在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Adhesion G-protein coupled receptor G6 (ADGRG6), partial

  • 貨號(hào):
    CSB-EP768200HU
  • 規(guī)格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 來(lái)源:
    E.coli
  • 分子量:
    46.6 kDa
  • 表達(dá)區(qū)域:
    38-437aa
  • 氨基酸序列
    CANCRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYSNASFTQLLSFGKAKSGYFLSISDSKCLLNNALPVKEKEDIFAESFEQLCLVWNNSLGSIGVNFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEIVSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSCGSYLIPLPAAELASCADLGTLCQATVNSPSTTPPTVTTNMPVTNRIDKQRNDGIIYRISVVIQNILRHPEVKVQSKVAEWL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins. Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling. May act as a receptor for PRNP which may promote myelin homeostasis.
  • 基因功能參考文獻(xiàn):
    1. The association of a single nucleotide polymorphism in GPR126 with aggressive periodontitis in a Japanese population. The role of GPR126 in maintaining the homeostasis of periodontal ligament tissues. PMID: 27509131
    2. Together, these data uncover Gpr126 as a genetic cause for the pathogenesis of Adolescent idiopathic scoliosis (AIS) and pectus excavatum in a mouse model. PMID: 25954032
    3. Genetic variants of GPR126 gene are associated with adolescent idiopathic scoliosis susceptibility in Chinese populations. PMID: 25479386
    4. Mutations of GPR126 are responsible for severe arthrogryposis multiplex congenita. PMID: 26004201
    5. GPR126 modulates both physiological and pathological angiogenesis through VEGF signaling PMID: 25217645
    6. Gpr126 functions in Schwann cells for proper development and myelination through G-protein-signaling pathways. PMID: 24227709
    7. A single nucleotide polymorphism in the GPR126 gene is associated with increased susceptibility for adolescent idiopathic scoliosis. [Meta-analysis] PMID: 23666238
    8. Possible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms. PMID: 21929287
    9. The PS1TP2 gene was located at 6q24.1, and interacts with leukocyte proteins. PMID: 18304421
    10. VIGR represents a novel G protein coupled receptors of the adhesion family, which is unique in its long extra-cellular domain. PMID: 15225624
    11. APG1 formed an alpha-helical structure at the C-terminal site and a positive charge cluster at the N-terminal site. PMID: 17109822

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Lethal congenital contracture syndrome 9 (LCCS9)
  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 組織特異性:
    Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 13841

    OMIM: 606255

    KEGG: hsa:57211

    STRING: 9606.ENSP00000356581

    UniGene: Hs.743302



主站蜘蛛池模板: 亚洲中文字幕a∨在线| 一本色道无码道在线观看| 久久99久久99小草精品免视看| 久久久婷婷五月亚洲97色| 无码国产精品一区二区免费16| 性做久久久久久| 新版资源天堂中文| 国产美女视频免费观看网址| 欧美日韩在大午夜爽爽影院| 国产乱码精品一品二品| 亚洲成在人线av| 久久五十路丰满熟女中出 | 天堂网在线最新版www资源网| 久久综合伊人九色综合| 国产果冻豆传媒麻婆精东| 国产乱人伦中文无无码视频试看| 波多野结衣av无码| 久久精品99av高久久精品| 日本成a人片在线播放| 日本丰满熟妇hd| 国产女人18毛片水真多1| 尤物网址在线观看| 一本色道久久东京热| 精品综合久久久久久8888| 国产精品露脸国语对白| 亚洲 另类 日韩 制服 无码| 欧美丰满大爆乳波霸奶水多| 毛片免费全部播放无码| 久久精品中文字幕大胸| 亚洲精品无码不卡在线播放he| 国产又爽又大又黄a片| 久久99国产精品久久99果冻传媒| 午夜成人爽爽爽视频在线观看| 99久热国产精品视频尤物| 丰满人妻被黑人猛烈进入| 永久免费精品精品永久-夜色| 国产一区二区不卡在线看| 国产日韩欧美一区二区东京热| 国产做无码视频在线观看| 午夜三级a三级三点| 国产亚洲精品久久久久丝瓜|