在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Adenylate cyclase type 2 (ADCY2), partial

  • 中文名稱(chēng):
    Recombinant Human Adenylate cyclase type 2(ADCY2) ,partial
  • 貨號(hào):
    CSB-YP600106HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    Recombinant Human Adenylate cyclase type 2(ADCY2) ,partial
  • 貨號(hào):
    CSB-EP600106HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    Recombinant Human Adenylate cyclase type 2(ADCY2) ,partial
  • 貨號(hào):
    CSB-EP600106HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    Recombinant Human Adenylate cyclase type 2(ADCY2) ,partial
  • 貨號(hào):
    CSB-BP600106HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    Recombinant Human Adenylate cyclase type 2(ADCY2) ,partial
  • 貨號(hào):
    CSB-MP600106HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    ADCY2; KIAA1060Adenylate cyclase type 2; EC 4.6.1.1; ATP pyrophosphate-lyase 2; Adenylate cyclase type II; Adenylyl cyclase 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors.
  • 基因功能參考文獻(xiàn):
    1. In patients receiving capecitabine monotherapy, rs4702484, located in ADCY2 and close to MTRR, was associated with slightly reduced PFS for homozygous wild-type patients (CC 6.2 vs. CT 8.0 months; P=0.018). PMID: 25815774
    2. Our present study defines an AC2 cAMP signaling compartment that specifically regulates IL-6 expression in bronchial smooth muscle cells. PMID: 24363043
    3. AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex. PMID: 23889134
    4. A replication of association between two SNPs previously associated with COPD (CHRNA3/5 and IREB2), as well as an association with COPD of one locus initially associated with lung function (ADCY2). PMID: 22461431
    5. Data suggest that SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are potential prognostic markers in colorectal cancer. PMID: 21528083
    6. AC2 and AC4 isoforms, stimulated by GTP binding protein betagamma subunits, are expressed in bronchial nonlipid raft membrane fractions where they colocalize with and couple to prostanoid EP2 receptors. PMID: 21228062
    7. AC2 interacts with RXFP1 through AKAP79, whereas the association with PDE4D3 and PKA depends upon beta-arrestin 2 binding to Ser704. PMID: 20664520
    8. Clinical trial and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 18519826

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族:
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 組織特異性:
    Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Expressed in brain, especially in caudate nucleus, cerebellum and hippocampus.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 233

    OMIM: 103071

    KEGG: hsa:108

    STRING: 9606.ENSP00000342952

    UniGene: Hs.481545



主站蜘蛛池模板: 精品国产av 无码一区二区三区| 无码国产激情在线观看| 欧美牲交视频免费观看 | 久久视热这里只有精品| 无码人妻精品一二三区免费| 国产乡下妇女做爰| 国产午夜理论片不卡| 亚洲美女视频高清在线看| 小13箩利洗澡无码视频网站| 国产人妻精品久久久久野外| 人人妻一区二区三区| 国产卡二卡三卡四卡免费网址| 中国少妇大p毛茸茸| 精品人妻人人做人人爽夜夜爽 | 免费国产成人高清在线视频 | 暖暖视频日本在线观看| 国产综合色产在线精品| 婷婷色爱区综合五月激情| 国产av巨作丝袜秘书| 小宝极品内射国产在线| 东北妇女精品bbwbbw| 亚洲无线看天堂av| 国产清纯美女遭强到高潮| 少妇与子乱毛片| 日本肉体xxxx裸交| 99国产欧美另类久久久精品| 亚洲熟妇丰满xxxxx| 欧美又粗又大aaa片| 特级无码毛片免费视频| 国产99视频精品专区| 亚洲人成人无码网www电影首页| 香蕉久久国产av一区二区| 国产sm主人调教女m视频| 人妻av中文字幕一区二区三区| 亚洲中国最大av网站| 宅男噜噜噜66网站在线观看| 亚洲中文字幕无码爆乳app| 亚洲欧美精品综合在线观看| 久久综合久中文字幕青草| 久久精品国产99国产精品澳门| 亚洲精品国产精华液有哪些|