在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human BEN domain-containing protein 3 (BEND3), partial

  • 中文名稱:
    Recombinant Human BEN domain-containing protein 3(BEND3),partial
  • 貨號:
    CSB-YP729205HU
  • 規格:
    ¥1500
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    BEND3
  • Uniprot No.:
  • 別名:
    BEN domain containing 3; BEN domain-containing protein 3; Bend3; BEND3_HUMAN; KIAA1553; RP11-59I9.2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Yeast
  • 分子量:
    17.5kDa
  • 表達區域:
    328-461aa
  • 氨基酸序列
    CLPQLNDFFSRFWAQREMEDSQPSGQVASFFEAEQVDPGHFLDNKDQEEALSLDRSSTIASDHVVDTQDLTEFLDEASSPGEFAVFLLHRLFPELFDHRKLGEQYSCYGDGGKQELDPQRLQIIRNYTEIYFPD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination. Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites. Stimulates the ERCC6L translocase and ATPase activities.
  • 基因功能參考文獻:
    1. Data shows that BEND3 associates with chromatin remodeling complexes to modulate gene expression and heterochromatin organization. PMID: 26507581
    2. propose that there is a link between binding of BEND3 to the CALR rs138452745 C-allele and removal of NFI binding site from this nucleotide, and the evolution of human-specific higher brain functions PMID: 26481236
    3. Data show that SUMOylated BANP, E5R, and Nac1 (BEN) domain 3 (BEND3) stabilizes NoRC component TTF-1-interacting protein 5 (Tip5)via association with ubiquitin specific protease 21 (USP21) debiquitinase. PMID: 26100909
    4. Three basic amino acid residues located in the N-terminal region of BEND3 (BEND356-58, KRK) are essential for its nuclear localization, suggesting that these residues play a role as a functional nuclear localization signals. PMID: 25600804
    5. associates with heterochromatin and represses transcription PMID: 21914818

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus, nucleolus.
  • 組織特異性:
    Expressed at least in heart, kidney, liver, ovary and spleen, with highest levels in spleen and lowest in heart. Expressed on the surface of T-cells.
  • 數據庫鏈接:

    HGNC: 23040

    OMIM: 616374

    KEGG: hsa:57673

    STRING: 9606.ENSP00000358038

    UniGene: Hs.418045



主站蜘蛛池模板: 日韩精品一区二区三区中文| 国产激情电影综合在线看| 毛片内射-百度| 亚洲天堂男人影院| 国产无遮挡无码视频免费软件| 国产又黄又刺激又高潮的网站 | 一 级做人爱全视频在线看| 国产精品原创巨作av女教师| 色伦专区97中文字幕| 无码喷水一区二区浪潮av| 一区二区三区内射美女毛片| 夜夜未满十八勿进的爽爽影院| 丰满少妇高潮惨叫久久久一| av天堂久久精品影音先锋| 色五月丁香六月欧美综合| 久久久久无码国产精品一区| 欧美96在线 | 欧| 日本熟妇hdsex视频| 久久精品成人亚洲另类欧美 | 五月综合色婷婷在线观看 | 综合图区亚洲欧美另类图片| 亚洲精品乱码久久久久久蜜桃图片| 色综合色欲色综合色综合色综合r| 丰满的少妇xxxxx人| 久久性色av亚洲电影| 特级精品毛片免费观看| 亚洲国产午夜精品理论片| 午夜成人无码片在线观看影院| 亚洲精品无码鲁网午夜| 欧美成人片在线观看| 鲁一鲁一鲁一鲁一澡| 久久久www成人免费看片| 中文字幕精品av乱码在线| 失禁大喷潮在线播放| 欧美xxxx做受欧美1314| 国产成人精品视频国产| 国产成人精品一区二区三区无码 | 18禁黄无遮挡网站免费| 久久久久影院美女国产主播| 少妇大叫好爽受不了午夜视频| 亚洲精品字幕在线观看|