在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human CHRNA7-FAM7A fusion protein (CHRFAM7A), partial

Recombinant Human CHRNA7-FAM7A fusion protein (CHRFAM7A), partial

  • 中文名稱：
    Recombinant Human CHRNA7-FAM7A fusion protein(CHRFAM7A),partial
  • 貨號：
    CSB-YP670962HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human CHRNA7-FAM7A fusion protein(CHRFAM7A),partial
  • 貨號：
    CSB-EP670962HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human CHRNA7-FAM7A fusion protein(CHRFAM7A),partial
  • 貨號：
    CSB-EP670962HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human CHRNA7-FAM7A fusion protein(CHRFAM7A),partial
  • 貨號：
    CSB-BP670962HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human CHRNA7-FAM7A fusion protein(CHRFAM7A),partial
  • 貨號：
    CSB-MP670962HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CHRFAM7A
  • Uniprot No.：
  • 別名：
    CHRFAM7A; CHRNA7-FAM7A fusion protein; CHRNA7-DR1; D-10
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. gp120IIIB promotes the downregulation of CHRFAM7A in neuronal cells. PMID: 26567012
    2. Data show preferential fetal CHRFAM7A expression in the human prefrontal cortex and suggest abnormalities in the CHRFAM7A/CHRNA7 ratios in schizophrenia and bipolar disorder, due mainly to overexpression of CHRFAM7A. PMID: 26206074
    3. Data show that a 1 kb sequence in the untranslated regions of the alpha7-nicotinic acetylcholine receptor (alpha7nAChR) gene CHRFAM7A that is modulated by lipopolysaccharides (LPS). PMID: 25681457
    4. This association study was replicated in the NIA-LOAD Familial Study dataset. CHRFAM7A is a dominant negative regulator of CHRNA7 function, the receptor that facilitates amyloid-beta1-42 internalization through endocytosis and has been implicated in AD. PMID: 24787912
    5. CHRFAM7A, a human-specific and partially duplicated alpha7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injury. PMID: 25473097
    6. the involvement of CHRFAM7A in the pathophysiology of the idiopathic generalized epilepsy and indication that c.497-498TG deletion or a nearby polymorphism in the CHRFAM7A gene may play a role in the pathogenesis of this disease PMID: 24024466
    7. lack of CHRFAM7A expression in ADNFLE patients might be an important factor in the pathogenesis of autosomal dominant nocturnal frontal lobe epilepsy PMID: 23553139
    8. evidence on the association between variations in CHRNA7 or CHRFAM7A and the risk of dementia is still sparse and inconclusive. Further studies are needed to establish whether some polymorphisms may affect the probability of developing dementia [review] PMID: 22300029
    9. the partially duplicated alpha7 nAChR subunit gene may specifically participate in the inflammatory response of the innate immune system. PMID: 20926142
    10. 3-Mb map of 15q13-q14 showing that CHRFAM7A is part of a large segmental duplication in the opposite orientation to CHRNA7 and revealing several other duplications PMID: 11829490
    11. Human mesothelioma cells and human biopsies of mesothelioma as well as of normal pleural mesothelial cells functionally express CHRNA7. PMID: 14729617
    12. Results demonstrate that human and rat nicotinic acetylcholine receptors are senstive targets for volatile organic compounds in industrial products and are used in the risk assessment of these compounds. PMID: 15885267
    13. CHRFAM7A was identified as a candidate gene in the D15S165 region in a study of allelic variants at chromosome 15q14 in schizophrenia. PMID: 16417613
    14. These observations indicate that episodic memory function is a schizophrenia endophenotype and implicate the CHRFAM7A/CHRNA7 locus in modulating its function. PMID: 17012698
    15. In persons with bipolar type schizoaffective disorder, CHRNA7 promoter region allelic variants are linked to the capacity to inhibit the P50 auditory evoked potential and thus are associated with a type of illness similar to schizophrenia. PMID: 17192894
    16. In 20 smoking-matched people (n = 10 schizophrenia, n = 10 controls), we found significantly lower CHRFAM7A in cotinine and self-reported smokers versus nonsmokers (p PMID: 19082523
    17. No significant associations of 2-bp deletion or CHRFAM7A copy number with antisaccade performance parameters were observed. PMID: 19149910
    18. polymorphism of CHRFAM7A can be implicated in Alzheimer's disease, dementia with Lewy bodies and Pick's disease PMID: 19641318

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ligand-gated ion channel (TC 1.A.9) family
  • 組織特異性：
    Expressed in hippocampus.
  • 數據庫鏈接：

    HGNC: 15781

    OMIM: 609756

    KEGG: hsa:89832

    STRING: 9606.ENSP00000299847

    UniGene: Hs.510853



主站蜘蛛池模板： 午夜理论片yy44880影院| 人人澡人人妻人人爽人人蜜桃| 亚洲国产欧洲综合997久久| av无码小缝喷白浆在线观看| 国产精品美脚玉足脚交| 午夜大片男女免费观看爽爽爽尤物| 在线观看老湿视频福利| 九色九九九老阿姨| 日本一区二区a√成人片| 中文字字幕在线精品乱码| 国自产偷精品不卡在线| 亚洲产国偷v产偷v自拍色戒| 欧美乱码伦视频免费| 亚洲精品一卡2卡三卡4卡| 午夜三级a三级三点窝| 乱码午夜-极品国产内射| 色欲天天天综合网| 综合亚洲综合图区网友自拍| 高级会所人妻互换94部分| 人人爽人人模人人人爽人人爱| 日韩精品亚洲色大成网站| 成人乱码一区二区三区av| 一卡二卡三卡视频| 国产在线看片免费人成视频| 国产精品日本亚洲欧美| 天天躁日日躁狠狠躁av麻豆| 成在人线av无码免费看| 精品一区二区三区影院在线午夜| 国产成人无码精品亚洲| 人人妻人人澡人人爽人人精品av| 亚洲欧洲日产国码中文字幕| 国产精品卡一卡2卡3卡4| 精品香蕉一区二区三区| 成人欧美一区在线视频| 国产美女裸身网站免费观看视频| 成熟妇人a片免费看网站| 欧美性生交大片免费看| 久久综合久久自在自线精品自| 野外亲子乱子伦视频丶| 亚洲欧美日韩精品色xxx| 久久香蕉国产线看观看亚洲小说|