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Recombinant Human Ankyrin repeat domain-containing protein 13D (ANKRD13D)

  • 中文名稱:
    Recombinant Human Ankyrin repeat domain-containing protein 13D(ANKRD13D)
  • 貨號:
    CSB-YP751183HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Ankyrin repeat domain-containing protein 13D(ANKRD13D)
  • 貨號:
    CSB-EP751183HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Ankyrin repeat domain-containing protein 13D(ANKRD13D)
  • 貨號:
    CSB-EP751183HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Ankyrin repeat domain-containing protein 13D(ANKRD13D)
  • 貨號:
    CSB-BP751183HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Ankyrin repeat domain-containing protein 13D(ANKRD13D)
  • 貨號:
    CSB-MP751183HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ANKRD13D
  • Uniprot No.:
  • 別名:
    ANKRD13DAnkyrin repeat domain-containing protein 13D
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-518
  • 氨基酸序列
    MVQLVLQYRD YQRATQRLAG IPELLNKLRQ APDFYVEMKW EFTSWVPLVS KMCPSDVYRV WKRGESLRVD TSLLGFEHMT WQRGRRSFIF KGQEAGALVM EVDHDRQVVH VETLGLTLQE PETLLAAMRP SEEHVASRLT SPIVSTHLDT RNVAFERNKC GIWGWRSEKM ETVSGYEAKV YSATNVELVT RTRTEHLSDQ DKSRSKAGKT PFQSFLGMAQ QHSSHTGAPV QQAASPTNPT AISPEEYFDP NFSLESRNIG RPIEMSSKVQ RFKATLWLSE EHPLSLGDQV TPIIDLMAIS NAHFAKLRDF ITLRLPPGFP VKIEIPLFHV LNARITFSNL CGCDEPLSSV WVPAPSSAVA ASGNPFPCEV DPTVFEVPNG YSVLGMERNE PLRDEDDDLL QFAIQQSLLE AGTEAEQVTV WEALTNTRPG ARPPPQATVY EEQLQLERAL QESLQLSTEP RGPGSPPRTP PAPGPPSFEE QLRLALELSS REQEERERRG QQEEEDLQRI LQLSLTEH
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
  • 基因功能參考文獻(xiàn):
    1. overexpression of wild-type as well as truncated-mutant Ankrd 13A, 13B and 13D proteins strongly inhibited rapid endocytosis of ubiquitinated EGFR from the surface in EGF-treated cells PMID: 22298428
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    3. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
  • 亞細(xì)胞定位:
    Cell membrane. Late endosome. Note=Interaction with EGFR may enhance association with the cell membrane.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 27880

    OMIM: 615126

    KEGG: hsa:338692

    STRING: 9606.ENSP00000427130

    UniGene: Hs.438673



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