在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Achaete-scute homolog 2 (ASCL2)

Recombinant Human Achaete-scute homolog 2 (ASCL2)

  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-YP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-EP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-EP860358HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-BP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-MP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ASCL2
  • Uniprot No.：
  • 別名：
    ASCL2; BHLHA45; HASH2Achaete-scute homolog 2; ASH-2; hASH2; Class A basic helix-loop-helix protein 45; bHLHa45; Mash2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-193
  • 氨基酸序列
    MDGGTLPRSA PPAPPVPVGC AARRRPASPE LLRCSRRRRP ATAETGGGAA AVARRNERER NRVKLVNLGF QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL RPQAVRPSAP RGPPGTTPVA ASPSRASSSP GRGGSSEPGS PRSAYSSDDS GCEGALSPAE RELLDFSSWL GGY
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
  • 基因功能參考文獻(xiàn)：
    1. this study shows that Ascl2 level was higher in peripheral blood mononuclear cells from Sjogren's syndrome patients compared with those from healthy controls PMID: 28728856
    2. A novel HIF-1alpha/Ascl2/miR-200b regulatory feedback circuit in modulating EMT-MET plasticity of CRC cells, which could serve as a possible therapeutic target. PMID: 28899657
    3. WiNTRLINC1 interacts with TCF4/beta-catenin to mediate the juxtaposition of its promoter with the regulatory regions of ASCL2. PMID: 27292638
    4. Ascl2 over-expression is associated with colorectal neoplasms. PMID: 26307678
    5. expression of ASCL2 may identify an aggressive subgroup in lung squamous cell carcinoma PMID: 26483561
    6. SEMA3F functions as a suppressor of colorectal cancer metastasis by down-regulating the ASCL2-CXCR4 signaling axis. PMID: 25866254
    7. SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer. PMID: 25277775
    8. ASCL2 gene expression is regulated by miR-200a/b/c, miR-141 and miR429 levels in colon cancer. PMID: 25371200
    9. Ascl2 directly initiates follicular T-helper cell development PMID: 24463518
    10. These results suggest that ASCL2 might play an important role in gastric tumor growth and chemoresistance. PMID: 23181270
    11. Ascl2 knockdown results in tumor growth arrest by miRNA-302b-related inhibition of colon cancer progenitor cells PMID: 22384170
    12. a stem cell specific transcription signature promoted by ASCL2 has been identified to be upregulated in a subset of liver metastases, those characterised by an 11p15.5 gain PMID: 20479215
    13. These findings suggest that increased protein levels and DNA binding of USF1 and USF2 mediate the inhibitory effects of hypoxia and of Mash-2 on CYP19 gene expression in human placenta PMID: 12917334
    14. These results suggest that PACE4 expression is down-regulated by Hash-2/Mash-2 in both human and rat placenta and that many bioactive proteins might be regulated by PACE4 activity. PMID: 14561729
    15. ascl2 is a putative regulator of proliferation that is overexpressed in intestinal neoplasia PMID: 16568095
    16. Negative expression of HASH2 in complete hydatidiform moles (CM) but positive expression in malignant tumors suggests the presence of a specific mechanism for inactivation of the HASH2 gene in CM and reactivation in invasive moles or choriocarcinoma PMID: 17165436

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Expressed specifically in the extravillous trophoblasts of the developing placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 739

    OMIM: 601886

    KEGG: hsa:430

    STRING: 9606.ENSP00000332293

    UniGene: Hs.152475



主站蜘蛛池模板： 久久99精品国产免费观观 | 午夜国人精品av免费看| 中国国产1级毛卡片| 在教室伦流澡到高潮hgl视频| 国产乱人伦偷精品视频| 医院人妻闷声隔着帘子被中出| 18岁日韩内射颜射午夜久久成人| 久久香蕉国产线看观看猫咪av| 国产女主播喷水视频在线观看 | 国产精华av午夜在线| 巨胸不知火舞露双奶头无遮挡| 中文字幕人妻少妇引诱隔壁| 国产福利萌白酱精品一区 | 日本乱人伦aⅴ精品| 群交射精白浆视频| 日日噜噜夜夜狠狠视频| 国产精品久久久久7777按摩| 国产成年女人毛片80s网站| 亚洲精品高清无码视频| 国产女人高潮视频在线观看| 成人a片产无码免费视频在线观看| 亚洲国产a∨无码中文777| 女人喷液抽搐高潮视频| 国产成人一区二区精品视频| 亚洲国产成人综合在线不卡| 午夜天堂av天堂久久久| 东京道一本热中文字幕| 成 人 a v免费视频在线观看| 欧美毛多水多肥妇| 免费大黄网站在线观| 欧亚乱熟女一区二区三区在线| 老子影院无码午夜伦不卡| 欧洲亚洲精品久久久久| 色多多www视频在线观看免费| 亚洲精品专区成人网站| 极品粉嫩嫩模大尺度无码视频| 人妻熟人中文字幕一区二区| 国产成久久免费精品av片| 天天干天天日夜夜操| 久久久国产精品亚洲一区| 日韩人妻潮喷中文在线视频|