蛛池模板： 伊人成年网站综合网| 亚洲中文字幕无码久久2017| 婷婷综合另类小说色区| 青草视频在线观看视频| 熟妇丰满大屁股在线播放| 国内精品久久久久久久影院| 2021国产精品成人免费视频| 男女无遮挡激情视频| 免费三级现频在线观看免费| 七七久久成人影院网站| 97久久超碰精品视觉盛宴| 加勒比东京热无码一区| 超清av在线播放不卡无码 | 国产欧美成人一区二区a片| 国产av熟女一区二区三区| 国产高清视频一区三区| 精品麻豆丝袜高跟鞋av| 久久www成人免费直播| 东京热无码av男人的天堂| 亚洲永久网址在线观看| 97久久超碰国产精品最新| 男女做爰无遮挡性视频| 欧美影院成年免费版| 欧美成人精品手机在线| 国产福利姬喷水福利在线观看| 国产成人精品免费视频大全软件| 人妻va精品va欧美va| 国产综合精品一区二区三区 | 国产成人无码a区在线观看视频app| 豆国产95在线 | 亚洲| 色综合欧美在线视频区| 四库影院永久国产精品| 国产v亚洲v天堂a无码99| 女厕厕露p撒尿八个少妇| 午夜成人理论福利片| 人妻巨大乳挤奶水hd免费看| 国产美女精品视频线播放| 上司的丰满人妻中文字幕| 久久久成人精品av四区| 婷婷四虎东京热无码群交双飞视频 | 鲁大师在线视频播放免费观看 |