在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Alpha-2C adrenergic receptor (ADRA2C), partial

Recombinant Human Alpha-2C adrenergic receptor (ADRA2C), partial

  • 中文名稱：
    Recombinant Human Alpha-2C adrenergic receptor(ADRA2C),partial
  • 貨號：
    CSB-YP001390HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Alpha-2C adrenergic receptor(ADRA2C),partial
  • 貨號：
    CSB-EP001390HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Alpha-2C adrenergic receptor(ADRA2C),partial
  • 貨號：
    CSB-EP001390HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Alpha-2C adrenergic receptor(ADRA2C),partial
  • 貨號：
    CSB-BP001390HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Alpha-2C adrenergic receptor(ADRA2C),partial
  • 貨號：
    CSB-MP001390HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    ADRA2C; ADRA2L2; ADRA2RL2; Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2CAR
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
  • 基因功能參考文獻：
    1. The frequency of alpha2CDel322-325-AR in suicide and non-suicide victims was similar. Genotype frequencies for the alpha2CDel322-325-AR polymorphism in depressed and schizophrenic subjects were higher than in controls, but these differences did not reach statistical significance. The results indicate that alpha2CDel322-325-AR may play a role in the pathophysiology of opiate abuse and dependence. PMID: 27007576
    2. Immunoreactivity for ADRA2C was densely distributed in vascular smooth muscle of nasal turbinates. PMID: 26739946
    3. ADRA2c is associated with heart rate recovery after exercise. PMID: 26058836
    4. Common polymorphisms in the ADRA2C gene are not associated with orthostatic hypotension risk in Chinese. PMID: 26427149
    5. Adrenergic receptor genotype influences heart failure severity and beta-blocker response in children with dilated cardiomyopathy. PMID: 25406899
    6. alpha2C-adrenoreceptor interaction with filamin-2 PMID: 25110951
    7. Genetic variants of ADRA2C do not alter intracellular localization or plasma membrane trafficking. PMID: 24643471
    8. the ADRA2C 322-325I/D genotype is a novel genetic risk marker for SBI among individuals with hyperhomocysteinemia. PMID: 24676565
    9. the region comprising the N-terminal half of The receptors contributed to the alpha2C-selectivity of drug binding. PMID: 23868076
    10. Bucindolol prevents ventricular arrhythmias in subjects with heart failure and reduced left ventricular ejection fractions, and this effect is modulated by adrenergic alpha 2 receptor polymorphisms. PMID: 23275278
    11. the predicted signal peptide in the N-terminal tail of the alpha(2C)-adrenoceptor does not act as a cleavable signal peptide PMID: 22503931
    12. there is little evidence for an association between alpha(2C)Del322-325 polymorphism and an increased prevalence of left ventricular hypertrophy in patients with systemic hypertension. PMID: 22040172
    13. Genotype polymorphism frequencies for B1 receptor (amino acid positions 389 and 49) and alpha 2c receptor (deletion 322-325) are not significantly different in SC patients compared to female controls. PMID: 19167638
    14. The alpha(2C)-Del322-325 polymorphism does not exhibit reduced signalling to adenylyl cyclase and may not represent a clinically important phenotype. PMID: 20128806
    15. The common ADRA2C variant affected pain perception before and after dexmedetomidine but did not affect other cognitive responses PMID: 19423370
    16. the norepinephrine lowering and clinical therapeutic responses to bucindolol were strongly influenced by alpha(2C) receptor genotype PMID: 19880803
    17. Increased expression of alpha(2C)-adrenoceptors may contribute to enhanced cold-induced vasoconstriction and Raynaud's phenomenon. PMID: 15345481
    18. ADRA2C had one haplotype block of 10 kb PMID: 15592690
    19. alpha2CDel322-325 polymorphism is associated with increased sympathetic nervous and adrenomedullary hormonal activities, both during supine rest and during pharmacologically evoked catecholamine release PMID: 15861038
    20. A genetic variant of the alpha 2C-adrenoceptor subtype--resulting from the deletion of four consecutive amino acids at codons 322-325--confers a change in brain function playing a role in the pathogenesis of major depressive disorder. PMID: 16407897
    21. Genetic variations of the alpha and beta adrenergic receptors (alpha 2C Del322-325 allele) were found to be significant predictors of vasospastic angina PMID: 16569551
    22. alpha(2)-ARs might contribute neurotrophic actions in vivo synergistically or in permutation with other neurotrophic factors PMID: 17192578
    23. The ADRA2C deletion polymorphism had no effect on markers of resting sympathetic activity and cardiovascular measures, and did not account for ethnic differences in blood pressure. PMID: 17351367
    24. An estrogen-dependent increase in expression of cold-sensitive alpha(2C)-ARs may contribute to the increased activity of cold-induced vasoconstriction under estrogen-replete conditions PMID: 17644575
    25. Homozygosity for the alpha 2C Del322-325 polymorphism is not associated with heart failure in black South Africans PMID: 18320080
    26. Because the alpha(2C)-adrenoceptor distribution pattern is conserved between rodents and humans, studies on the role of the alpha(2C)-adrenoceptor in rodent models of neuropsychiatric disorders may be relevant also for human diseases. PMID: 18435421
    27. Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors. PMID: 18487435
    28. Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses PMID: 18698227
    29. Genotype and haplotype of ADRA2C did not significantly affect survival in metoprolol-treated or carvedilol-treated heart failure patients. PMID: 18702968
    30. Beta1- and alpha2c-adrenoreceptor variants as predictors of clinical aspects of dilated cardiomyopathy in people of African ancestry. PMID: 18776959
    31. Our findings provide important evidence that the ADRA2C polymorphism is involved in the etiology of ADHD in Korean subjects. PMID: 18835330
    32. Three polymorphisms in ADRA2C and five polymorphisms in ADRB1 were involved in eight cross-validated epistatic interactions identifying several two-locus genotype classes with significant relative risks of death/transplant in heart failure patients PMID: 18947427
    33. The ADRA2C del322-325 variant did not affect vascular sensitivity to local cold exposure. PMID: 19444546

