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Recombinant Human CaiB/baiF CoA-transferase family protein C7orf10 (C7orf10)

  • 中文名稱:
    人SUGCT重組蛋白
  • 貨號:
    CSB-YP867183HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SUGCT重組蛋白
  • 貨號:
    CSB-EP867183HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SUGCT重組蛋白
  • 貨號:
    CSB-EP867183HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SUGCT重組蛋白
  • 貨號:
    CSB-BP867183HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SUGCT重組蛋白
  • 貨號:
    CSB-MP867183HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SUGCT
  • Uniprot No.:
  • 別名:
    SUGCT; C7orf10; DERP13; Succinate--hydroxymethylglutarate CoA-transferase; EC 2.8.3.13; Dermal papilla-derived protein 13; SuccinylCoA:glutarate-CoA transferase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    39-445
  • 氨基酸序列
    QS DMNNIKPLEG VKILDLTRVL AGPFATMNLG DLGAEVIKVE RPGAGDDTRT WGPPFVGTES TYYLSVNRNK KSIAVNIKDP KGVKIIKELA AVCDVFVENY VPGKLSAMGL GYEDIDEIAP HIIYCSITGY GQTGPISQRA GYDAVASAVS GLMHITGPEN GDPVRPGVAM TDLATGLYAY GAIMAGLIQK YKTGKGLFID CNLLSSQVAC LSHIAANYLI GQKEAKRWGT AHGSIVPYQA FKTKDGYIVV GAGNNQQFAT VCKILDLPEL IDNSKYKTNH LRVHNRKELI KILSERFEEE LTSKWLYLFE GSGVPYGPIN NMKNVFAEPQ VLHNGLVMEM EHPTVGKISV PGPAVRYSKF KMSEARPPPL LGQHTTHILK EVLRYDDRAI GELLSAGVVD QHETH
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.
  • 基因功能參考文獻:
    1. Chromosome microarray analysis showed a 125kb homozygous pathogenic deletion, which includes genes MPLKIP and SUGCT, not described before. This is the first case described in Peru of a novel contiguous gene deletion of Trichothiodystrophy type 4 and Glutaric aciduria type 3 performed by chromosome microarray analysis. PMID: 29421601
    2. C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, which is the enzyme that converts glutarate to glutaryl-CoA PMID: 23893049
    3. Identified as a candidate disease gene for OXPHOS disorders by next-generation sequencing PMID: 22277967
    4. Geneic mapping of GA3 to chromosome 7 and identification of mutations in c7orf10 are reported. PMID: 18926513
  • 相關疾病:
    Glutaric aciduria 3 (GA3)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    CaiB/BaiF CoA-transferase family
  • 組織特異性:
    Highly expressed in kidney. Intermediate expression in liver, skeletal muscle and pancreas. Little to no expression detected in other tissues examined.
  • 數據庫鏈接:

    HGNC: 16001

    OMIM: 231690

    KEGG: hsa:79783

    UniGene: Hs.586313



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