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  4. Recombinant Human Bromodomain-containing protein 1 (BRD1), partial

Recombinant Human Bromodomain-containing protein 1 (BRD1), partial

  • 中文名稱：
    Recombinant Human Bromodomain-containing protein 1(BRD1) ,partial
  • 貨號：
    CSB-YP002799HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Bromodomain-containing protein 1(BRD1) ,partial
  • 貨號：
    CSB-EP002799HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Bromodomain-containing protein 1(BRD1) ,partial
  • 貨號：
    CSB-EP002799HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Bromodomain-containing protein 1(BRD1) ,partial
  • 貨號：
    CSB-BP002799HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Bromodomain-containing protein 1(BRD1) ,partial
  • 貨號：
    CSB-MP002799HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BRD1
  • Uniprot No.：
  • 別名：
    BR140-like protein; BRD1; BRD1_HUMAN; BRL; Bromodomain and PHD finger-containing protein 2; Bromodomain containing 1; Bromodomain-containing protein 1; BRPF1; BRPF2; DKFZp686F0325
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

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靶點詳情

  • 功能：
    Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, that acts as a regulator of hematopoiesis. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby promoting erythroid differentiation.
  • 基因功能參考文獻：
    1. There was no association between SNPs in the BRD1 and ZBED4 genes and schizophrenia in the Chinese population. PMID: 29794561
    2. TIMP-4, NT-proANP, NT-proBNP were strongest associated with PAF and AHRE. The discriminatory performance of CHADS2-VASc for PAF was increased by addition of selected biomarkers. PMID: 28431065
    3. Reduced BRD1 expression is associated with Schizophrenia. PMID: 28095495
    4. Findings show that BRD1 primarily binds in close proximity to transcription start sites and regulates expression of numerous genes, many of which are involved with brain development and susceptibility to mental disorders. PMID: 27142060
    5. The PHD finger of BRPF2 can potentially bind DNA non-specifically with an evolutionarily conserved and positively charged surface. PMID: 22820306
    6. BRD1 may have a role in schizophrenia and bipolar affective disorder PMID: 19693800
    7. The association of BRD1 with schizophrenia in a Japanese population, was analysed. PMID: 19908236
    8. These results suggest a general role of BRD1 in the cell and stress that the two BRD1 variants may play different roles in the etiology of psychiatric disease. PMID: 19763615

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  • 亞細胞定位：
    Nucleus. Chromosome.
  • 組織特異性：
    Highly expressed in testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1102

    OMIM: 604589

    KEGG: hsa:23774

    STRING: 9606.ENSP00000216267

    UniGene: Hs.127950



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