在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Alanine aminotransferase 2 (GPT2)

In Stock
  • 中文名稱:
    人GPT2重組蛋白
  • 貨號:
    CSB-EP823460HU
  • 規格:
    ¥1536
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    GPT2
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    65.3 kDa
  • 表達區域:
    1-523aa
  • 氨基酸序列
    MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.
  • 基因功能參考文獻:
    1. The GPT2 gene demonstrates increasing expression in brain in the early postnatal period, and GPT2 protein localizes to mitochondria. Akin to the human phenotype, Gpt2-null mice exhibit reduced brain growth. Through metabolomics and direct isotope tracing experiments, we find a number of metabolic abnormalities associated with loss of Gpt2 PMID: 27601654
    2. Recessively inherited loss of function GPT2 mutations are a novel cause of intellectual disability. PMID: 25758935
    3. ATF4 silencing prevented the activating effect of histidinol and tunicamycin on ATF4 and ALT2 expression. Our findings point to ALT2 as an enzyme involved in the metabolic adaptation of the cell to stress PMID: 24418603
    4. expression of GPT2 especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis. PMID: 11863375
    5. The biliary IL-6 and TNF-alpha levels were positively correlated with serum DBIL, TBA and gamma-GT levels in infantile hepatitis syndrome subjects. PMID: 17109502
    6. Elevation of liver enzymes and hepatic insulin resistance as reflected by fasting insulin occur in the early stages of insulin resistance and highlight the central role of the liver in insulin resistance in the general population. PMID: 17596883
    7. A clinical method for selective measurement of ALT1 and 2 in human plasma is described. PMID: 19360321

    顯示更多

    收起更多

  • 相關疾病:
    Mental retardation, autosomal recessive 49 (MRT49)
  • 蛋白家族:
    Class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily
  • 組織特異性:
    Expressed at high levels in muscle, adipose tissue, kidney and brain and at lower levels in the liver and breast.
  • 數據庫鏈接:

    HGNC: 18062

    OMIM: 138210

    KEGG: hsa:84706

    STRING: 9606.ENSP00000345282

    UniGene: Hs.460693



主站蜘蛛池模板: 国产成人精品三上悠亚| 在线精品自偷自拍无码中文| 国内精品视频一区二区三区| 丰腴饱满的极品熟妇| 青青国产揄拍视频| 韩国精品久久久久久无码| 内射人妻无码色ab麻豆| 精品国产乱码久久久久久郑州公司 | 男女性杂交内射女bbwxz| 精品亚洲国产成人av在线时间短的| 无码人妻少妇久久中文字幕蜜桃| 99re6这里有精品热视频| 色偷偷88888欧美精品久久久| 久久精品免费国产大片| 国产成人午夜福利电影在线播放| 亚洲熟妇无码爱v在线观看| 国产成人亚洲综合色婷婷| 国产精品高潮呻吟av久久小说| 国产韩国精品一区二区三区久久| 99在线精品一区二区三区 | 久久精品日日躁夜夜躁欧美| 日日鲁鲁鲁夜夜爽爽狠狠视频97 | 亚洲伊人久久成人综合网| 直接观看黄网站免费视频| 亚洲成av人片久久| 久久精品国产99精品国产2021| 熟妇人妻无码中文字幕老熟妇| 国产在线乱码一区二区三区| 玩两个丰满老熟女久久网| 射死你天天日| 亚洲综合最新无码专区| 久久久99精品成人片中文字幕| 国产乱人无码伦av在线a| 欲色影视天天一区二区三区色香欲| 久久综合久久爱久久综合伊人| 青青草原综合久久大伊人精品 | 日本一卡2卡3卡4卡无卡免费网站| 丰满饥渴老女人hd| 日韩内射美女片在线观看网站| 综合五月激情二区视频| 欧美牲交a欧美在线|