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  4. Recombinant Human Apolipoprotein F (APOF)

Recombinant Human Apolipoprotein F (APOF)

  • 中文名稱：
    Recombinant Human Apolipoprotein F(APOF)
  • 貨號：
    CSB-YP001938HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Apolipoprotein F(APOF)
  • 貨號：
    CSB-EP001938HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Apolipoprotein F(APOF)
  • 貨號：
    CSB-EP001938HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Apolipoprotein F(APOF)
  • 貨號：
    CSB-BP001938HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Apolipoprotein F(APOF)
  • 貨號：
    CSB-MP001938HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    APOF
  • Uniprot No.：
  • 別名：
    Apo-F; Apof; APOF_HUMAN; Apolipoprotein F; DKFZp781G18150; Lipid transfer inhibitor protein; LTIP; MGC22520
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    165-326
  • 氨基酸序列
    SLPTED CENEKEQAVH NVVQLLPGVG TFYNLGTALY YATQNCLGKA RERGRDGAID LGYDLLMTMA GMSGGPMGLA ISAALKPALR SGVQQLIQYY QDQKDANISQ PETTKEGLRA ISDVSDLEET TTLASFISEV VSSAPYWGWA IIKSYDLDPG AGSLEI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
  • 基因功能參考文獻：
    1. Direct interactions between C/EBPalpha and ETS-1 were important for high liver-specific expression of ApoF. PMID: 25726912
    2. this study has identified apoF as likely another target gene of FXR. PMID: 24211198
    3. LTIP translocation is dependent on LDL lipid composition PMID: 21937674
    4. LTIP tailors CETP-mediated remodeling of HDL3 and HDL2 particles in subclass-specific ways, strongly implicating it as a regulator of HDL metabolism PMID: 12907677
    5. we have confirmed the negative association between plasma triglyceride levels and Apolipoprotein F previously suggested by a small data set, but now we demonstrate that this effect is seen only in males. PMID: 17901467
    6. lipoprotein composition may influence the status of lipid transfer inhibitor protein activity PMID: 18369235

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Apolipoprotein F family
  • 組織特異性：
    Expressed by the liver and secreted in plasma.
  • 數據庫鏈接：

    HGNC: 615

    OMIM: 107760

    KEGG: hsa:319

    STRING: 9606.ENSP00000381250

    UniGene: Hs.534302



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