在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Achaete-scute homolog 2 (ASCL2)

Recombinant Human Achaete-scute homolog 2 (ASCL2)

  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-YP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-EP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-EP860358HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-BP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Achaete-scute homolog 2(ASCL2)
  • 貨號(hào)：
    CSB-MP860358HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ASCL2
  • Uniprot No.：
  • 別名：
    ASCL2; BHLHA45; HASH2Achaete-scute homolog 2; ASH-2; hASH2; Class A basic helix-loop-helix protein 45; bHLHa45; Mash2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-193
  • 氨基酸序列
    MDGGTLPRSA PPAPPVPVGC AARRRPASPE LLRCSRRRRP ATAETGGGAA AVARRNERER NRVKLVNLGF QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL RPQAVRPSAP RGPPGTTPVA ASPSRASSSP GRGGSSEPGS PRSAYSSDDS GCEGALSPAE RELLDFSSWL GGY
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
  • 基因功能參考文獻(xiàn)：
    1. this study shows that Ascl2 level was higher in peripheral blood mononuclear cells from Sjogren's syndrome patients compared with those from healthy controls PMID: 28728856
    2. A novel HIF-1alpha/Ascl2/miR-200b regulatory feedback circuit in modulating EMT-MET plasticity of CRC cells, which could serve as a possible therapeutic target. PMID: 28899657
    3. WiNTRLINC1 interacts with TCF4/beta-catenin to mediate the juxtaposition of its promoter with the regulatory regions of ASCL2. PMID: 27292638
    4. Ascl2 over-expression is associated with colorectal neoplasms. PMID: 26307678
    5. expression of ASCL2 may identify an aggressive subgroup in lung squamous cell carcinoma PMID: 26483561
    6. SEMA3F functions as a suppressor of colorectal cancer metastasis by down-regulating the ASCL2-CXCR4 signaling axis. PMID: 25866254
    7. SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer. PMID: 25277775
    8. ASCL2 gene expression is regulated by miR-200a/b/c, miR-141 and miR429 levels in colon cancer. PMID: 25371200
    9. Ascl2 directly initiates follicular T-helper cell development PMID: 24463518
    10. These results suggest that ASCL2 might play an important role in gastric tumor growth and chemoresistance. PMID: 23181270
    11. Ascl2 knockdown results in tumor growth arrest by miRNA-302b-related inhibition of colon cancer progenitor cells PMID: 22384170
    12. a stem cell specific transcription signature promoted by ASCL2 has been identified to be upregulated in a subset of liver metastases, those characterised by an 11p15.5 gain PMID: 20479215
    13. These findings suggest that increased protein levels and DNA binding of USF1 and USF2 mediate the inhibitory effects of hypoxia and of Mash-2 on CYP19 gene expression in human placenta PMID: 12917334
    14. These results suggest that PACE4 expression is down-regulated by Hash-2/Mash-2 in both human and rat placenta and that many bioactive proteins might be regulated by PACE4 activity. PMID: 14561729
    15. ascl2 is a putative regulator of proliferation that is overexpressed in intestinal neoplasia PMID: 16568095
    16. Negative expression of HASH2 in complete hydatidiform moles (CM) but positive expression in malignant tumors suggests the presence of a specific mechanism for inactivation of the HASH2 gene in CM and reactivation in invasive moles or choriocarcinoma PMID: 17165436

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Expressed specifically in the extravillous trophoblasts of the developing placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 739

    OMIM: 601886

    KEGG: hsa:430

    STRING: 9606.ENSP00000332293

    UniGene: Hs.152475



主站蜘蛛池模板： av第一福利网站| 男女啪啪高清无遮挡免费| 巨大巨粗巨长 黑人长吊| 内射少妇一区27p| 久久精品国产亚洲精品| 狠狠色噜噜狠狠狠777米奇小说| 亚洲人av在线无码影院观看| 欧美三级欧美成人高清| 强迫大乳人妻中文字幕| 中国少妇内射xxxhd| 亚洲欧美国产va在线播放| 久碰人妻人妻人妻人妻人掠| 无码人妻精品一区二区三区在线| 亚洲人成精品久久久久| 国产精品无码av片在线观看播| 欲香欲色天天综合久久| 产精品视频在线观看免费| 国产精品偷伦视频免费观看了| 狠狠色噜噜狠狠狠8888米奇| 亚洲欧美日韩国产综合v| 免费人成网站视频在线观看| 亚洲精品1卡2卡三卡23卡| 日本真人做爰免费视频120秒| 久久人妻无码一区二区| 狠狠cao2020高清视频| 国产午睡沙发被弄醒完整版| 樱花草在线社区www中国| 熟女人妻水多爽中文字幕| 久久久久无码中| 亚洲精品乱码一区二区三区| 97久久草草超级碰碰碰| 中文字幕一区二区三区精彩视频| 国产99在线 | 亚洲| 美女人妻激情乱人伦| 伊人精品成人久久综合97| 天天爱天天做狠狠久久做| 国产98在线 | 日韩| 一本到中文无码av在线精品| 无码日韩做暖暖大全免费不卡| 大肉大捧一进一出好爽视频| 变态 另类 欧美 大码 日韩|