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA2C sub-subfamily
  • 數據庫鏈接：

    HGNC: 283

    OMIM: 104250

    KEGG: hsa:152

    STRING: 9606.ENSP00000386069

    UniGene: Hs.123022



主站蜘蛛池模板： 国产做无码视频在线观看浪潮| 狠狠噜天天噜日日噜| 97久久综合区小说区图片区| 亚洲第一se情网站| 久久超碰色中文字幕超清| 男人边吻奶边挵进去视频| 免费看小12萝裸体视频国产| 国模杨依粉嫩蝴蝶150p| 天堂а√中文在线官网| 日本熟妇大乳| 欧美熟妇与小伙性欧美交| 久久国产超碰女女av| 国产精品av在线| www片香蕉内射在线88av8| 国产精品a国产精品a手机版| 中国熟女仑乱hd| 特黄aaaaaaaaa毛片免费视频| 乱中年女人伦av| 爆乳护士一区二区三区在线播放 | 午夜福利日本一区二区无码| 1000部拍拍拍18勿入免费视频下载 | 国产av午夜精品一区二区三 | 亚洲精品久久久久avwww潮水| 国产午夜精品一区二区| 天天躁日日躁狠狠躁2018 | 蜜臀av在线播放一区二区三区| 国产探花在线精品一区二区| 四十如虎的丰满熟妇啪啪| 婷婷五月综合色中文字幕| 性开放的女人aaa片| 亚洲日韩欧美一区二区三区在线| 亚洲欧美日韩中文二区| 国产真人做爰视频免费| 精品国产av色一区二区深夜久久| 亚洲最大av一区二区三区| 日本二区三区欧美亚洲国产| 亚洲爆乳大丰满无码专区| 国产成人无码精品久久久性色 | 亚洲色婷婷久久精品av蜜桃久久| 97无码免费人妻超级碰碰夜夜| 色噜噜亚洲男人的天堂www|