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  4. Recombinant Human C2 calcium-dependent domain-containing protein 4A (C2CD4A)

Recombinant Human C2 calcium-dependent domain-containing protein 4A (C2CD4A)

  • 中文名稱：
    Recombinant Human C2 calcium-dependent domain-containing protein 4A(C2CD4A)
  • 貨號：
    CSB-YP818765HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human C2 calcium-dependent domain-containing protein 4A(C2CD4A)
  • 貨號：
    CSB-EP818765HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human C2 calcium-dependent domain-containing protein 4A(C2CD4A)
  • 貨號：
    CSB-EP818765HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human C2 calcium-dependent domain-containing protein 4A(C2CD4A)
  • 貨號：
    CSB-BP818765HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human C2 calcium-dependent domain-containing protein 4A(C2CD4A)
  • 貨號：
    CSB-MP818765HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    C2CD4A
  • Uniprot No.：
  • 別名：
    C2CD4A; FAM148A; NLF1C2 calcium-dependent domain-containing protein 4A; Nuclear-localized factor 1; Protein FAM148A
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-369
  • 氨基酸序列
    MWCLERLRLG PECLRRSGDW LLPGRARGAK SRTTAACANV LTPDRIPEFC IPPRLMPRLA LAALRNSWVE EAGMDEGAGR TDWDPRSQAA LSLPHLPRVR TAYGFCALLE SPHTRRKESL LLGGPPAPRP RAHTYGGGGG PDALLGTLRV PRAPGPATPA APGCPRPPQD ALARRPRGCR LLRVPDGLLS RALRAGRSRR LTRVRSVSSG NEDKERRAGS QSPARAPSTS PPSSRVPFPE RLEAEGTVAL GRAGDALRLA AEYCPGTGRL RLRLLRAESP AGGAPGPRAV SCRLSLVLRP PGTALRQCST VVGRSRKASF DQDFCFDGLS EDEVRRLAVR VKARDEGRGR ERGRLLGQGE LSLGALLLL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in inflammatory process. May regulate cell architecture and adhesion.
  • 基因功能參考文獻：
    1. rs7163757 contributes to genetic risk of islet dysfunction and type 2 diabetes by increasing NFAT-mediated islet enhancer activity and modulating C2CD4B, and possibly C2CD4A, expression in (patho)physiologic states. PMID: 29625024
    2. C2CD4A expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    3. An endoplasmic reticulum protein, NLF-1, delivers a sodium leak channel critical for rhythmic locomotion. PMID: 23522043
    4. Single nucleotide polymorphism in C2CD4A is associated with type 2 diabetes. PMID: 20818381
    5. NLF1 may play a role in regulating genes which control cellular architecture. PMID: 15527968

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    C2CD4 family
  • 組織特異性：
    Specifically expressed in endothelial cells.
  • 數據庫鏈接：

    HGNC: 33627

    OMIM: 610343

    KEGG: hsa:145741

    STRING: 9606.ENSP00000347712

    UniGene: Hs.202656



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