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Recombinant Human Armadillo repeat protein deleted in velo-cardio-facial syndrome (ARVCF), partial

  • 中文名稱:
    Recombinant Human Armadillo repeat protein deleted in velo-cardio-facial syndrome(ARVCF) ,partial
  • 貨號:
    CSB-YP002162HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Armadillo repeat protein deleted in velo-cardio-facial syndrome(ARVCF) ,partial
  • 貨號:
    CSB-EP002162HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Armadillo repeat protein deleted in velo-cardio-facial syndrome(ARVCF) ,partial
  • 貨號:
    CSB-EP002162HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Armadillo repeat protein deleted in velo-cardio-facial syndrome(ARVCF) ,partial
  • 貨號:
    CSB-BP002162HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Armadillo repeat protein deleted in velo-cardio-facial syndrome(ARVCF) ,partial
  • 貨號:
    CSB-MP002162HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ARVCF
  • Uniprot No.:
  • 別名:
    Armadillo repeat gene deletes in velocardiofacial syndrome; Armadillo repeat protein; Armadillo repeat protein deleted in velo cardio facial syndrome; Armadillo repeat protein deleted in velo-cardio-facial syndrome; ARVC_HUMAN; Arvcf; FLJ35345; OTTHUMP00000028704; OTTHUMP00000198346; OTTHUMP00000198347; OTTHUMP00000198348
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in protein-protein interactions at adherens junctions.
  • 基因功能參考文獻:
    1. observed ARVCF-dependent changes in small GTPase (mainly RhoA) activity in lung cancer cells. We confirmed that ARVCF plays an important role in the malignant phenotype PMID: 25683624
    2. Carriage of the minor allele at rs2518824 in the armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF) gene was associated with white matter abnormality. PMID: 24819575
    3. Data indicate that armadillo repeat protein ARVCF interacts with the splicing factors the splicing factor SRSF1 (SF2/ASF), the RNA helicase p68 (DDX5), and the heterogeneous nuclear ribonucleoprotein hnRNP H2. PMID: 24644279
    4. Schizophrenic patients with more copies of the haplotype T-G-A-T-T-G-G-C-T-G-T (ARVCF-Hap1) have lower white matter integrity in caudate nucleus and greater perseverative errors. PMID: 22053977
    5. Five SNPs were validated as being significantly associated with prostate cancer mortality, one each in the LEPR, CRY1, RNASEL, IL4, and ARVCF genes. PMID: 21846818
    6. The functional variant rs165815, which affects a critical region of ARVCF, is a considerable source of the genetic variability associated with the risk of developing schizophrenia. PMID: 20333729
    7. Single nucleotide polymorphisms in the ARVGF gene are associated with the risk of schizophrenia. PMID: 19508883
    8. Evidence was found for association of illness to rs165849 in ARVCF, and a stronger signal from three-marker haplotypes spanning the 3' portions of COMT and ARVCF. Val(108/158)Met was in linkage disequilibrium with the markers in ARVCF. PMID: 15340358
    9. Interactions with zona occludens-1 and zona occludens-2, in particular, may mediate recruitment of ARVCF to the plasma membrane and the nucleus PMID: 15456900
    10. Results implicate a very close association of ARVCF with migrating neurons from the ganglionic eminence. PMID: 15509897
    11. Two haplotypes covering the catechol-O-methyltransferase-ARVCF region show significant transmission disequilibrium in anorexia nervosa-restricting Israeli-Jewish families PMID: 16118784
    12. Differential expression pattern of protein ARVCF in nephron segments of human kidney. PMID: 18600340
    13. Over-expression of TXNRD2, COMT and ARVCF affects incentive learning and working memory in transgenic mice. PMID: 19617637

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  • 蛋白家族:
    Beta-catenin family
  • 組織特異性:
    Found in all the examined tissues including heart, brain, liver and kidney. Found at low level in lung.
  • 數據庫鏈接:

    HGNC: 728

    OMIM: 602269

    KEGG: hsa:421

    STRING: 9606.ENSP00000263207

    UniGene: Hs.713616



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