在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1IP)

  • 中文名稱:
    Recombinant Human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(APBB1IP)
  • 貨號:
    CSB-YP773797HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(APBB1IP)
  • 貨號:
    CSB-EP773797HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(APBB1IP)
  • 貨號:
    CSB-EP773797HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(APBB1IP)
  • 貨號:
    CSB-BP773797HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(APBB1IP)
  • 貨號:
    CSB-MP773797HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    APBB1IP; PREL1; RARP1; RIAMAmyloid beta A4 precursor protein-binding family B member 1-interacting protein; APBB1-interacting protein 1; Proline-rich EVH1 ligand 1; PREL-1; Proline-rich protein 73; Rap1-GTP-interacting adapter molecule; RIAM; Retinoic acid-responsive proline-rich protein 1; RARP-1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-666
  • 氨基酸序列
    MGESSEDIDQ MFSTLLGEMD LLTQSLGVDT LPPPDPNPPR AEFNYSVGFK DLNESLNALE DQDLDALMAD LVADISEAEQ RTIQAQKESL QNQHHSASLQ ASIFSGAASL GYGTNVAATG ISQYEDDLPP PPADPVLDLP LPPPPPEPLS QEEEEAQAKA DKIKLALEKL KEAKVKKLVV KVHMNDNSTK SLMVDERQLA RDVLDNLFEK THCDCNVDWC LYEIYPELQI ERFFEDHENV VEVLSDWTRD TENKILFLEK EEKYAVFKNP QNFYLDNRGK KESKETNEKM NAKNKESLLE ESFCGTSIIV PELEGALYLK EDGKKSWKRR YFLLRASGIY YVPKGKTKTS RDLACFIQFE NVNIYYGTQH KMKYKAPTDY CFVLKHPQIQ KESQYIKYLC CDDTRTLNQW VMGIRIAKYG KTLYDNYQRA VAKAGLASRW TNLGTVNAAA PAQPSTGPKT GTTQPNGQIP QATHSVSAVL QEAQRHAETS KDKKPALGNH HDPAVPRAPH APKSSLPPPP PVRRSSDTSG SPATPLKAKG TGGGGLPAPP DDFLPPPPPP PPLDDPELPP PPPDFMEPPP DFVPPPPPSY AGIAGSELPP PPPPPPAPAP APVPDSARPP PAVAKRPPVP PKRQENPGHP GGAGGGEQDF MSDLMKALQK KRGNVS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
  • 基因功能參考文獻:
    1. Authors provide an overview of the structure and interactions of RIAM and discuss the implications of RIAM functions in innate and adaptive immunity and cancer. [Review] PMID: 28831022
    2. Disruption of the RIAM/lamellipodin-integrin-talin complex markedly impairs cell migration. PMID: 26419705
    3. RIAM is a critical component of the phagocytosis machinery downstream of Rap1 and mediates its function by recruiting talin to the phagocytic complement receptors. PMID: 23420480
    4. integrin-triggered, RIAM-dependent MEK activation represents a key feedback event required for efficient focal adhesion disassembly. PMID: 22946047
    5. RIAM was recruited to the lymphocyte plasma membrane through its Ras association and pleckstrin homology domains, both of which were required for lymphocyte adhesion. PMID: 23045549
    6. RIAM might contribute to the dissemination of melanoma cells. PMID: 21454517
    7. by regulating the localization of PLC-gamma1, RIAM plays a central role in TCR signaling and the transcription of target genes. PMID: 19952372
    8. all-trans-retinoic acid-inducible RARP1 selectively affects signal transduction and may contribute to myeloid and megakaryocytic differentiation.(RARP1) PMID: 14530287
    9. Data pinpoint PREL1 as the first direct link between Ras signalling and cytoskeletal remodelling via Ena/VASP proteins during cell migration and spreading. PMID: 15642358
    10. a minimized 50-residue Rap-RIAM module containing the talin binding site of RIAM joined to the membrane-targeting sequence of Rap1A. This minimized Rap-RIAM module was sufficient to target talin to the plasma membrane and to mediate integrin activation PMID: 19098287

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell junction, focal adhesion. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    MRL family
  • 組織特異性:
    Widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes.
  • 數據庫鏈接:

    HGNC: 17379

    OMIM: 609036

    KEGG: hsa:54518

    STRING: 9606.ENSP00000365411

    UniGene: Hs.310421



主站蜘蛛池模板: 久久久久女教师免费一区| 99久久久无码国产精品免费砚床 | 成人免费无码大片a毛片抽搐| 国产精品自产拍高潮在线观看| 好爽…又高潮了免费毛片| 欧美一区二区三区性视频| 久艾草在线精品视频在线观看| 欧美xxxxx精品| 亚洲国产日韩精品一区二区三区| 亚洲国产成人精品无码区在线秒播| 男女做爰猛烈啪啪吃奶伸舌头下载 | 99热成人精品热久久6网站| 亚洲精品人成网线在播放va | 中文有码亚洲制服av片| 天天爽夜夜爽夜夜爽精品视频| 人妻少妇乱子伦精品| 国产成人av在线免播放观看| 亲嘴扒胸摸屁股激烈网站 | 中文国产成人精品久久不卡| 亚洲www啪成人一区二区| 国产xxx视频在线观看软件| 国产女人水真多18毛片18精品| 野外做受又硬又粗又大视频| 香港经典a毛片免费观看hd| 男女久久久国产一区二区三区| 国产午夜福利精品久久2021| 肥臀浪妇太爽了快点再快点| 亚洲一码二码三码精华液| 男女啪啪高潮无遮挡免费| 无码精品人妻一区二区三区漫画| 国产成人免费97在线| 伊人久久大香线蕉综合狠狠| 亚洲人成色777777老人头| 日韩久久无码免费毛片软件 | 国产传媒精品1区2区3区| 亚洲一区二区三区影院| 天天做天天躁天天躁| 无码av片在线观看免费| 国产成人精品aa毛片| 99精品国产兔费观看久久99| 免费人成网站视频在线观看国内|