在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Cell division cycle-associated protein 7 (CDCA7)

Recombinant Human Cell division cycle-associated protein 7 (CDCA7)

  • 中文名稱：
    Recombinant Human Cell division cycle-associated protein 7(CDCA7)
  • 貨號：
    CSB-YP874825HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Cell division cycle-associated protein 7(CDCA7)
  • 貨號：
    CSB-EP874825HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Cell division cycle-associated protein 7(CDCA7)
  • 貨號：
    CSB-EP874825HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Cell division cycle-associated protein 7(CDCA7)
  • 貨號：
    CSB-BP874825HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Cell division cycle-associated protein 7(CDCA7)
  • 貨號：
    CSB-MP874825HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CDCA7
  • Uniprot No.：
  • 別名：
    CDCA7; JPO1Cell division cycle-associated protein 7; Protein JPO1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-371
  • 氨基酸序列
    MDARRVPQKD LRVKKNLKKF RYVKLISMET SSSSDDSCDS FASDNFANTR LQSVREGCRT RSQCRHSGPL RVAMKFPARS TRGATNKKAE SRQPSENSVT DSNSDSEDES GMNFLEKRAL NIKQNKAMLA KLMSELESFP GSFRGRHPLP GSDSQSRRPR RRTFPGVASR RNPERRARPL TRSRSRILGS LDALPMEEEE EEDKYMLVRK RKTVDGYMNE DDLPRSRRSR SSVTLPHIIR PVEEITEEEL ENVCSNSREK IYNRSLGSTC HQCRQKTIDT KTNCRNPDCW GVRGQFCGPC LRNRYGEEVR DALLDPNWHC PPCRGICNCS FCRQRDGRCA TGVLVYLAKY HGFGNVHAYL KSLKQEFEMQ A
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.
  • 基因功能參考文獻：
    1. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex; immunodeficiency-centromeric instability-facial anomalies syndrome has a defective HELLS and CDCA7 bipartite nucleosome remodeling complex PMID: 29339483
    2. Transcriptome analysis identified Cdca7 as the top down-regulated gene in Zbtb24 homozygous mutant mESCs, which can be restored by ectopic ZBTB24 expression. Finally, we show that this regulation is conserved between species and that CDCA7 levels are reduced in patients carrying ZBTB24 nonsense mutations PMID: 27466202
    3. Missense mutations in CDCA7 cause immunodeficiency-centromeric instability-facial anomalies syndrome type 3. PMID: 26216346
    4. Data indicate that cell division cycle associated 7 protein (Cdca7) is strongly up-regulated in the hemogenic population during embryonic stem cell hematopoietic differentiation in a Notch-dependent manner. PMID: 25385755
    5. The CDCA7 transcription factor regulates cell proliferation. PMID: 24029427
    6. CDCA7 associates with MYC and this association is modulated in a phosphorylation-dependent manner. PMID: 23166294
    7. JPO1/CDCA7 is a unique transcription regulator whose expression is activated by E2F1 as well as c-Myc. PMID: 16580749

    顯示更多

    收起更多

  • 相關疾病：
    Immunodeficiency-centromeric instability-facial anomalies syndrome 3 (ICF3)
  • 亞細胞定位：
    Nucleus. Cytoplasm. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163.
  • 組織特異性：
    Ubiquitous with higher level in thymus and small intestine. Overexpressed in a large number of tumors, in blood from patients with acute myelogenous leukemia (AML) and in chronic myelogenous leukemia (CML) blast crisis.
  • 數據庫鏈接：

    HGNC: 14628

    OMIM: 609937

    KEGG: hsa:83879

    STRING: 9606.ENSP00000306968

    UniGene: Hs.470654



主站蜘蛛池模板： 久久不见久久见免费影院www日本| 麻豆传传媒久久久爱| 永久免费的av在线电影网无码 | 男女下面进入的视频| 亚洲国产午夜精品理论片妓女| 午夜亚洲国产理论片中文| 国产三级精品三级| 午夜寂寞少妇aaa片毛片| 2021久久精品国产99国产精品| 艳妇乳肉豪妇荡乳在线观看| 风流少妇又紧又爽又丰满| 巨胸美乳无码人妻视频| 亚洲熟少妇在线播放999| 日韩成人av无码一区二区三区| 免费国产午夜视频在线观看| 日韩成人大屁股内射喷水| 亚洲精品乱码久久久久久日本 | 非洲黑人最猛性xxxx交| 欧美日韩免费专区在线| 日韩国产成人无码av毛片蜜柚 | 明星性猛交ⅹxxx乱大交| 日本在线高清不卡免费播放| 国产精品人妻系列21p| 亚洲五月色丁香婷婷婷| 国产熟妇按摩3p高潮大叫| 国产精品一国产精品| 亚洲欧美v国产蜜芽tv| 欧美专区另类专区在线视频| 国产乱子伦精品无码专区| 亚洲综合精品伊人久久| 欧洲精品va无码一区二区三区| 久久99精品国产麻豆婷婷洗澡 | 刺激性视频黄页| 日韩欧美亚洲综合久久影院d3| 欧美性受xxxxzooz乱毛| 中文字幕网伦射乱中文| 国产一区二区野外| 国产精品久久久久电影网| 亚洲国产精品嫩草影院| 最新69国产成人精品视频免费| 亚洲中文字慕日产2021|