在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ADP/ATP translocase 3 (SLC25A6), partial

  • 中文名稱:
    人SLC25A6重組蛋白
  • 貨號:
    CSB-YP021520HU1
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SLC25A6重組蛋白
  • 貨號:
    CSB-EP021520HU1-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SLC25A6重組蛋白
  • 貨號:
    CSB-BP021520HU1
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SLC25A6重組蛋白
  • 貨號:
    CSB-MP021520HU1
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    SLC25A6; AAC3; ANT3; CDABP0051; ADP/ATP translocase 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane. In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity. Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis. Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A6/ANT3 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity). Proton transporter activity requires free fatty acids as cofactor, but does not transport it. Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1.5 kDa, and which contributes to cell death. It is however unclear if SLC25A6/ANT3 constitutes a pore-forming component of mPTP or regulates it.
  • 基因功能參考文獻:
    1. Human ANT3 expression is directly downregulated by overexpression of hcmv-miR-UL36-5p. PMID: 26212361
    2. The dynamics of the molecular interactions between the C-terminal region of PB1-F2 protein and VDAC1 and ANT3 were expounded by employing an in silico approach. PMID: 19669810
    3. Of three ANT isoforms expressed in yeast, ANC3 is the most efficient to restore yeast growth on a nonfermentable carbon source of a yeast mutant strain lacking its three endogenous ANC. PMID: 12450408
    4. Results demonstrate that induction of adenine nucleotide translocase 3 by interleukin-4 and interferon-gamma proceeds via pathways involving STAT6 and STAT1, respectively. PMID: 14746803
    5. ANT3 overexpression induces apoptosis in cultured cells. PMID: 15063741
    6. ANT3 has a potential role in T-helper cell survival and immune cell homeostasis. PMID: 16930576
    7. involvement of ANT in cell death is cell type- and stimulus-dependent PMID: 17855512
    8. These data suggest that the down-regulation of ANT3 levels upon stimulation with CPT may be involved in the molecular mechanism underlying acquired resistance to camptothecin. PMID: 19111545

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family
  • 組織特異性:
    Expressed in erythrocytes (at protein level).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10992

    OMIM: 300151

    KEGG: hsa:293

    STRING: 9606.ENSP00000370808

    UniGene: Hs.350927



主站蜘蛛池模板: 欧美做爰性生交视频| 久久精品人人做人人综合试看| 成人美女黄网站色大色费全看| 亚洲精品久久国产高清小说| 亚洲全部无码中文字幕| 老色鬼永久精品网站| 成人无码av片在线观看| 97人妻人人做人碰人人爽| 精品国内自产拍在线播放观看| av无码天堂一区二区三区 | 男人的天堂2018无码| 被灌满精子的波多野结衣| 久久这里只精品国产免费10| 天堂网www中文在线| 99久久无色码中文字幕人妻| 欧美在线精彩视频免费播放 | 无码精品人妻一区二区三区98 | 日韩一区精品视频一区二区| 少妇性bbb搡bbb爽爽爽欧美| 一本一道av无码中文字幕| 亚洲性色成人av| 奇米777四色影视在线看| 亚洲欧美日韩综合一区二区| 国产精品激情欧美可乐视频| 999久久久无码国产精品| 波多野结衣办公室33分钟| 色播久久人人爽人人爽人人片av| 亚洲色在线v中文字幕| 午夜性爽视频男人的天堂| 午夜成人鲁丝片午夜精品| 狠狠色综合网站久久久久久久| 欧美极p品少妇的xxxxx| 肉体裸交137日本大胆摄影| 妓院一钑片免看黄大片| 亚洲人成无码www久久久| 97色伦综合在线欧美视频| 在线观看无码av免费不卡软件| 亚洲日本韩国| 国产薄丝脚交视频在线观看 | 99精品国产一区二区三区不卡| 国产av无码专区亚洲a∨毛片|