在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Carboxypeptidase A4 (CPA4)

  • 中文名稱:
    Recombinant Human Carboxypeptidase A4 (CPA4)
  • 貨號:
    CSB-EP005878HU
  • 規格:
    ¥1536
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    CPA4
  • Uniprot No.:
  • 別名:
    Carboxypeptidase A3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    41.4 kDa
  • 表達區域:
    114-421aa
  • 氨基酸序列
    SSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val.
  • 基因功能參考文獻:
    1. Serum CPA4 concentration combined with lymph node involvement may be used as accurate predictors of liver metastasis in colorectal cancer. PMID: 27780921
    2. CPA4 as a negative regulator of adipogenesis that is down-regulated by FGF-1. Expression of CPA4 in subcutaneous adipose tissue correlated negatively with insulin sensitivity. PMID: 28209092
    3. The crystal structure of the human CPA4 carboxypeptidase in complex with SmCI, a peptide protease inhibitor. PMID: 23746805
    4. NvCL form Nerita versicolor is a tight-binding inhibitor that interacts with the active site of the CPA4 in a substrate-like manner. PMID: 22294694
    5. CPA4 gene is imprinted, with preferential expression from the maternal allele in many fetal tissues, but not in fetal brain. PMID: 12552318
    6. CPA4 functions in neuropeptide processing and regulation in the extracellular environment PMID: 20385563
    7. The three-dimensional structure of procarboxypeptidase-A4 (hPCPA4) has been solved and shows the features of related metallocarboxypeptidase zymogens, with a preformed alpha/beta/-hydrolase active-enzyme moiety (hCPA4) and an inhibiting pro-domain (PD). PMID: 16091843
    8. genetic polymorphism is associated with an increased risk of aggressive prostate cancer among younger patients (< 66 years) PMID: 19245716

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Peptidase M14 family
  • 組織特異性:
    Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele.
  • 數據庫鏈接:

    HGNC: 15740

    OMIM: 607635

    KEGG: hsa:51200

    STRING: 9606.ENSP00000222482

    UniGene: Hs.93764



主站蜘蛛池模板: 狠狠色狠狠色综合日日不卡| 无码少妇一区二区三区视频| 99久久免费国产精精品| 女人喷液抽搐高潮视频| 2020每日更新国产精品视频| 亚洲春色av无码专区在线播放| 人妻无码中文专区久久五月婷 | 日本久久夜夜一本婷婷| 日日摸日日碰夜夜爽亚洲| 国产成人精品日本亚洲第一区| 国产精品igao视频网网址| 亚洲熟妇av日韩熟妇在线| av网站免费线看精品| 国产一区二区亚洲精品 | 国产黄大片在线观看| 久久综合丝袜日本网| 伊人色综合久久天天人守人婷| 四虎www永久在线精品| 三上悠亚久久精品| 四虎永久在线精品无码视频| 小宝贝荡货啊用力水湿aⅴ视频| 亚洲人成电影免费观看在线看| 国产成人精品无码免费看| 亚洲国产无线乱码在线观看| 性色a∨精品高清在线观看| a v 在线视频 亚洲免费| 露脸内射熟女--69xx| 亚洲一区二区三区写真| 四虎永久在线高清国产精品| 亚洲色大成网站www永久在线观看| 丰满少妇被猛烈进入试看| 日韩精品成人无码专区免费| 98色婷婷在线| 极品少妇被猛得白浆直喷白浆小说| 亚洲国产一区二区a毛片| 久久国产精品-国产精品| 国产日韩另类综合11页| 亚洲男人的天堂在线aⅴ视频| 亚洲另类无码一区二区三区| 婷婷久久香蕉五月综合| 蜜臀av色欲a片无码一区|