在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Cbp/p300-interacting transactivator 4 (CITED4)

Recombinant Human Cbp/p300-interacting transactivator 4 (CITED4)

  • 中文名稱：
    Recombinant Human Cbp/p300-interacting transactivator 4(CITED4)
  • 貨號：
    CSB-YP842752HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Cbp/p300-interacting transactivator 4(CITED4)
  • 貨號：
    CSB-EP842752HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Cbp/p300-interacting transactivator 4(CITED4)
  • 貨號：
    CSB-EP842752HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Cbp/p300-interacting transactivator 4(CITED4)
  • 貨號：
    CSB-BP842752HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Cbp/p300-interacting transactivator 4(CITED4)
  • 貨號：
    CSB-MP842752HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CITED4
  • Uniprot No.：
  • 別名：
    AU019445; AW742964; Cbp/p300 interacting transactivator 4; cbp/p300 interacting transactivator; with glu/asp rich carboxy terminal domain; 4; Cbp/p300-interacting transactivator 4; CITE4_HUMAN; Cited4; MRG 2; MRG-2; Mrg2; MSG1 related protein 2; MSG1-related protein 2; Transcriptional co-activator 4
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-184
  • 氨基酸序列
    MADHLMLAEG YRLVQRPPSA AAAHGPHALR TLPPYAGPGL DSGLRPRGAP LGPPPPRQPG ALAYGAFGPP SSFQPFPAVP PPAAGIAHLQ PVATPYPGRA AAPPNAPGGP PGPQPAPSAA APPPPAHALG GMDAELIDEE ALTSLELELG LHRVRELPEL FLGQSEFDCF SDLGSAPPAG SVSC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells.
  • 基因功能參考文獻：
    1. Studies indicate that CCAAT enhancer binding protein beta (C/EBPB)-transcription factor CITED4 (CITED4) signaling is a pathway in cardioprotection mediating benefits of exercise in heart. PMID: 29098625
    2. Upregulation of CITED4 is associated with colorectal cancer. PMID: 26243458
    3. Demethylation and histone modification can potentially reactivate CITED4 gene expression in some breast cancers and lead to changes in tumour behaviour. PMID: 21755341
    4. CITED4 functions as a transactivator when artificially targeted to a promoter element. CITED4 physically interacts with all TFAP2 isoforms in vitro and strongly co-activates all TFAP2 isoforms in Hep3B cells. PMID: 11744733
    5. Results show that breast cancer development is characterized by either nuclear loss or cytoplasmic translocation of CITED4, with consequent loss of hypoxia-inducible factor-1alpha transcriptional antagonist activity. PMID: 15342390
    6. The interaction and functional cooperation between FHL2, CITED4, and CTNNB were studied. PMID: 15572674
    7. CITED4 is epigenetically silenced in the vast majority of oligodendroglial tumours with 1p and 19q deletions. PMID: 17311001
    8. mutational study of CITED4 in 24 glial tumors (22 primary glioblastomas, 1 low-grade astrocytoma & its recurrent secondary glioblastoma) PMID: 18722883

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    CITED family
  • 組織特異性：
    Expressed in most tissues examined with highest levels of expression in heart, liver, skeletal muscle and pancreas. Also expressed in bladder cell line ECV-304 and in various breast cancer cell lines. Also detected in both in situ and invasive breast tumo
  • 數據庫鏈接：

    HGNC: 18696

    OMIM: 606815

    KEGG: hsa:163732

    STRING: 9606.ENSP00000361721

    UniGene: Hs.355820



主站蜘蛛池模板： 综合激情丁香久久狠狠| 性生交片免费无码看人| 亚洲精品国产第一综合99久久| 绝顶高潮合集videos| 美女黄18以下禁止观看| 免费无码午夜福利片| 国语自产拍在线视频中文| 国产乱人伦av在线麻豆a| 国产狂喷潮在线观看中文| 精品午夜福利无人区乱码一区 | aⅴ亚洲 日韩 色 图网站 播放| 亚洲日本va中文字幕久久| 国产艳妇av在线观看果冻传媒| 欧美尺码专线欧洲b1b1| 国产午夜福利精品一区| 亚洲精品v日韩精品| 亚洲精品一区二区久| 色欲aⅴ亚洲情无码av蜜桃| 久欠精品国国产99国产精2021| 成人国产精品一区二区免费看 | 国产卡一卡二无线乱码| 夜夜影院未满十八勿进| 日本乱偷互换人妻中文字幕| 永久免费无码国产| 日韩午夜理论片 中文字幕 | 日本xxx在线观看免费播放| 免费特级黄毛片| 日韩丰满少妇无吗视频激情内射| 天天爱天天做天天做天天吃中文| 色欲av蜜桃一区二区三| 免费人成视频19674不收费| 国产无套内射普通话对白| 国产成人无码av在线影院| 日射精情感性色视频| 国内精品一区二区三区| 久久久久无码国产精品不卡| 2017亚洲天堂最新地址| 国产成人夜色高潮福利影视| 欧美人与动牲交a精品| 国产在线一区二区av视频| 亚洲色欲色欲www成人网|