在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3), partial

Recombinant Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3), partial

  • 中文名稱：
    人GCNT3重組蛋白
  • 貨號(hào)：
    CSB-YP009329HU1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GCNT3重組蛋白
  • 貨號(hào)：
    CSB-EP009329HU1
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GCNT3重組蛋白
  • 貨號(hào)：
    CSB-EP009329HU1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GCNT3重組蛋白
  • 貨號(hào)：
    CSB-BP009329HU1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GCNT3重組蛋白
  • 貨號(hào)：
    CSB-MP009329HU1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GCNT3
  • Uniprot No.：
  • 別名：
    GCNT3; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; C2GnT-mucin type; C2GnT-M; hC2GnT-M; Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase; C2/4GnT
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
  • 基因功能參考文獻(xiàn)：
    1. GCNT3 was regarded as an oncogene in non-small cell lung cancer, and a target of miR-302b-3p, which regulated cell proliferation, migration and invasion in a GCNT3-dependent manner and E-cadherin, N-cadherin, vimentin, cyclin D1 and p-Erk appeared to be downstream molecules of the miR-302b-3p/GCNT3 pathway. PMID: 30355927
    2. In this Molecular Pathways article, we briefly discuss the potential role of mucin synthesis in cancers, ways to improve drug delivery and disrupt mucin mesh to overcome chemoresistance by targeting mucin synthesis, and the unique opportunity to target the GCNT3 pathway for the prevention and treatment of cancers. PMID: 28039261
    3. This study provides the concepts toward the design of carbohydrate-dependent inhibition of EPEC and EHEC O157:H7 adhesion to human intestinal epithelial cells. PMID: 25701318
    4. In HeLa cells transiently expressing C2GnT-M-GFP, knockdown of KRT1 does not affect Golgi morphology but leaves C2GnT-M outside of the Golgi, resulting in the formation of sialyl-T antigen. PMID: 25605727
    5. low GCNT3 expression is a promising prognostic biomarker for colon cancer that could be used to identify early-stage colon cancer patients at high risk of relapse. PMID: 25466507
    6. Golgi fragmentation is accompanied by the increased association of NMIIA with C2GnT-M and its degradation by proteasomes. PMID: 23396488
    7. Data show that the Golgi docking of vesicular complexes (VCs) use different golgins for docking: C2GnT-M-carrying VC (C2GnT-M-VC) utilizes Giantin, whereas C1GalT1-VC employs GM130-GRASP65 complex. PMID: 22988244
    8. C2GnT2 KO mice have decreased mucosal barrier function in the digestive tract, reduced levels of circulating IgGs and fecal IgA, and increased susceptibility to experimental colitis PMID: 20816165
    9. EGF suppressed C2GnT activity in a time- and dose-dependent fashion, and also suppressed core 4 beta1,6 N-acetylglucosaminyltransferase (C4GnT) activity PMID: 12600830
    10. Frequently downregulated in colorectal cancer and suppresses colon cancer cell growth. PMID: 16418723
    11. Results describe the identification of the cis-regulatory elements of human C2GnT-M gene. PMID: 17303715

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 14 family
  • 組織特異性：
    Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4205

    OMIM: 606836

    KEGG: hsa:9245

    STRING: 9606.ENSP00000379377

    UniGene: Hs.194710



主站蜘蛛池模板： 国产成人综合久久三区| 中文在线8资源库| 精品无码国产自产拍在线观看蜜| 婷婷四房色播| 亚洲欧美综合中文| 国产清纯美女遭强到高潮| 精品av综合导航| 日本精品少妇一区二区三区 | 亚洲 日韩 欧美 有码 在线| 嫩草国产福利视频一区二区| 女人夜夜春精品a片| 可以看三级的网站| 在线精品视频一区二区| 国产成人av在线影院无毒| 熟妇人妻系列av无码一区二区 | 日本一道本高清一区二区| 久久久97丨国产人妻熟女| 亚洲日韩欧美国产高清αv| 久久先锋男人av资源网站| 国产成+人+综合+亚洲 欧美| 丁香婷婷综合激情五月色| 亚洲精品国偷拍自产在线观看蜜臀| 三级在线看中文字幕完整版| 亚洲精品久久yy5099| 国产大学生粉嫩无套流白浆 | 欧美成人看片黄a免费看| 国产成人 综合 亚洲欧洲| 精品视频在线观自拍自拍| 自拍偷自拍亚洲精品被多人伦好爽 | 四虎永久地址www成人久久| 中文字字幕人妻中文| 一本大道久久东京热无码av| 清纯唯美经典一区二区| 久久无码人妻一区二区三区午夜| 亚洲夜夜性无码| 日本丰满护士bbw| 久久理论片午夜琪琪电影院| 少妇扒开腿让我爽了一夜| 高潮毛片无遮挡高清视频播放| 99久久无色码中文字幕人妻蜜柚| 国产精品天干在线观看|