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Recombinant Human BTB/POZ domain-containing protein 9 (BTBD9)

  • 中文名稱:
    Recombinant Human BTB/POZ domain-containing protein 9(BTBD9)
  • 貨號:
    CSB-YP850413HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human BTB/POZ domain-containing protein 9(BTBD9)
  • 貨號:
    CSB-EP850413HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human BTB/POZ domain-containing protein 9(BTBD9)
  • 貨號:
    CSB-EP850413HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human BTB/POZ domain-containing protein 9(BTBD9)
  • 貨號:
    CSB-BP850413HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human BTB/POZ domain-containing protein 9(BTBD9)
  • 貨號:
    CSB-MP850413HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    BTBD9
  • Uniprot No.:
  • 別名:
    BTB/POZ domain-containing protein 9; Btbd9; BTBD9_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-612
  • 氨基酸序列
    MSNSHPLRPF TAVGEIDHVH ILSEHIGALL IGEEYGDVTF VVEKKRFPAH RVILAARCQY FRALLYGGMR ESQPEAEIPL QDTTAEAFTM LLKYIYTGRA TLTDEKEEVL LDFLSLAHKY GFPELEDSTS EYLCTILNIQ NVCMTFDVAS LYSLPKLTCM CCMFMDRNAQ EVLSSEGFLS LSKTALLNIV LRDSFAAPEK DIFLALLNWC KHNSKENHAE IMQAVRLPLM SLTELLNVVR PSGLLSPDAI LDAIKVRSES RDMDLNYRGM LIPEENIATM KYGAQVVKGE LKSALLDGDT QNYDLDHGFS RHPIDDDCRS GIEIKLGQPS IINHIRILLW DRDSRSYSYF IEVSMDELDW VRVIDHSQYL CRSWQKLYFP ARVCRYIRIV GTHNTVNKIF HIVAFECMFT NKTFTLEKGL IVPMENVATI ADCASVIEGV SRSRNALLNG DTKNYDWDSG YTCHQLGSGA IVVQLAQPYM IGSIRLLLWD CDDRSYSYYV EVSTNQQQWT MVADRTKVSC KSWQSVTFER QPASFIRIVG THNTANEVFH CVHFECPEQQ SSQKEENSEE SGTGDTSLAG QQLDSHALRA PSGSSLPSSP GSNSRSPNRQ HQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. results confirmed the association of BTBD9 and MAP2K5/SKOR1 with primary Restless Legs Syndrome in Chinese population PMID: 28329290
    2. Our findings confirm an association between the BTBD9, MEIS1, and MAP2K5/SKOR1 SNPs and periodic limb movements of sleep in an elderly cohort. PMID: 26498236
    3. The GLO1 variations were not the source of association of the BTBD9 locus with restless legs syndrome. PMID: 26298793
    4. The results of this study BTBD9 suggest that the examined BTBD9 variants are not associated with GTS risk, but may be associated with comorbidity and tic severity in the Polish population. PMID: 24993631
    5. Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD PMID: 25142570
    6. The BTBD9 gene is associated with symptoms of antipsychotic-induced restless legs syndrome in schizophrenia. PMID: 23361623
    7. There was a statistically significant association between the variant rs9296249 of the BTBD9 gene and the TS phenotype PMID: 22914617
    8. A frequent polymorphism in BTBD9 was significantly associated with serum ferritin and low iron stores in blood donors. PMID: 22486183
    9. Variants in MEIS1, BTBD9, and MAP2K5/SKOR1 confer a significant risk of restless legs syndrome in a United States population. PMID: 21925394
    10. This is the first demonstration of a genetic influence on RLS in ESRD patients with BTBD9 being significantly associated. PMID: 21572129
    11. We have discovered a variant associated with susceptibility to periodic limb movements in sleep. PMID: 17634447
    12. BTBD9, was recently linked to restless legs syndrome, periodic limb movements and iron status in humans PMID: 18363860
    13. Among the known loci, BTBD9 seems to be the most consistent in its effect on RLS across populations. PMID: 19279021
    14. BTBD9 that predispose to restless legs syndrome and periodic limb movements during sleep are also associated with Tourette syndrome PMID: 19822783

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  • 相關疾病:
    Restless legs syndrome 6 (RLS6)
  • 組織特異性:
    Detected in the brain (at protein level). Moderately expressed in all specific brain regions examined. Expressed in the dopaminergic neurons of the substantia nigra and A11 neurons. Highly expressed in kidney and moderately expressed in all other adult an
  • 數據庫鏈接:

    HGNC: 21228

    OMIM: 611185

    KEGG: hsa:114781

    STRING: 9606.ENSP00000386121

    UniGene: Hs.603858



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