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  4. Recombinant Human Band 4.1-like protein 1 (EPB41L1), partial

Recombinant Human Band 4.1-like protein 1 (EPB41L1), partial

  • 中文名稱：
    人EPB41L1重組蛋白
  • 貨號：
    CSB-YP867149HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EPB41L1重組蛋白
  • 貨號：
    CSB-EP867149HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EPB41L1重組蛋白
  • 貨號：
    CSB-EP867149HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EPB41L1重組蛋白
  • 貨號：
    CSB-BP867149HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EPB41L1重組蛋白
  • 貨號：
    CSB-MP867149HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    EPB41L1
  • Uniprot No.：
  • 別名：
    4.1N; Band 4.1 like protein 1; Band 4.1-like protein 1; DKFZp686H17242; E41L1_HUMAN; EPB41L 1; Epb41l1; Erythrocyte membrane protein band 4.1 like 1; KIAA0338; MGC11072; MRD11; Neuron type nonerythroid protein 4.1; Neuronal protein 4.1; Nonerythroid protein 4.1; Nonerythroid protein 4.1; neuron type; OTTHUMP00000030825; OTTHUMP00000030826; OTTHUMP00000030827; OTTHUMP00000030829
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.
  • 基因功能參考文獻：
    1. 4.1N, betaII spectrin and ankyrin G are structural components of the lateral membrane skeleton and this skeleton plays an essential role in the assembly of a fully functional lateral membrane. PMID: 29428502
    2. Data suggest that repression of JNK-c-Jun signaling through pancreatic polypeptide receptor 1 (PP1) is one of the key anti-tumor mechanisms of neuronal membrane cytoskeletal protein 4.1 (4.1N). PMID: 26575790
    3. the data of the current study identified 4.1N as an inhibitor of hypoxiainduced tumor progression in epithelial ovarian cancer cells. PMID: 26648170
    4. Kainate receptor GluK2a post-translational modifications differentially regulate association with 4.1N to control activity-dependent receptor endocytosis PMID: 23400781
  • 相關疾病：
    Mental retardation, autosomal dominant 11 (MRD11)
  • 亞細胞定位：
    Cytoplasm, cytoskeleton.
  • 組織特異性：
    Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 3378

    OMIM: 602879

    KEGG: hsa:2036

    STRING: 9606.ENSP00000337168

    UniGene: Hs.437422



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