在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human COMM domain-containing protein 7 (COMMD7)

Recombinant Human COMM domain-containing protein 7 (COMMD7)

  • 中文名稱：
    Recombinant Human COMM domain-containing protein 7(COMMD7)
  • 貨號：
    CSB-YP774817HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human COMM domain-containing protein 7(COMMD7)
  • 貨號：
    CSB-EP774817HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human COMM domain-containing protein 7(COMMD7)
  • 貨號：
    CSB-EP774817HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human COMM domain-containing protein 7(COMMD7)
  • 貨號：
    CSB-BP774817HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human COMM domain-containing protein 7(COMMD7)
  • 貨號：
    CSB-MP774817HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    COMMD7
  • Uniprot No.：
  • 別名：
    C20orf92; Chromosome 20 open reading frame 92; COMD7_HUMAN; COMM domain containing 7; COMM domain containing protein 7; COMM domain-containing protein 7; COMMD 7; COMMD7; dJ1085F17.3; FLJ14987; MGC33315; OTTHUMP00000030609
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-200
  • 氨基酸序列
    MGRLHCTEDP VPEAVGGDMQ QLNQLGAQQF SALTEVLFHF LTEPKEVERF LAQLSEFATT NQISLGSLRS IVKSLLLVPN GALKKSLTAK QVQADFITLG LSEEKATYFS EKWKQNAPTL ARWAIGQTLM INQLIDMEWK FGVTSGSSEL EKVGSIFLQL KLVVKKGNQT ENVYIELTLP QFYSFLHEME RVRTSMECFC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Associates with the NF-kappa-B complex and suppresses its transcriptional activity.
  • 基因功能參考文獻：
    1. COMMD7 activates CXCL10 production by regulating NFkappaB and the production of ROS. The present study highlighted the role of COMMD7 in the development of HCC, and provides novel options for anticancer drug design. PMID: 29532873
    2. COMMD7 up-regulation is correlated with a novel NF-kappaB positive feedback loop in hepatocellular carcinoma, regulation cell proliferation, cell migration and apoptosis. PMID: 27129158
    3. High COMMD7 expression was specifically detected in pancreatic ductal adenocarcinoma tissues and pancreatic ductal adenocarcinoma cell lines. In addition, COMMD7 overexpression positively correlated with histological differentiation and tumor node metastasis (TNM) stage. PMID: 27350032
    4. The present data suggests a potential role of CXCL10 in the oncogenic function of COMMD7. PMID: 28142122
    5. COMMD7's binding to NEMO does not interfere with the binding to the IKKs, and that the disruption of the IKK complex through the use of the NBP competitor impairs the termination of NF-kappaB activity PMID: 26060140
    6. COMMD7 contributes to hepatocellular carcinoma progression by reducing cell apoptosis and overcoming cell cycle arrest. PMID: 23049798
    7. BC047440 can promote the growth and invasion of hepatocellular carcinoma. PMID: 20979692

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasmic vesicle.
  • 組織特異性：
    Widely expressed with highest expression in lung.
  • 數據庫鏈接：

    HGNC: 16223

    OMIM: 616703

    KEGG: hsa:149951

    STRING: 9606.ENSP00000278980

    UniGene: Hs.408427



主站蜘蛛池模板： 巨大欧美黑人xxxxbbbb| 99视频精品全部免费免费观看| 国色天香国产精品| 2020精品国产户外| 无码一区二区三区av在线播放 | 国产成人人人97超碰超爽8| 国产成人精品免费视频大全五级| 狠狠色狠狠色狠狠五月| 亚洲性无码av在线dvd| 亚洲精品天堂成人片av在线播放| 国产v亚洲v天堂无码久久久| 国内熟妇人妻色在线视频| 婷婷色五月开心五月| 在线精品视频一区二区三区| 国产最新进精品视频| 午夜成人爽爽爽视频在线观看| 国产精品人成电影在线观看| 人与性动交aaaabbbb| 国产熟妇搡bbbb搡bbbb| 精品国产一区二区三区色欲| 日本成本人三级在线观看| 免费无码又爽又刺激高潮的app| 又粗又硬又大又爽免费视频播放| 蜜臀av午夜一区二区三区| 国产成 人 综合 亚洲专区| 蜜臀av 国内精品久久久| 99久久久精品免费观看国产| 国色天香成人网| 欧美激情猛片xxxⅹ大3| 在线视频国产制服丝袜| 18禁成人网站免费观看| 国产精品色无码av在线观看| 免费看撕开奶罩揉吮奶头视频| 久久99精品久久久久久9蜜桃| 久久久www成人免费无遮挡大片| 国产精品久久久久久久妇| 日韩视频无码免费一区=区三区| 少妇一晚三次一区二区三区| 女人被狂躁c到高潮视频| 蜜乳av久久久久久久久久久| 亚洲第一无码av无码专区|