在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human B-cell CLL/lymphoma 9-like protein (BCL9L), partial

Recombinant Human B-cell CLL/lymphoma 9-like protein (BCL9L), partial

  • 中文名稱：
    Recombinant Human B-cell CLL/lymphoma 9-like protein(BCL9L) ,partial
  • 貨號：
    CSB-YP769780HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human B-cell CLL/lymphoma 9-like protein(BCL9L) ,partial
  • 貨號：
    CSB-EP769780HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human B-cell CLL/lymphoma 9-like protein(BCL9L) ,partial
  • 貨號：
    CSB-EP769780HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human B-cell CLL/lymphoma 9-like protein(BCL9L) ,partial
  • 貨號：
    CSB-BP769780HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human B-cell CLL/lymphoma 9-like protein(BCL9L) ,partial
  • 貨號：
    CSB-MP769780HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    B-cell CLL; B-cell CLL/lymphoma 9-like protein; B-cell lymphoma 9-like protein; B9L; BCL9-2; BCL9-like protein; BCL9-related beta-catenin-binding protein; Bcl9l; BCL9L_HUMAN; DLNB11; Nuclear co factor of beta catenin signalling; Protein BCL9-2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1.
  • 基因功能參考文獻：
    1. we identify BCL9L as a novel regulator of TGF-beta-induced EMT in pancreatic cancer. PMID: 27713160
    2. BCL9L dysfunction contributes to aneuploidy tolerance in both TP53-WT and mutant cells by reducing basal caspase-2 levels and preventing cleavage of MDM2 and BID. PMID: 28073006
    3. The inhibition of the transcriptional activity of BCL9-2 by WWOX and HDAC3 constitutes a new molecular mechanism and provides new insight for a broad range of cancers. PMID: 25678599
    4. BCL9-2 induces ER positive breast cancers in vivo, regulates ER expression by a novel ss-catenin independent mechanism in breast cancer cells. PMID: 25149534
    5. Data show that beta-catenin/BCL9-Like (BCL9L)/T-cell factor 4 (TCF4) signalling directly targets the GCM1/syncytin pathway and thereby regulates the fusion of human choriocarcinoma cells. PMID: 22109522
    6. BCL9-2 promotes early phases of intestinal tumor progression in humans and in transgenic mice. BCL9-2 increases the expression of a subset of canonical Wnt target genes but also regulates genes that are required for early stages of tumor progression. PMID: 21703997
    7. Pygo2 PHD is the only known PHD finger that is capable of interacting simultaneously with two functional ligands, B9L and BCL9. PMID: 20637214
    8. crystallographic analysis of how beta-catenin, BCL9, BCL9-2 and Tcf4 interact PMID: 17052462

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    BCL9 family
  • 組織特異性：
    Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck
  • 數據庫鏈接：

    HGNC: 23688

    OMIM: 609004

    KEGG: hsa:283149

    STRING: 9606.ENSP00000335320

    UniGene: Hs.414740



主站蜘蛛池模板： 狠狠色狠狠色综合日日不卡| 久久好在线视频| 无码人妻丰满熟妇奶水区码| 国产精品天干天干有线观看| 狠狠久久噜噜熟女| 六十熟妇乱子伦视频| 亚洲精品一区久久久久| 色欲色香天天天综合网www| 国产产无码乱码精品久久鸭| 亚洲国产精品久久久久婷蜜芽| 成人精品视频一区二区三区尤物| 亚洲日韩性欧美中文字幕| 高中生粉嫩无套第一次| 99久久久无码国产精品9| 欧美叉叉叉bbb网站| 任我撸在线视频| 亚洲中文在线播放一区| 欧美孕妇xxxx做受欧美88| 久久久无码精品亚洲日韩按摩| 中国女人内谢69xxxxxa片| 亚洲理论在线a中文字幕| 人人莫人人擦人人看| 偷偷色噜狠狠狠狠的777米奇| 国产成人av免费观看| 国产成人剧情av麻豆果冻| 日韩一区二区三区无码人妻视频 | 国产午夜精品久久精品电影| 天堂а√在线地址8中文种子| 中国老熟女重囗味hdxx| 亚洲人亚洲精品成人网站| 国产av高清无亚洲| 午夜免费啪在线观看视频| 国产黑色丝袜在线视频 | 国产亚洲精品自在久久vr| 日韩毛片免费无码无毒视频观看| 国产人妻鲁鲁一区二区| 欧美成人aaaa免费全部观看 | 极品少妇扒开粉嫩小泬视频| 国内老熟妇乱子伦视频 | 亚洲最大成人网站| 乱亲女h秽乱长久久久|